Objective To evaluate the efficacy of laparoscopic surgery combined with sanjiezhentong capsule for endometriosis. Methods Thirty-three cases of endometriosis who accepted conservative surgery were divided into 2 groups: 19 cases accepted treatment of sanjiezhentong capsule (sanjiezhentong capsule group, infertile patients were 9 cases) and 14 cases accepted goserelin (goserelin group, infertile patients were 8 cases ). The treatment of two groups were given drugs on the first day of menstrual onset after operation for 3 months. The effect, side effect and pregnant was compared after treatment. Results The total effective rate of sanjiezhentong capsule group was 73.7%( 14/19) and in goserelin group was 78.6%( 11/14), there had no statistically significant (P> 0.05). The pregnancy rate of secondary infertile patients in sanjiezhentong capsule group was 55.6%(5/9) and in goserelin group was 62.5%(5/8)(P> 0.05). The side effect was lower in sanjiezhentong capsule group than that in goserelin group. Conclusion Sanjiezhentong capsule is a safe and effective drug in treating post-operative endometriosis.

OBJECTIVE:To investigate the characteristics of ADR induced by psychotropic drugs in children and adolescent of our center,and to provide reference for clinical drug use. METHODS:ADR induced by psychotropic drugs in children and adoles-cent reported by our center from 2005 to 2015 were investigated and analyzed retrospectively. RESULTS:A total of 177 ADR were collected,of which the most cases were induced by antipsychotic drugs as risperidonal,olanzapine and quetiepine. The most com-mon ADR were central and peripheral nervous system disorders(117 cases,37.86%),followed by endocrine disorder(35 cases, 11.32%),heart rate and rhythm disorders(32 cases,10.35%)and liver and biliary system disorders(17 cases,5.50%). By the relative titer of haloperidol,most of ADR were induced by haloperidol with dose of 4 mg,6 mg and 8 mg once a day(34,29 and 53 cases). Most of cases occurred within a week(94 cases,53.11%). CONCLUSIONS:To develop and strengthen clinical applica-tion and ADR monitoring of psychotropic drugs in children and adolescents should be regarded as the key to ensure drug use safety.

OBJECTIVETo compare the effect on surgical indicators and functional outcome between preoperative skeletal traction and skin traction for adult femoral fracture and guide the choice of preoperative traction method of adult femoral fractures.

METHODSFrom February 2008 to September 2012, 68 patients aged greater than 18-year-old with femoral fractures were treated and randomly divided into two groups according hospitalization order,the odd with skeletal traction of tibial tubercle (group A) and the even with skin traction (group B). In group A, there were 25 males and 9 females with an average age of (36.3±9.9) years old,including 11 cases with transverse fracture, 15 cases with oblique fracture, 8 cases with spiral fracture. In group B, there 26 males and 8 females with an average age of (37.1±11.0) years old,including 10 cases with transverse fracture, 13 cases with oblique fracture,11 cases with spiral fracture. The operative time,blood loss,the number and amount of blood transfusion ,fracture healing time, hemoglobin, pain scores and functional scores between two groups were analyzed and compared. Results:All patients were followed up, the follow-up time was (33.5±6.5) months in group A, (31.3±7.5) months in groupB. In group A,the operation time was (108.8±14.2) min and the intraoperative blood loss was (383.1±117.1) ml and the postoperative blood transfusion was 14 cases and the blood transfusion was (350.0±122.5) ml and the average bone healing time was(15.0±3.3) weeks. In group B, the operation time was (111.6±12.7) min and the intraoperative blood loss was (392.0± 116.7) ml and the blood transfusion was 11 cases and the blood transfusion was(327.3±129.1) ml and the average healing time was (15.5±3.4) weeks. These obseration indicators had no significant difference between two groups. There was no significant difference between two groups in terms of Hemoglobin, the pain scores before and after traction, the femoral fractures efficacy score,knee function score and knee range.

CONCLUSIONPreoperative skeletal traction does not reduce surgery time, blood loss and pain and so on. The bone healing time and limb functional outcomes were also not significantly improved.

