Objective To explore the expert consensus on pediatric literature citation.Method By the method of bibliometrics,experts' citation from2009 to2012 were statistically analyzed with bibliometrics.Result 18 expert consensus articles were identified,of which16 have citations.The citation rate is 88.89％,with an average citation of 21.47.The sources are mainly journals; the cited articles are mainly in foreign language (65.73％); ; the price index is 57.30％.Conclusion Expert consensus citation is novel,mainly from periodicals,and primarily in foreign language.But the citation quality needs to be improved further.

Journals published by Chinese Medical Association are a group of leading journals in the medical field in China. To refine these journals, the authors recommended that promote doubleblind peer review should be applied, supplements may be omitted and the supervision mechanism needs to be improved.

0.05). After experimental cerebral hemorrhage for 4 hours of model group, blood pressure and P O 2 were obvious increased( P 0.05), but they were lower than model group at the meantime ( P

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0.05). The average total medical expense and the cost of hormone drugs in dexamethasone-treated group vs. budesonide-treated group were(1 258.73?131.04)yuan and(8.94?1.45)yuan, respectively vs.(1 385.39?175.61)and (167.28?24.86)yuan, respectively, showing significant differences between the two groups(P

Objective The purpose of the studies was to explore the elective ways to enhance the ability of routine rest To - 99m - sestamibi (MIBI) myocardial scintigraphy to assess myocardial viability during the percutaneous transluminal coronary angioplasty (PTCA ) in assessing viable myocwhium. Methods Three methods, (1) rest- nitroglycerine augment, (2) rest-gated, (3) rest-delayed 99mc - MIBI myocardial scintigraphies, were performed in 20,30 and 10 patients with coronary artery disease treated with coronary revascularization. Results The results showed that in evaluating viable myocardium, the positive predictive values for methods(1 )-(3) were 95. 9%,68. 5% and 84.1%,mepectively, the negative predictive values were 68. 2%, 90. 1% and 90.0%, respecihvely, the predictive accuracy rates were 82. 5%, 77. 3% and 87.2%. Conclusions The results indicate that identification of viable myocardium with 98mTc - MIBI can be effectively enhanced with methods (1) - (3); the 99mTc - MIBI myocardial scintigraphy can provide objective data for evaluating treatment effects by coronary revascularization.

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Objective To investigate the effects of pramipexole on serum cystatin C, antioxidant indexes and brain derived neurotrophic factor ( BDNF) in the treatment of patients with Parkinson’s disease.Methods Retrospective a total of 96 patients with Parkinson’s disease were collected and randomly divided into experimental group and control group with 48 cases in each group.Patients in the control group were treated by levodopa,patients in the experimental group were treated on the basis of the control group with pramipexole, movement and non-movement symptoms were assessed by unified Parkinson’ s disease rating scale ( UPDRS), the serum cystatin C, antioxidant indexes and brain derived neurotrophic factor levels were measured, and the clinical efficacy and adverse reactions were compared.Results The effective rate of the control group (68.75%) was lower than the experimental group (87.50%), with statistical significance (P<0.05); compared with the control group, the movement and non-movement symptoms of the experimental group reduced after treatment, after treatment the serum CRP, serum cystatin C decreased, serum BDNF increased, after treatment the glutathione (GSH), catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidate (GPX) levels increased, with statistical significance (P<0.05).Conclusion Pramipexole in the treatment of patients with Parkinson’s disease could reduce serum cystatin C, improve the levels of BDNF and antioxidant capacity, the effect is remarkable.

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Objective To investigate the gene point mutation in the dihydrofolate reductase thymidylate synthase (dhfr) gene of Plasmodium falciparum isolate from Yunnan Province strongly associated with pyrimethamine and cycloguanil resistance. Methods Nested PCR and restriction endonuclease digestion were applied to detect the gene mutation using dried blood filter paper collected from the fields in Yunnan Province. Results Different mutations were found in 4 amino acids at positions 16, 51, 108 and 164 of dhfr gene, particularly, Asn 108 and Ile 51, the mutaiton frequency being 94.1% and 90.1%, respectively. The frequency of the wild type genotype (3D7 type) Ser 108 appeared lower ( 9.1%) , while the frequency of the Ala 16 was high( 61.8%); the mutation type was very high, the ratio of HB3 type, 7G8 type/FCR3 type and Cambodian type was 1∶21∶7.5. Conclusion The investigation first demonstrated that Plasmodium falciparum Yunnan isolate dihydrofolate reductase thymidylate synthase gene(dhfr) at positions 16, 51 ,108 and 164 exhibited different degrees of point mutation. The frequency of mutation of the 7D8 type involved in pyrimethamine resistance was higher, while that of the FCR3 type involved in cycloquanil resistance was lower.