1.Clinical study of the treatment principle of Yangyin-Huayu for the patients with recurrent ;hemoptysis of bronchiectasis
International Journal of Traditional Chinese Medicine 2016;38(10):898-901
Objective To observe the clinical curative effect and the serum CPR changes by the treatment principle of Yangyin-Huayu for the patients with recurrent hemoptysis of Bronchiectasis. Methods A total of 64 patients were enrolled and divided into 2 groups according to the random number table method, 32 patients in each group. The control group was treated with the injection of blood clotting enzyme, pituitrin, levofloxacin lactate. And the treatment group was treated with the Yangyin-Huayu on the basis of the control group. Two groups were treated for 10 days. The CPR was detected by the double optical path immune turbidity analyzer. And the clinical effects, symptoms and signs scores were compared between before and after treatment and between two groups. Results Compared with the total effective rate of control group 84.38%(27/32), the treatment group was 96.88% (31/32) and significantly high (χ2=6.372, P<0.01). After treatment, the levels of serum CPR (2.45 ± 1.42 mg/L vs. 6.19 ± 2.34 mg/L, t=4.671) in the treatment groupwas significantly lower than that in the control group (P<0.01). The scores of cough (0.62 ± 0.91 vs. 1.34 ± 0.58, t=5.364), sputum (0.14 ± 0.28 vs. 0.68 ± 0.72, t=4.035), haemoptysis (0.10 ± 0.65 vs. 0.62 ± 0.26, t=5.012), fever (0.04 ± 0.31 vs. 0.76 ± 0.07, t=3.026), breathing difficulties (0.12 ± 0.41 vs. 0.69 ± 0.05, t=4.010) in the treatment group were lower than those in the control group (P<0.01). Conclusions The treatment principle of Yangyin-Huayu combined with conventional western medicine therapy can improve the patients with recurrent hemoptysisin the fields of symptoms, signs, the serum level of CPR, and total effect rates.
2.On the Strategies of Pharmaceutical Development in the West of China
China Pharmacy 1991;0(04):-
OBJECTIVE: To propose feasible strategies for the pharmaceutical development in the West of China METHODS:To analyse the pharmaceutical industry,pharmaceutical business,traditional Chinese medicine and current national pharmaceutical situation,and the existing problems in the West RESULTS & CONCLUSION:A series of strategies concerning the pharmaceutical development in the West are brought forth in order to promote the healthy development of the pharmaceutical industry there ,including ideology strategy,sustainability strategy,innovation strategy,talent strategy,policy strategy,methodology strategy,management strategy,patent strategy,and brand strategy
3.Study on Mechanism of Action of Compound Huanggan Granules on the Kidney
China Pharmacy 2001;0(08):-
OBJECTIVE:To research the mechanism of action of compound Huanggan gr anules(FHG) METHODS:To observe the effect of FHG on the renal blood flow and glomerular filtration rate,and its mechanism of diuresis by means of isotopic tracer,electromagnetic flowmeter and ureter catheterization RESULTS:FHG could significantly increase the renal blood flow and glomerular filtration rate,and enhance the diuresis CONCLUSION:Its diuresis is based on the increase of rena l blood flow and glomerular filtration rate,which results in the decrease of ne phrotoxic substances such as blood urea nitrogen and serum creatinine
4.Tissue engineering technology for repair of meniscus injury:from basic to clinic
Chinese Journal of Tissue Engineering Research 2016;20(11):1651-1657
BACKGROUND: The use of tissue engineering technology to build a functional meniscus is a new idea for repair of meniscus injury. OBJECTIVE: To analyze the research progress of seed cells and scaffold materials in tissue-engineered meniscus repair. METHODS: A computer-based search of CNKI and PubMed was performed for articles related to tissue-engineered meniscus repair published from 1996 to 2015. The keywords were meniscal repair, meniscal injury, tissue engineering, tissue-engineered meniscus, biomaterials, stem cells in Chinese and English, respectively. RESULTS AND CONCLUSION: Tissue-engineered meniscus reconstruction is a more viable method for repair of meniscus injury. Mesenchymal stem cells are pluripotent cells that are ideal seed cells for tissue-engineered meniscus reconstruction. Scaffolds are one of important factors for meniscus repair, and natural meniscal scaffolds play an important role. Selection and development of scaffold materials for meniscus tissue engineering have experienced a rapid development period from a single material to composite materials. Composite materials make up a lot of shortcomings and deficiencies that a single material has, and open up new ideas for developing new materials. Meniscal tissues with geometric shapes can be constructed using tissue engineering technology. However, the long-term observation of the biological properties of meniscal tissues is necessary, and from basic to clinic, there is still a lack of reliable data to prove the effect of tissue engineering technology in the meniscus repair.
