1.Mental health and response to life events: a survey in immigrant medical professionals in Dongguan city
Chinese Journal of Health Management 2011;05(4):246-248
Objective To learn mental health,life events and stress response of immigrant medical professionals. Methods Symptom checklist ( SCL-90), Life event scale ( LES), and Coping questionnaire (CQ) were used for assessment. Results SCL-90 ( 135.95 ± 32. 56 ), Somatization ( 1.62 ± 0. 38 ),obsessive-compulsion ( 1.75 ± 0. 53), depression (1.66 ± 0. 55) ,anxiety ( 1.52 ± 0. 54), hostility ( 1.53 ±0.45) ,and psychoticism (1.45 ±0.46) were even serious in immigrant medical professionals (all P<0. 05). SCL-90 factor score was positively correlated with LES total score and LES factor score ( both P <0. 05 ). However, SCL-90 factor score was negatively correlated with problem-solving and coping style score of CQ (P < 0. 01 ). Conclusion As mental health and life event responses were concerned, more attention should be paid to the immigrant medical professionals.
2.Clinical Significance of Serum ECP and IgE in Children with Asthma
Journal of Medical Research 2006;0(12):-
0.05).Conclusions These results suggest that the level of serum ECP can reflect the inflammation in the bronchial tube and the activated state of eosincyte more sensitively than IgE.
3.Ethical Consideration about Family Members' Participation in Cancer Treatment Decision-making
Chinese Medical Ethics 2017;30(3):315-318
The defense for paternalism is based on that family members' decisions are usually beneficial for patients' best interests.However,this premise remains to be demonstrated.The moral theory of maintaining family members' interests challenged the ethical principle of respecting patients' autonomy,which believed that treatment decisions should be discussed by the whole family members.However,the principle of autonomy does not always dissever the relationship between individual and family members.It resorted East Asia family autonomy of Chinese traditional culture and emphasized on the value of objective goodness and family dependence.However,patients often do not play a proper role in families' decision-making.Besides,the Confucian bioethics also needs to provide more sufficient argumentation to deal with the relationship between subjective goodness and objective goodness.The unconditional acquiescence of family members' domination in decision-making is worthy reflecting in the current medical environment.
4.Effects of Bacille Calmette Guerin on immunological function of infants with bronchiolitis
Chinese Journal of Clinical Pharmacology and Therapeutics 2000;0(03):-
AIM:To approach the effects of Bacille Calmette-Guerin(BCG)on immunological function of infants with bronchiolitis in vitro. METHODS: The monocytes were segregated from the peripheral blood of infants with acute bronchiolitis and healthy infants as control. The cytokines of IL-10 and IL-12 were measured by ELISA after interfered with different concentrations of BCG in vitro. IL-4, produced by lymphocytes treated with the cultural supernatant of BCG-stimulated monocytes were determined by ELISA. Acute bronchiolitis infants and health children treated with normal saline were as control. RESULTS: BCG stimulated IL-10 and IL-12 production in a dose response manner in a certain concentration range. The higher level of IL-10 was observed when BCG concentration reached 50 ?L/mL, while IL-12 had no significant increase. The level of IL-4 was markedly decreased compared with pre-treatment (P
5.Global Health Ethical Reflection on Antibiotics Abuse
Chinese Medical Ethics 2017;30(4):412-416
The ambiguous diagnosis,the public's insufficient understanding of AMR and improper use of antibiotics in agriculture are the main reasons for accelerating antibiotic resistamce(AMR).At present,the main coping strategies are limited to technical means while lacking ethical consideration.The related ethical issues are,mainly,tensions of personal health interests and public health interests,the conflicts between agricultural development and human health benefits,the distributive justice,inter-generational justice.Understandings and addressing these issues rely on value judgments based on the moral theories.And then it will form an effective and reasonable antibiotic management solution which will help to deal with AMR fundamentally.
