1.Study on the Nutrition Requirements of American Ginseng Ⅵ. Study on Nitrate Reductase Activity (NRA)of American Ginseng (Panax quinquefolius)
Xiaojun MA ; Zhen CHEN ; Yangjing ZHAO
Chinese Traditional and Herbal Drugs 1994;0(07):-
Two peaks were present in the NRA annual curve of Panax quinquefolius. A high peak appeared in late April and a smaller peak occured in early July. It is important to apply N2 fertilizers just before the appearance of the two peaks. Experiment on the effect of different light and pH showed that higher NRA were formed at 4000 Lx and pH 4.3~6.0.
3.Applications of syphon system in transurethal resection of prostate
Hongping TAO ; Weiping ZHAO ; Yangjing ZHU ; Shicheng YU ; Zhiqiang CHEN ; Dongyou ZHANG ; Yueping WANG
China Journal of Endoscopy 2017;23(3):1-8
Objective To explore the availability and safety of conducting low-pressure TURP assisted by a home-made cystometry and warning system.Methods 167 benign prostatic hyperplasia (BPH) patients admitted from Jan 2014 to Jan 2016 were randomly assigned into cystostomy group (group A) and non-cystostomy group (group B). In group A (n = 85), 42 patients (group A1) were performed percutaneous cystostomy + TURP, and 43 (group A2) were performed continuous flushing sheath TURP. In group B (n = 82), 42 patients (group B1) were received percutaneous cystostomy + TURP, and 40 (group B2) were received continuous lfushing sheath TURP. In group A, bladder pressure was monitored in real time with a cystometry and was monitored by bladder puncture using a home-made siphon, ensuring low bladder pressure throughout TURP. Serum Na+ levels were measured before and after operation in all four groups. The operation time, the intraoperative bleeding, the weight of resected prostates and the time before which urine turned clear were recorded. The IPSS, maximum lfow rate (Qmax), postvoid residual volume (PVR) and life quality score (QOL) were evaluated.Results While no significant differences were found between group A1 and A2, there were significant differences between group B1 and B2, indicating cystostomy group was safer than non-cystostomy group. When compared group A1 with B1, or group A2 with B2, it showed that the safe operation time to perform prostate tissue resection was longer in cystostomy group; the weight of the resected prostates was heavier; the time before which urine turned clear were shorter; and the IPSS improvement was better. These findings presented better therapeutic effects in cystostomy group than in non-cystostomy group.Conclusions This home-made cystometry and warning system could timely detect high bladder pressure state during TURP, making it possible to avoid of high pressure, ensuring low bladder pressure lfushing during the operation, lengthening the safe operation time, increasing tissue resection ratio, reducing transurethral resection syndrome, thus helping TURP to be safer.
4.Clinical analysis of 43 cases with carcinomas in maxillary sinus by sequent combination therapy.
Yanxia BAI ; Liying YAN ; Yangjing CHEN ; Liping SONG ; Ruimin ZHAO
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2008;22(23):1073-1076
OBJECTIVE:
To investigate the clinical effects and life quality of 43 cases with carcinomas in maxillary sinus by sequent combination therapy.
METHOD:
All the patients were subjected sequent and combination therapy, which included inductive chemotherapy through superficial temporal artery, operation and radical radiation therapy, and of these, 18 patients were added consolidation chemotherapy after combination therapy. Three year survival rate, 5- year survival rate and life quality were observed in a 5 years follow up.
RESULT:
All patients completed this therapy, the overall 5-year survival rates were 46.5% (20/43) and 3-year were 65.1% (28/43). None were undertaken orbital exenteration and 12 patients recovered their ability of work and manual labour.
CONCLUSION
The sequent combination therapy is an effective method to enhance the prospective efficacy of treating the carcinoma of maxillary sinus and can raise the local controlling rate. The induced chemotherapy through the temporal artery superficial has many advantages, such as high density of topical remedy, obvious tumor regression after only a cycle chemotherapy, not delaying the surgery opportunity and so on. The consolidation chemotherapy after this combined therapy can reduce the risks of distant metastasis further.