5.Artificial ligament biomaterials repair cruciate ligament injury of the knee joint:problems and prospects
Chinese Journal of Tissue Engineering Research 2016;20(8):1196-1202
BACKGROUND: Related studies have confirmed that the experimental results and short-term clinical outcomes of artificial ligaments are satisfactory that the artificial ligaments can restore the stability of knee joint as soon as possible and ensure motor function. OBJECTIVE: To summarize the basic and clinical research progress of artificial ligaments. METHODS: The articles regarding artificial ligaments in repair of knee joint cruciate ligament injury were retrieved from Wanfang database, CNKI and PubMed database during 1985 to 2015 by computer. The keywords were “cruciate ligament injuries, artificial ligament, biological materials” in Chinese and English, respectively. RESULTS AND CONCLUSION: Compared with autologous and al ogenic ligaments, artificial ligament has good mechanical properties, and can get sufficient tensile strength and joint stability immediately after implantation, so as to ensure the cruciate ligament reconstruction of the knee joint. Artificial ligament technology has experienced carbon fiber ligament, polyester material and stent artificial ligaments. As a new type of polyester artificial ligament, LARS artificial ligament shows a good biocompatibility, on which, cel s can adhere, proliferate and differentiate wel . However, the controversies over the use of artificial ligament stil exist, and its long-term clinical effects stil need further observation. Further researches regarding the material selection, shape bionic design, weaving and surgical techniques of artificial ligaments are stil further needed.
6.The application of PBL and CBS in genetics teaching
Chinese Journal of Medical Education Research 2006;0(11):-
Objective Using PBL and CBS pedagogy,to explore the feasibility of the application and effectiveness of teaching in medical genetics teaching. Methods In medical genetics teaching,set the clinical Class 1 grade 2007 to the control group,using traditional pedagogy,set the clinical Class 2 grade 2007 to the experimental group,using PBL and CBS pedagogy. Results Final exam results showed that the experimental group's average scores were significantly higher than control group(P
7.Analysis of prognostic risk factors in elderly patients with acute coronary syndrome
Chinese Journal of Geriatrics 2011;30(6):460-463
Objective To explore short-term prognosis of patients with acute coronary syndrome (ACS) and prognostic risk factors, and to provide information for prognostic risk assessment. Methods A total of 156 patients with acute coronary syndrome were enrolled. The correlations of baseline characteristics with 30-day improvement, death, angina pectoris and heart failure were analyzed using unordered multivariate logistic regression. Results Logistic regression analysis showed that the independent risk factors for 30-day death included age (OR=1.20, 95%CI: 1.07-1.34), diabetes (OR=19.41, 95%CI: 3.02-124.70), leukocytosis (OR=11.36, 95%CI: 1.87-69.11) and increased platelet (OR=7.72, 95%CI: 1.29-46.15). The independent risk factors for 30-day angina pectoris included leukocytosis (OR=2.35, 95%CI: 0.89-6.17) and dyslipidemia (OR=6.25, 95%CI: 2.11-18.48). The independent risk factors for the occurrence of heart failure during 30-day post-ACS included age (OR=1.10, 95%CI: 1.03-1.17), male (OR=4.18, 95%CI: 0.81-21.51), leukocytosis (OR=2.97, 95%CI: 1.09-8.14) and dyslipidemia (OR=7.69, 95%CI: 2.39-24.76). Conclusions Age, diabetes, leukocytosis and increased platelet are independent risk factors associated with 30-day death; Leukocytosis and dyslipidemia are independent risk factors associated with 30-day angina pectoris; Age, male, leukocytosis and dyslipidemia are the independent risk factors associated with 30-day heart failure.