6.Effectiveness of application of case management for hypertension in the elderly
Yanping REN ; Ruowen HUANG ; Yali HAN
Chinese Journal of General Practitioners 2010;09(11):749-752
Objective To explore application of case management for hypertension in the elderly.Methods In total, 106 elderly patients with hypertension treated at outpatient and inpatient departments of the First Affiliated Hospital of Xian Jiaotong University were recruited during January to October 2007, and divided randomly into two groups, one with conventional management and the other with case management.Patients with conventional treatment accepted routine diagnostic and therapeutic procedures and were followed-up passively, and patients with case management accepted integrated therapy and active interview provided by a team with a cardiovascular specialist as core, were followed-up actively and their medical records were kept in files. Percentage of the patients with blood pressure lowered to meet criteria of effectiveness and their improvement in depression and anxiety status and quality of life were evaluated two years after management for the two groups. Results Percentage of patients with their blood pressure lowered to meet effective criteria increased significantly in both of the groups, from 32. 8% to 67.5% in patients with conventional management and from 33.7% to 83.4% in those with case management ( P = 0. 007 ),respectively. Scores of self-rating anxiety scale ( SAS) and self-rating depression scale (SDS) decreased in patients of the both groups, from 57 ± 10 and 56 ± 11 before management to 40 ±9 and 48 ± 10 after it,respectively in patients of conventional management ( P = 0. 032 ), and from 56 ± 10 and 57 ± 10 before management to 35 ±9 and 40 ± 9 after it ( P = 0. 008 ), respectively in those with case management; and scores of quality of life improved in patients of the two group, from 65 ± 13 before management to 85 ± 14 after it in those with conventional management, and from 64 ± 13 before management to 98 ± 14 after it in those with case management ( P = 0.017 ), respectively. Conclusions Case management is better for chronic diseases and recommended in management for the elderly with hypertension, which can improve their targets of blood pressure lowering, decrease their scores of SAS and SDS and improve their quality of life,with an integrated, in-depth, continuous management.
8.THE EXPRESSION OF APOPTOSIC GENES BCL-2,BAX AND FAS IN ENDOMETRIOSIS
Yunxia WANG ; Yali LI ; Jingxiang HUANG
Medical Journal of Chinese People's Liberation Army 2001;26(1):69-70
We examined eutopic,ectopic endometria and peritoneal fluid macrophages from 22 patients with endometriosis(EMS) and 14 women without EMS.To obtain evidence for the induction of programmed cell death,apoptotic cells were identified using a modified terminal deixynucleotidyltransferasebiotin nick end-labeling method(TUNEL).To evaluate cell death repressor activity,bcl-2,bax and fas genes expression was examined using immunohistochemical staining. The results showed that bcl-2 expression in eutopic,ectopic endometrium and peritoneal fluid macrophages with EMS was significantly increased compared with no EMS(P<0.01).Bax expression in eutopic,ectopic and peritoneal fluid macrophages with EMS was significantly decreased compared with no EMS(P<0.05). Fas expression in eutopic,ectopic endometrium was decreased compared with no EMS(P<0.05). The expression of apoptotic genes were different in eutopic,ectopic endometrium and peritoneal fluid macrophages from EMS and no EMS.Apoptotic rate in EMS was lower than no EMS,and its acceptance was decreased,which could bear implications for the growth and survival of ectopic endometrial tissue.
9.Research on the psychological health state, life events and coping style of non-native teachers in the Dongguan city
Lanzhen REN ; Yali HUANG ; Hongrong LI
Chinese Journal of Behavioral Medicine and Brain Science 2008;17(4):346-347
Objective To learn the psychological health state,life events and coping styles of teachers.Methods 376 teachers were assessed with Symptom checklist (SCL-90),Life event scale (LES) and Coping questionnaire (CQ).Results The analysis showed non-native teachers score of SCL-90(150.74±44.57),somatization(1.69±0.58),obsessive-compulsive(1.84±0.58),depression(1.77±0.60),anxiety(1.63±0.55),hostility(1.68±0.61) and psychoticism(1.54±0.48) factor were higher than the native(P<0.01).The concerned analyses showed non-native teachers score of SCL-90 was significantly positively related to LES score factor (P<0.01).Teacher score of SCL-90 was significantly negatively related to settle problem factor of CQ(P<0.01),and other factors of CQ was significantly positively.Conclusion The poor psychological health state and live emergency events of the non-native teachers should be pay more attention.
10.Research on the psychological health state,life events and coping style of the non-native policemen in the Dongguan city
Lanzhen REN ; Yali HUANG ; Hongrong LI
Chinese Journal of Behavioral Medicine and Brain Science 2009;18(10):925-926
Objective To learn the psychological health state,life events and coping styles of the non-native policemen.Methods Symptom checklist (SCL-90),Life event scale (LES) and Coping questionnaire (CQ) was tested to native policemen(n=238) and non-native policeman(n=136).Results Score of SCL-90 (159.68±50.46) ,depression(1.79±0.62) ,photic anxiety(1.54±0.63) ,addition items(1.82±0.59) factors in non-native policemen were higher than that in the native policemen,and there was significant deference(P<0.05).The concerned analyses showed non-native policemen score of SCL-90 was significantly positively related to LES total score and sub-scale factor (P<0.01,P<0.05).The non-native policemen score of SCL-90 was significantly negatively related to settle problem factor of CQ (P < 0.01),and other factors of CQ was significantly positively(P <0.O1).Conclusion The poor psychological health state and live emergency events of the non-native policemen should be pay more attention.