Adult
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Aged
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Carcinoma
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therapy
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Chemotherapy, Adjuvant
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Combined Modality Therapy
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Female
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Humans
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Male
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Maxillary Sinus Neoplasms
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therapy
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Middle Aged
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Quality of Life
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Survival Rate
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Temporal Arteries
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Treatment Outcome
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Young Adult
5.Effect of shenqi fuzheng injection on pre/post-operational change of argyrophilic-nucleolar organizer regions in peripheral T-lymphocyte in patients with gastric carcinoma.
Jin-quiang YANG ; Yong LI ; Qun ZHAO ; Gang KUANG ; Liqiao FAN ; Lili WANG ; Hui ZHANG ; Kun JIAO ; Hongwei ZHOU
Chinese Journal of Integrated Traditional and Western Medicine 2005;25(7):626-628
OBJECTIVETo investigate the pre-post operational change of argyrophilic-nucleolar organizer regions (Ag-NORs) in peripheral T-lymphocyte of patients with gastric carcinoma (GC), and to explore the effect of shenqi fuzheng injection(SFI) on it.
METHODSEighty five patients were divided into two groups according to the operation performed was radical or non-radical, and the two groups were subdivided into two by additional intravenous dripping of SFI was given to them or not. The content of Ag-NORs in peripheral T-lymphocyte in all patients before and after operation as well as in 12 healthy subjects was determined.
RESULTSContent of Ag-NORs in GC patients was significantly lower than that in the healthy subject (P < 0.01), which significantly increased after patients underwent radical operation (P < 0. 01 or P < 0.05), especially in those treated with SFI (P < 0.01). While in patients underwent non-radical operation but not treated with SFI, it showed insignificant change after operation, however it did significantly increase in those treated with SFI (P < 0.05).
CONCLUSIONThe immune function of T lymphocyte was low in patients with gastric carcinoma, post-operational adjuvant treatment of SFI can significantly improve the cellular immunity of patients.
Adjuvants, Immunologic ; therapeutic use ; Adult ; Aged ; Drugs, Chinese Herbal ; therapeutic use ; Female ; Humans ; Injections ; Male ; Middle Aged ; Nucleolus Organizer Region ; metabolism ; Phytotherapy ; Silver Staining ; Stomach Neoplasms ; drug therapy ; immunology ; surgery ; T-Lymphocytes ; immunology
6.Overexpression and clinical significance of PBX3 in acute myeloid leukemia
Hui Zhang ; Zixiang Chen ; Chunyi Zhao ; Qixiang Shao ; Yangjing Zhao
Acta Universitatis Medicinalis Anhui 2022;57(12):2012-2018,2024
Objective :
To investigate the expression levels and potential clinical significance of pre-B-cell leukemia homologous box 3 (PBX3) in bone marrow samples from acute myeloid leukemia (AML) .
Methods :
The mRNA expression levels of PBX3 were determined by bioinformatics which analyzed the RNAseq data of 33 malignancies from the cancer genome atlasdatabase. (TCGA) The correlations among the expression levels of PBX3,the clinical parameters and prognosis of AML patients were further analyzed.The differentially expressed genes in the whole transcriptome were analyzed to identify the molecular network in AML caused by PBX3 expression abnormalities.
Results :
The mRNA expression levels of PBX3 were up-regulated in 12 malignancies,and the altitudes increased most significantly in AML than any other cancer types.Patients with high PBX3 expression showed shorter overall survival and disease-free survival than patients with low PBX3 expression.High PBX3 expression was significantly associated with FLT3,NPM1,and DNMT3A mutation.PBX3 expression was positively correlated with multiple ho- meobox genes (including most HOXA and HOXB genes ,MEIS1 ) ,and the expression levels of these homeobox genes were all negatively correlated with AML patients overall survival.
Conclusion
PBX3 high expression in the bone marrow of AML patients is a potential biomarker for poor prognosis ,and it may have extensive interactions with other homeobox genes.