Sepsis,a common clinical syndrome,comparing to septicaemia or bacteremia,has a more comprehensive pathophysiological process.Its pathogenesis is complex,including pro-inflammatory/anti-inflammatory cytokine imbalance,intestinal bacterial translocation,immunosuppression,signal pathway activation,etc.Further study on the pathogenesis of sepsis is the theory foundation to explore the new method of sepsis.The diagnosis of sepsis pathogenesis,treatment principles and common virus infection induced sepsis are reviewed in this paper.

Drugs, Chinese Herbal ; therapeutic use ; Fatty Liver ; drug therapy ; Humans ; Phytotherapy ; methods ; trends

Objective To observe and explore the risk factors of nonalcoholic fatty liver diseas(NAFLD) complicated with hypertension in the enterprise retirees .Methods A total of 209 NAFLD patients diagnosed by ultrasound combined with questionnaire were collected in the enterprise retirees,and they were divided into the NAFLD with hypertension group(100 cases)and NAFLD without hypertension group (109 cases)after combined with physical examination results and past medical history.The relevant data of the two groups were retrospectively analyzed,and the risk factors of NAFLD complicated with hypertension disease were analyzed.Results The levels of age(t =1.69,P <0.05),body mass index(BMI)(t =0.36,P <0.05),waist circumference(t =0.64,P <0.05), total cholesterol(TC)(t =2.31,P <0.05),total bilirubin(TBS)(t =6.83,P <0.05),serum creatinine(Scr)(t =2. 20,P <0.05)in NAFLD complicated with hypertension group were higher than those in NAFLD group,and the differ-ences were statistically significant(P <0.01 or P <0.05).The logistic regression analysis showed that TC(OR =4.2)was the independent influencing factor of NAFLD with hypertension.Conclusion NAFLD is closely associated with hypertension,NAFLD can be incorporated into chronic disease management system with high blood pressure in order to improve the value of the disease in the elderly,and it is conducive to the further study of NAFLD and the management of other chronic disease.

Objective To explore the effect of community family nursing intervention on glycemic control of type 2 diabetic patients. Methods Ninety-two patients with type 2 diabetes after discharge in 6 communities of Tianhe District in Guangzhou were divided into a study group and a control group , 46 cases in each . The control group received routine care , while patients in the study group received additional community family nursing intervention, including personalized health education, diabetes family day and sharing, telephone follow-up and family home visits. The fasting plasma glucose, 2h-postprandial glucose and glycosylated hemoglobin A1c were compared. Results There were no significant differences in fasting plasma glucose, 2h-postprandial glucose and glycosylated hemoglobin A1c (all P>0.05). After intervention, there were significant differences in the three eridoxes between the two groups(all P<0.05). Conclusion The community family nursing intervention is of great importance to control the blood glucose, improve the therapeutic compliance and self-management ability in patients with type 2 diabetes.

During 1920-30s,under the push of Kuomintang,Communist Party and social personage,the Chinese village launched a cooperation movement. Although they failed to renew rural areas in China,the farmer autonomy spirit, policy practicality,the educational principles,and the spirit of evidence-based demonstration research embodied in the movement still have an enlightening significance to the construction of the new rural cooperative healthcare system and construction of new-type villages.

OBJECTIVE:To offer suggestions for domestic hospitals in the introduction of automated unit-dose dispensing equipment.METHODS:The application value and problems arose from the introduction of automated unit-dose dispensing machine were analyzed by summarizing our experience and reviewing literature.RESULTS:The use of automatic machines could avoid drug pollution and cross infection and reduce the incidence of medication errors during drug dispensing and administration.However,its application has also resulted in problems such as additional machine errors more costs and management difficulties.The introduction of the machine should be based on rational demands and proof analysis.Moreover,it is more suitable for the unit-dose dispensing in inpatient dispensary.CONCLUSIONS:Automatic drug dispensing is the trend of development.The application of new equipment can bring new problems as well as challenges,thus it is urgent to explore new management model.

OBJECTIVE:This article discusses the development of a new commodity flow pattern,acting delivery,in Chi?nese pharmaceutical circulation.METHODS:Using comparative method to analyze the reasons,the operating framework and the present strategies on developing acting delivery.RESULTS&CONCLUSION:The new pattern of acting delivery is con?ducive to reduce pharmaceutical circulation cost,to strengthen enterprises'competitiveness and to use social resources more rationally.That is an inevitable development tendency for Chinese pharmaceutical circulation market and for following inter?national practice.

OBJECTIVE:To provide reference material for standardization of lice ns ed pharmacist's consultation service METHODS:From the angle of The Law of Pro tecting Consumer's Rights and Interests,the legal relation between pharmacist and customer,rights and duties of the two parties and fair-honest dealings wer e analysed RESULTS & CONCLUSION:In the new pharmaceutical service,the licens ed pharmacists should take public health as the focus of work,carry out consult ation service according to law,so as to promote the development of social healt h undertaking

OBJECTIVE:To introduce methods of cost categorizing in pharmacoeconomics evaluation and existing controversy METHODS:To compare different cost measurement methods and definition in different pharmacoeconomic guideline RESULTS & CONCLUSION:Choosing appropriate cost spectrum corresponding to different studing aspects

OBJECTIVE:To discuss the risk in clinical pharmacy service in order to provide reference for Chinese hospitals in both guarding against and reducing risk.METHODS:This study adopted a classified method to set forth the tactics on re?ducing risk of both organization and individual person in clinical pharmacy practice after analyzing the risk factors.RESULTS&CONCLUSION:It is important for the working personnel who engage in clinical pharmacy work to heighten their con?sciousness of risk and to strengthen managing it.