8.Design and Implementation of Medical Expenses Statistics and Verification System in Outpatient Department of Military Hospital
Chinese Medical Equipment Journal 1993;0(05):-
Objective To realize scientific and high efficient and digital management of medical expenses statistics and verification work in outpatient department of military hospital. Methods Based on the Oracle database of HIS system, Delphi programming language was used to construct the system. Results The system has been successfully applied in hospital actual work with satisfactory results. Conclusion The use of the system can provide transparent and efficient management platform for hospital economic accounting work, and give scientific and numerical gist for hospital operating decision-making.
9.Research on the advances in the studies of VEGF and its receptors in gastric cancer
Li YANG ; Jianzhang HOU ; Zhenjiang HOU
China Medical Equipment 2014;(4):68-70
Neovascularization is the basis of tumor growth and metastasis. Angiogenesis depends mainly on the regulation of vascular endothelial growth factor and angiogenesis inhibiting factor. The vascular endothelial growth factor and its receptor are the most important and are studied most. The expression of them increased significantly in gastric cancer tissue and serum.. They promote angiogenesis of tumor. They are closely related to the prognosis of patient. The vascular endothelial growth factor and its receptor in the gastric cancer are reviewed in this article.
10.Effects of dopamine alone or dopamine plus norepinephrine on hemodynamics, tissue oxygenation and renal function during orthotopic liver transplantation
Liping ZHANG ; Lu YANG ; Juan HOU
Chinese Journal of Anesthesiology 1994;0(03):-
Objective To evaluate the effects of dopamine (DA) alone or DA plus norepinephrine (NE) on hemodynamics, tissue oxygenation, acid-base balance and renal function during orthotopic liver transplantation (OLT).Methods Thirty ASA IE or IV patients undergoing OLT were randomly divided into 2 groups of 15 patients each. In group A DA was continuously infused during operation. The initial infusion rate was 1-3 ?g?kg-1 ?min-1 . The rate was then adjusted to MAP between 60-80 mmHg. While in group B DA and NE were continuously infused. The initial infusion rate of DA was 1-3 (?g?kg-1?min-1 and that of NE 0.03 ?g?kg-1?min-1 . Both rates were adjusted to MAP between 60-80 mm Hg but the maximal DA infusion rate was 5 ?g?kg-1?min-1 . Anesthesia was induced with midazolam, propofol, fentanyl and vecuronium and maintained with isoflurane inhalation, continuous propofol infusion and intermittent i.v. boluses of fentanyl, midazolam and pipecuronium. Radial artery was cannulated and S-G catheter was placed via right internal jugular vein. Hemodynamic variables such as MAP, CVP, PAP, PCWP, SVRI, PVRI, blood gases, mixed venous blood O2 saturation (SvO2), blood lactate, Cr and BUN were measured and O2 delivery (DO2 ) and O2 consumption (VO2 ) were calculated and recorded after induction and before surgery (T1 baseline), 60 min after operation was started (T2), at 60 min anhepatic phase (T3) and 60 min neohepatic phase (T4 ) and at the end of operation ( T5). Results There were no significant differences between the two groups with respect to age, sex, body weight, duration of operation and types of surgery. MAP and HR were quite stable in both groups. CVP, MPAP, PCWP, cardiac output (CO) and CI were significantly decreased while SVR and SVRI were increased during anhepatic phase (T3 ) in both groups ( P

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