Adult ; Blood Loss, Surgical ; Bone and Bones ; surgery ; Dermatologic Surgical Procedures ; Female ; Femoral Fractures ; physiopathology ; surgery ; Fracture Fixation, Internal ; Fracture Healing ; Humans ; Male ; Middle Aged ; Preoperative Period ; Traction ; Young Adult

Objective: To investigate whether Shuxuening injection has a protective effect on myocardial injury in rats with cecal ligation and puncture(CLP)- induced sepsis. Methods: Thirty SD rats were randomly allocated to Sham group, CLP group and Shuxuening group (SXN group). In the Shuxuening group, Shuxuening injection was intraperitoneally injected at a dose of 1 mg(0.3 ml)/body weight 1 h before CLP challenge. The sham and CLP groups received an equal volume of saline injection (0.3 ml/kg) at the same time points. Six hours later, the blood samples were obtained from abdominal aorta to determine the contents of TnT, TNF-α, and IL-1β. Meanwhile, MDA contents and SOD activities in myocardial tissues were also tested and the pathologic changes of the myocardial tissue were observed by H-E staining. Results: Compared with CLP group, the serum contents of TnT, TNF-α, and IL-1β and myocardial tissue MDA were decreased in Shuxuening group; and the myocardial tissue SOD activities were significantly increased in Shuxuening group (P<0.05 or 0.01). Microscope observation showed that the degrees of myocardial congestion, edema, and inflammatory cell infiltration were greatly improved in the Shuxuening group compared with in the CLP group. Conclusion: Our results suggest that Shuxuening can protect against CLP-induced myocardial injury in rats, probably through scavenging free radical and inhibiting release of inflammatory mediators.

Aged ; Astragalus Plant ; adverse effects ; Drugs, Chinese Herbal ; administration & dosage ; adverse effects ; Humans ; Injections, Intravenous ; adverse effects ; Low Back Pain ; etiology ; Male ; Phytotherapy ; adverse effects

Adolescent ; Adult ; Aged ; Aged, 80 and over ; Blood Vessels ; injuries ; Child ; Child, Preschool ; Female ; Free Tissue Flaps ; blood supply ; Head ; surgery ; Humans ; Male ; Middle Aged ; Neck ; surgery ; Tissue Transplantation ; adverse effects ; methods ; Young Adult

Humans ; Lymph Nodes ; pathology ; surgery ; Neck Dissection ; methods ; Oropharyngeal Neoplasms ; pathology ; surgery

ObjectiveTo explore the surgical methods and its efficacy on severe chronic obstructive pneumonia disease (COPD) with spontaneous pneumothorax.MethodsClinical features and surgical efficacies of 16 cases of severe COPD were analyzed.Results No death occurred and all patients recovered and discharged.The lung function index including subjective symptoms,motor ability and endurance in 14 cases showed obvious improvement compared with those before combination of pneumothorax.Two patients improved to the level before surgery.ConclusionThe lung function index of patients with severe COPD and pnumothorax can be relatively less restricted and open-chest surgery should be performed as soon as possible.Linear nailing and simple lung volume reduction surgery are recommended to improve lung function,shorten operation time and reduce surgical risks.

OBJECTIVE: To study the preventive effect of Breviscapus Injection on the chronic hypoxic myocardium injury in rats and its mechanism. METHODS: Transmission electron microscope and biochemical analysis were used to assay the therapeutic effect of Breviscapus Injection in rat model induced by 4 week's hypoxia. RESULTS: The contents of malondialdehyde (MDA) and Ca(2+) in the homogenate of myocardial tissue of the hypoxic rats were significantly higher than those of the control rats. The activities of superoxide dismutase (SOD), nitric oxide synthase (NOS) in the homogenate of myocardial tissue and the plasmic NO levels of the hypoxic rats were significantly lower than those of the control rats. Breviscapus Injection reduced the contents of MDA and Ca(2+), and increased the levels of SOD, NOS and NO. Ultrastructural examination revealed that the injuries of the ultrastructure of heart in hypoxic rats were improved by treatment with Breviscapus Injection. CONCLUSION: Breviscapus Injection can effectively prevent and treat the hypoxia-induced myocardial damage. One of its mechanisms may relate to its adjusting NO level, anti-damaging of free radicals and inhibiting calcium overload.

Objective To investigate the relationship between occurrence of unexplained recurrent spontaneous abortion(URSA) and immune function of T lymphocytes. Methods T lymphocyte subsets and CD + 4 T helper subsets (including T helper 1 and T helper 2 cells) in peripheral blood from 30 cases with URSA and 24 healthy women (controls) were detected by enzyme-linked immunospot assay (ELISPOT). Results The percentage of CD + 4 positive T lymphocytes in URSA group was higher than that in the controls (60% vs 45%, P