The effects of stretching, sport massage, light exercise (80% of the subjects' anaerobic threshold), and hot pack on the recoveries of work capacity and blood lactate (La) after strenuous exercise were compared with the resting recovery conditions. In each experiment for the four recovery strategies, twelve male physical education students participated as subjects. The subjects performed 5-s maximal effort cycle ergometer exercise bouts, repeated 8 times with 20-s rests (W 1) . A 33-min rest period was given after W 1, and then the same exercise as W 1 was performed again (W 2) . During the rest period (from 9 to 19min after W 1), one of the recovery strategies was practiced for 10min. The subjects also participated in a control experiment (rest recovery) on another day. Blood samples were taken from the earlobe to determine La. The rate of work capacity recovery was significantly higher than the control when stretching was performed, but no significant difference was observed in the recovery rate of La. The same tendency was also observed in the case of sport massage. In the case of light exercise, on the other hand, the recovery rate of La was significantly higher than the control, whereas the recovery rate of work capacity was not significantly different. Many of the subjects complained that the intensity of light exercise was too hard. No significant differences were found in the recovery rates of both work capacity and La by application of a hot pack. These results suggest that stretching and sport massage are effective for accelerating recovery of work capacity. Light exercise was not effective in this study. However, considering previous investigations which showed light exercise to be effective, it might be effective if an abequate work intensity is given. A hot pack is suggested not to be effective. No significant correlation was observed between the recovery rate of La and that of work capacity. Thus it seems that the recovery of work capacity is regulated by factors other than La.

  When subacute elderly patients are transferred from an acute hospital to a rehabilitation facility, the likelihood is that the environmental change will decrease the patients' ability to perform the basic activities of daily living (ADLs). In this study, we assessed the effects of the ambient changes on ADLs by the use of the Barthel Index, the reliability as well as validity of which is rated high for assessing the patient's fundamental ability. Our subjects consisted of the patients with hemiplegia who had undergone medical treatment of stroke and those who had been operated on for femoral neck fracture (FNF) in Toride Kyodo General Hospital. They were transferred to the convalescent rehabilitation ward (CRW) of Aida Memorial Rehabilitation Hospital, affiliated with our hospital. We compared the BI scores given to the patients by physical, occupational and speech therapists, when discharged from our hospital, and those scores given by nurses within one week after the patients moved to the CRW. Differences between BI scores given at Toride Hospital and those at the rehabilitation hospital averaged -5.9±16.0 points for stroke patients and -7.3±14.1 points for FNF patients. Spearman's rank correlation coefficient of BI scores in the acute hospital and in the CRW for stroke patients was 0.91 (p<0.001) and 0.69 (p<0.001) for FNF. There was no significant difference in changes in BI scores between stroke and FNF. However, there was a tendency for the patients' functional ability in daily living to be assessed lower in the FNF patients than in the stroke patients. This was probably because the former were older than the latter on the average. The average age of the FNF patients was 81.4 years and that of the stroke patients was 68.5 years.

With the help of my colleagues, I have been conducting epidemiological studies on biliary tract cancer (BTC), including gallbladder cancer (GBC) and extrahepatic bile duct cancer (BDC), in Japan and Chile for about 19 years. Clustered areas with high mortality rates, especially for female GBC were found to correspond with places or prefectures in Japan that were famous for rice production. The roles of known risk factors, such as gallstones and cholecystitis, were examined, but no single factor was implicated in the high mortality rates for GBC in these areas. A working hypothesis, called the “rice production hypothesis” was formulated; this initial hypothesis was replaced by a new multifactorial causation hypothesis: GBC is more likely to occur in individuals with a genetic susceptibility and a past history of gallstones or cholecystitis who are exposed to geographically specific environmental factors, such as agricultural chemicals. On the basis of various analytical studies, it is concluded that a certain agricultural chemical was responsible for the occurrence of GBC. At the time of writing, no evidence has been obtained to disprove our hypothesis. We have also conducted international collaborative studies in Chile, which has the highest mortality rate for GBC in the world. Bile from Chileans was found to have a higher mutagenic activity than that from Japanese subjects; Chileans with a history of constipation or a habit of consuming red chilli pepper had a high risk of developing GBC, if they also had gallstone(s). The presence of a regional difference in p53 mutagenesis was also observed.
seconds ; Gallstones ; Mortality Vital Statistics ; Cancer of Biliary Tract ; Spatial Distribution

In this report, I trace the life of Prof. Hidetsurumaru Ishikawa who laid the foundation for the present successful development of acupuncture and moxibustion and pursued medical practice based on scientific evidence.
Prof. Ishikawa was born in Toyama Prefecture. After graduation from Tokyo Imperial University, he moved to Kyoto Imperial University to work in Prof. Amaya’s laboratory.
For 4 years starting from 1908, he studied in Europe, mainly under Prof. M. Verworn at Gottingen University, but also briefly visited Prof. I. Pavlov in Petersburg and Prof. E. Starling and Prof. C. Sherrington in England. He learned much about the newest science at that time, and these experiences served as a backbone for his later scientific research.
After returning to Kyoto Imperial University as a professor of physiology, he developed the physiological sciences in Japan. Along with the progression of modern physiology, he came to recognize the need of a scientific approach to traditional medicine, especially acupuncture, as well as a psycho-physiological approach to analyzing human biological conditions.
In the field of neurophysiology, he is famous for a sensational debate against Prof. Kato, who was one of his favorite disciples, about the conduction of electric impulses in anesthetized nerve cells:decrement or decrementless?
After his retirement from Kyoto Imperial University in 1944, Prof. Ishikawa went to Tsu City as the head of Mie Prefectural Medical College, the predecessor of Mie University Faculty of Medicine and opened the department of acupuncture in the university hospital the following year. During the postwar occupation of Japan, the General Headquarters of the Allied Powers (GHQ) decided to prohibit Japanese traditional medicine, because at that time, the general condition of acupuncture and moxibustion therapy in Japan was far below Western standards.
Learning of the prohibition order, Prof. Ishikawa visited the GHQ over and over again to explain with his own data the scientific basis of acupuncture and to demonstrate the benefits of acupuncture to the GHQ medical officers. Probably due to accumulated strain, in 1949 Prof. Ishikawa had a stroke during a faculty meeting and died about 2 weeks later. Prof. Ishikawa was succeeded by his apprentice, Prof. Kyugo Sasagawa of Kyoto University, who organized the Japan Society of Acupuncture. The first conference was held at Kyoto University in 1953, and the society has been continuously developing to its present successful status.