Humans ; Practice Guidelines as Topic ; Research Design

Meta-Analysis as Topic

Animals ; Evidence-Based Medicine ; Health Knowledge, Attitudes, Practice ; Humans ; Infant ; Meta-Analysis as Topic ; Milk Hypersensitivity ; diagnosis ; prevention & control ; Milk Proteins ; adverse effects ; Practice Guidelines as Topic ; standards ; Professional Staff Committees ; organization & administration

Due to the serious shortage of donor cornea materials and the donor limit, clinical popularization of penetrating keratoplasty is severely restricted. lt is a hot spot of current research that applying tissue engineering in vitro to culture corneal endothelial cells ( CEC ) with high density, regular hexagonal shape and healthy endothelial function. ln this article, we reviewed the latest progress in the study of source of CEC seeder cells, selection of cultivating carries, type of CEC transplantation and immune mechanism that summarized the current research problems and made a prospect to the future.

Child ; Humans ; Incisor ; abnormalities ; Maxilla ; Occlusal Adjustment ; Orthodontic Extrusion ; Tooth Abnormalities ; diagnosis ; etiology ; therapy ; Tooth, Impacted ; diagnosis ; etiology ; therapy

Objective To investigate the diagnostic method and surgical therapeutic outcome of small peripheral pulmonary nodules (diameter ���2cm). Methods The data of 122 patients with small peripheral pulmonary nodules who were admitted from Jan. 2001 to Oct. 2010 and diagnosed by pathology postoperatively were retrospectively analyzed. The nodule diameter of nodules in 101 cases were 1-2 cm, and they were less than 1 cm in 21 cases. All the patients were examined by multislice spiral computed tomographic angiography (MSCTA), while 52 patients were examined by positron emission tomography/computed tomography (PET/CT), and 49 patients were subjected to CT-guided transthoracic needle biopsy (CTNB). The sensitivity, specificity and diagnostic accuracy were compared between the three methods for the diagnosis of lung cancer. Results Confirmed by postoperative pathological examination, 29 patients were suffering from benign lesions (23.8%), and 93 were with malignant lesions (76.2%). In the 85 patients with non-small cell lung cancer, only 56 (65.9%) were in early stage (Ia), and in 12(14.1%) hilar and mediastinal lymph node metastases were found. The sensitivity, specificity and diagnostic accuracy was 80.3%, 81.7% and 75.9% by MSCTA, 84.6%, 86.5% and 80.1% by PET/CT, and 91.8%, 88.6% and 100% by CTNB, respectively. The specificity of CTNB was better than that of MSCTA (P=0.045), and no significant difference was found in other indexes between MSCTA, PET/CT and CTNB (P>0.05). Conclusions MSCTA can serve as the first choice for the non-invasive diagnosis of small peripheral pulmonary nodules. Surgical operation is necessary for suspected malignant lesions, and CTNB can be selectively performed in patients who are considered to have benign lesions. In order to improve the speed and accuracy in locating the pulmonary nodules during the operation, the CT imaging should be carefully reviewed before operation in order to identify the location of the lesion, and CTguided transthoracic needle biopsy could be done when necessary.

There are more prognostic factors affecting the patients with cerebral hemorrhage, including bleeding volume, bleeding site, cause of bleeding, and blood pressure regulation during acute phase. Among them, the regulation of blood pressure during acute phase is a man-controlled important factor. However, the ideal blood pressure level has not yet to he determined at present. Therefore, more clinical trials are needed to determine the exact time window of blood pressure management in patients with intracerebral hemorrhage during acute phase and the range of blood pressure control.

Objective:To analyze the advantages of the pressure-regulated volume control (PRVC) mode compared with the traditional continuous mandatory ventilation (CMV) mode about mechanical ventilation efficiency of ventilator.Methods: For the mechanical ventilation situations, the parameters of PRVC mode, V-CMV mode and P-CMV mode under same detecting conditions were tested by using gas analyzer, which based on the ventilation principle of PRVC mode. And then the differences between PRVC mode and CMV modes were analyzed. Results: PRVC mode can supply the almost same tidal volume, and provide lower pressure and higher compliance compare with the V–CMV mode under the same conditions. On the other hand, PRVC mode can supply more tidal volume and slightly higher compliance compare with the P–CMV mode under the same pressure.Conclusion: PRVC mode has combined with the advantages of CMV mode, and it can make sure the target tidal volume, at the same time, reduce the pressure of airway, and improve the compliance for circuit. It also can make the mechanical ventilation to got more efficiency and more safety.

OBJECTIVE:The bioassay and HPLC methods were established and compared for the determination of levofloxacin(Lev) in human plasma.METHOD:In bioassay,medium Ⅱ and staphylococcus aureus were used.The HPLC method was chromatographed with a mobile phase of methanol-0.02mol/L potassium dihydrogen phosphate solution (3∶7)，the sample was treated by adding 30% trichloroacetic acid to precipitate protein,and detected at 276mm.RESULTS:The average recovery of bioassay was within 95.90%～106.68%,the within-day and day-to-day precisions were below 6%.The average recovery of HPLC was within 97.24%～101.70%,the within day and day-to-day precisions were blow 5%.Lev tablets were given to 6 patients in two ways.Drug concentrations in plasma were determined by bioassay and HPLC assay,respectively,with no significant difference (P＞0.05).CONCLUSION:The bioassay was simple,cheap,time saving,and reliable.The HPLC method wsa rapid,sensitive,accurate.The two methods may be selected to use in actual conditions.

The essence of thinking was the procedure for processing information by knowledge in the frame of world view,which depending on the world view and the existing knowledge and information.The characteristic of traditional Chinese medicine (TCM) thinking was reflected by its unique world view.The world view of TCM thinking was natural view,holism concept and dialectic view,compared with modern scientific thinking mostly in reduction analysis.To develop TCM,the modern TCM thinking system was established through the reforming and innovating of TCM thinking characteristic based on preservation and promotion of them.