1.Clinical Efficacy and Safety Evaluation of Loratadine Combined with Compositus Mentholi Cream in the Treatment of Infantile with External Ear Eczema
China Pharmacist 2016;19(7):1314-1316
Objective:To investigate the clinical efficacy of loratadine combined with compositus mentholi cream in the treatment of infantile with external ear eczema and evaluate the safety .Methods:Totally 96 cases of infantile with external ear eczema were ran-domly divided into the observation group (n=48) and the control group (n=48) according to a random number table .Both groups were given the conventional treatment .The control group was treated with topical compositus mentholi cream , while the observation group was treated with loratadine additionally .Both groups were treated for 10 d.The clinical efficacy , the level changes of interleukin-4 (IL-4), interferon-γ(IFN-γ) and immunoglobulin-E (IgE) before and after the treatment, the incidence of adverse reactions during the treatment and the relapse after 6-month follow-up were compared between the groups .Results:The total effective rate of the obser-vation group (95.83%) was significantly higher than that of the control group (79.17%, P<0.05); the levels of IL-4, IFN-γand IgE in both groups were significantly decreased after the treatment (P<0.05), and those in the observation group were significantly lower than those in the control group (P<0.05);there was no significant difference in the incidence of adverse reactions between the groups (P<0.05); the recurrence rate in the observation group (8.33%) was significantly lower than that in the control group (22.92%, P<0.05).Conclusion:The clinical efficacy of loratadine combined with compositus mentholi cream in the treatment of infantile with external ear eczema is reliable with promising safety .
2.WeChat service in hospitals directly under the Yunnan Health and Family Planning Commission
Chinese Journal of Medical Library and Information Science 2016;25(3):73-75
The WeChat service provided at present in 14 hospitals directly under the Yunnan Health and Family Planning Commission was surveyed with suggestions proposed for providing active Wechat service in hospitals in order to alleviate the difficulty to see a doctor and the tense relationship between doctors and patients.
3.Expression and location of IL-2/IFN-? fusion protein in colorectal tumor cell lines
Chinese Journal of Practical Internal Medicine 2006;0(18):-
Objective If IL-2 and IFN-? are united,perhaps we may see a more significant antitumor effect.A fusion gene of IL-2 and IFN-? was designed and constructed by DNA engineering.Methods CEA promotor、IL-2cDNA and IFN-?cDNA were obtained by PCR and RT-PCR.SDS-PAGE was used to examine the results;pcDNA-IL-2、pcDNA-IFN-?、pCEA-IL-2/ IFN-?、pEGFP-IL-2/ IFN-? were transfected to CEA high expression cell line(Lovo)by use of liposome.The fusion protein expression was examined by fluorescence microscope and Western blotting.Results IL-2/ IFN-? fusion gene can be expressed in tumor cells.Its expression is more obvious in CEA high expressed cells(Lovo),and can be located in cell plasma.Conclusion The fusion gene can be expressed in plasma of CEA high expressed cell lines.It may have a new anti-tumor effects.
4.Reading therapy in different kinds of library:A comparative analysis
Chinese Journal of Medical Library and Information Science 2014;(1):45-47
Reading therapy in hospital libraries, academic libraries and public libraries was described in terms of its theoretical study and practical study,and its significance in hospital library was elaborated by comparative analysis.
5.Advances in mechano-biological behavior of peridontal ligament during orthodontic tooth movement
International Journal of Biomedical Engineering 2013;36(6):367-370,380
Orthodontic tooth movement (OTM) is a very complicate mechano-biological procedure which is accomplished by the remodeling of periodontal tissues via orthodontic force.As the connective tissue between alveolar bone and cementum,periodontal ligament plays a vital role in the response and conduction of orthodontic force.The susceptible response of periodontal ligament to orthodontic force during OTM is a critical factor on inducing and modulating periodontal tissue restitution.This article reviews the concrete role of periodontal ligament and its mechano-biological behavior during OTM,discusses its mechanical response and biological mechanism respectively on histological,cellular and moleucular levels.
6.Analysis of cervical cancer screening results in 13 297 rural women in Gaoping City
Chinese Journal of Primary Medicine and Pharmacy 2016;23(7):1052-1055
Objective To analyze the results of cervical cancer screening in 13 297 rural women in Gaoping during 2012-2015,and to explore more suitable way for rural women in the examination of cervical cancer.Methods According to theShanxi province rural women cervical cancer check project implementation plan,combined with the actual situation of Gaoping city,the gynecological examination of 13 297 married women in Gaoping city,vaginal and cervical secretions smear, cytology of cervical cytology ( TCT ) , to check the abnormal of the Department of Gynaecology and the abnormal cervical cytology, pathological examination of the cervix of the uterus with abnormal vaginal examination.Results A total of 6 965 cases of infection of the reproductive tract were examined, the prevalence rate was 52.38%.Among them,4 968 cases of cervicitis (37.36%),849 cases of trichomonas vaginitis (6.38%),Candida albicans vaginitis in 988 cases (7.43%),bacterial vaginal disease in 1 364 cases (10.26%), pelvic inflammatory disease in 1 348 cases (10.14%).Cervical cytology examination of ASC -US and the above cases in 418 cases (3.14%),ASC-US examination rate was 1.78%,the rate of ASC-H was 0.28%,the rate of LSIL was 0.60%,and the rate of HSIL was 0.47%.Detection of cervical precancerous lesions and cervical cancer cases,among them CIN I 81 cases,the incidence rate was 609.16/10 million,CIN II 29 cases,incidence rate was 218.09/10 million,16 cases of CIN,incidence rate was 120.33/10 million.The detection rate of precancerous lesions was 338.42/10 million.Cervical carcinoma in situ:1 case,9 cases of invasive cervical cancer,the detection rate of cervical cancer was 75.20/10 million.Conclusion Cervical cancer screening is helpful to improve the early detection rate of cervical cancer in rural women,safeguarding women's reproductive health.At the same time to carry out the census,vigorously promote health knowledge is also very important.
7.Study of Anti-CD9, CD10 immunotoxins to kill leukemiccell and the effect, on hemopoiesis
Chinese Journal of Immunology 1985;0(05):-
Immunotoxin consists of the antibody, which can specifically recognize relative antigen on the surface of leukemic cell, and intact ricin, which kill cell. It is very profitable to eliminate leukemic cell from bone marrow for prophylaxis of leukemia relapse after bone marrow transplantation. In the study, we reported that clongoenic leukemic cell (Nalm-6) were eliminated by two different immunotoxins (with CD9 and CD10). The inhibiting effect of immunotoxins in useful dose on the proliferation of hemopoietic progenitor cells (CFU-mix, BFU-E and CFU-GM) was not obviously.It is probably that immunotoxins will be used in autologous bone marrow transplation.
8.The bioethics and the international law:look back and unification
Chinese Medical Ethics 1995;0(02):-
Looking back to the history of the 20th century contributes to the rise of bioethics and the unification of international law on the present age.In the times of rapid scientific and economic development,it is either a core issue of bioethics or a starting point of international law that how humans should survive and establish a relationship with the nature.And a series of common behavior criteria for human being are being or will being established to seek a co-existent path between peoples as well as between human being and nature.
9.Preparation of 4-Paramisan Sodium Colon-specific Delivery Coated Tablets and the Determination of Its Drug-releasing Rate
China Pharmacy 2005;0(16):-
0.05).CONCLUSION:4-paramisan sodium oral colon-specific delivery coated tablets coated in turn with permeable and enteric soluble acrylic resin has ideal specific delivery and slow-release properties,the coating technology was stable and the reproducibility is good.