TheInner Canon of Huangdi originated from moral.In the aspect of knowledge, it advocatesthat the doctor should not teach bandits, selecting and teaching, upright character, open but not narrow;In terms of career pursuit, it advocatesthat the doctor should adopt and frequently ask, work hard and to be a good doctor;In the as-pect of ethics, it advocatesthatdoctor should cherish life, be meticulous;In terms of professional belief, it advocat-esthatdoctor should learn from the ancient, firmly believe that science, opposing superstition; TheInner Canon of Huangdi advocate consummate medical skillthe noble medical ethics, with far-reaching influence, become the ori-gin of Chinese medical ethics thought germinal, future generations of today′s high-quality professional talents of Chinese medicine has a very important guiding significance.

The increasing magnetic strengths used for magnetic resonance imaging (MRI) combined with a greater number of MRI patients with cochlear implants (CIs) raises possible safety issues.This paper reviews the interactions between MRI and CI,and assesses MRI compatibility and safety of CIs at 0.2,0.3,1.0,1.5 and 3.0 tesla (T).In a word,CIs represent a significantcontraindication to MRI.Only after careful evaluation of the individual risk and careful preparations can an MRI be safely performed.

Hemorrhagic transformation is a common complication after ischemic stroke, especially after thrombolytic therapy. Its disability and mortality are very high. Therefore, it limits the clinical application of thrombolytic therapy. This article reviews the types of hemorrhagic transformation, possible mechanisms and predictors after thrombolysis for ischemic stroke in order to provide reference for clinical treatment and research of ischemic stroke.

The core values of traditional Chinese medicine culture greatly correlate with the ideological and political education of medical students and they can be integrated.Based on the discussion of the relationship between traditional Chinese medicine culture and medical students' ideological and political education,this paper analyzed the significance of integrating traditional Chinese medicine culture into medical students' ideological and political education:it could help to cultivate college students' patriotic sentiments,sense of honesty,and professional ethics.In addition,it put forward concrete implementation paths:exerting regional advantages and creating characteristic brand of ideological and political education,enriching classroom teaching and innovating the ways of ideological and political education,strengthening cultural construction and strengthening the perceptual cognition of ideological and political education,highlighting typical demonstration and enlarging the positive influence of ideological and political education.

Objective To investigate the effect of tumor necrosis factor receptor 1 (TNFR1) in angiogenesis and neurogenesis during cerebral ischemia in mice.Methods Twenty-four wild-type and 24 TNFR1 knockout mice were randomly divided into either a sham operation group or a focal cerebral ischemia group (n =12 in each group).5-bromodeoxyuridine (BrdU) was injected intraperitoneally at day 3 after cerebral ischemia and sham operation.At day 7 and 28 after cerebral ischemia,the double-label immunofluorescence staining of glucose transporter-1(Glut-1)/BrdU was used to evaluate the angiogenesis surrounding the areas of infarction.A labeled BrdU was used to detect the neural stem cell proliferation in the subventricular zone.Double-labeled doublecortin (DCX)/BrdU and neuronal nuclei antigen (NeuN)/BrdU were used to detect the migration and survival of neural stem cells,respectively.Results Under the normal condition,there was no significant difference in angiogenesis and the number of BrdU-positive cells in the subependymal zone (SVZ) between the wild-type (418.000 ± 28.404) and TNFR1 knockout (528.000 ± 60.597) mice (t =-1.644,P =0.131).At day 7 after cerebral ischemia,the number of Glut-1/BrdU-positive cells in the TNFR1 knockout mice was significantly less than that in the wild-type mice (14.833 ± 2.182 vs.27.5 ± 4.209) (t =2.672,P =0.023),and the number of DCX/B3rdU-positive cells was also significantly less than that in the wild-type mice (163.000 ± 11.106 vs.257.168 ± 12.213) (t =5.705,P =0.000).At day 28 after cerebral ischemia,the number of NeuN/BrdU-positive cells in the TNFR1 knockout mice was significantly less than that in the wildtype mice (6.000 ± 0.577 vs.11.000± 1.571) (t=2.988,P=0.014).Conclusions TNFR1 may play a promoting role in the neurovascular reggeneration in late cerebral ischemia.

Objective:To probe the effect of prenatal ethanol exposure on the mitochondrial protein expression in fetal mouse cerebrum. Methods:Pregnant CD-1 mice were given 5.0 g/kg ethanol intragastrically from pregnant days (PD) 6-15. Fetal cerebral mitochondria were isolated on PD 18. The overall mitochondrial protein was applied to two-dimensional gel electrophoresis. Differentially expressed protein spots were cut off and identified by matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry. Activities of respiratory chain complex Ⅳ(72.3%?4.6% of control)and ATP synthase, and ATP content in the fetal cerebral cells were measured. Results:Expressions of some constructional and functional proteins were altered by in utero ethanol exposure. Activities of respiratory chain complex Ⅳ and ATP synthase (80.3%?5.1% of control)were both decreased. ATP content (67.9%?3.9% of control) in the cerebral cells was reduced in the in utero ethanol exposure fetuses. Conclusion:In utero ethanol exposure affects the mitochondrial protein expression of fetal mouse cerebrum, even in the tissue without obvious morphological malformations, which may be a possible mechanism of behavioral defects found in children with prenatal ethanol exposure.

Objective To evaluate the clinical diagnostic role of dental computed tomography (CT) and three-dimensional reconstruction (3DR) compared with conventional dental periapical radiography (DPR) in the diagnosis of molar furcation involvement (FI). Methods Dental CT and 3DR were performed about a maxillary first molar and its alveolar bone diagnosed as FI II? by conventional probe technique, and the images were compared with that of DPR. Results The images of dental CT scans and 3DR showed not only the area, type and quantity of periodontal destruction, but also the complex stereoscopic anatomical vision and ambient spatial relationship around the molar. Especially, the images displayed the alveolar destructions of the dental buccal and palate site that could not always be demonstrated by DPR. The degree of the molar FI was defined as III? in fact. Conclusion Dental CT and 3DR have many superiorities and value, which can not be replaced by DPR, in the clinical diagnosis and prognostic judgment of molar furcation involvement.

OBJECTIVE： To develop a method of thin－ layer chromatographic scanning to determine the content of puerarin in Jiangtang pill METHODS： Silica GF254 thin－ layer was used， and the mobile phase consisted of chloroform－ methanol－ water(7∶ 2 5∶ 0 25) with the detection wave－ length of 254nm and the control wave－ length of 370nm RESULTS： The linear range of puerarin was 0 4～ 2 0μ g The mean recovery was 99 40％ (n=5) with RSD of 1 37％  CONCLUSION： This method is accurate， reliable and can be used for the determination of puerarin in Jiangtang pill

ObjectiveTo investigate relationship between the degree of placenta praevia, vaginal bleeding and clinical outcomes. MethodsRecords of 89 patients with placenta praevia(mild praevia group 43; severe praevia group 46) were reviewed retrospectively, and outcomes were compared. ResultsThe gestational age at the first bleeding and diagnosis was significantly smaller in severe group than that in mild one (P<0.05). The incidence of antepartum haemorrhage, the times of bleeding and the episodes of heavy bleeding in two groups showed no significant differences(P>0.05). The gestational age at diagnosis and delivery and birthweight were significantly smaller in women with antepartum bleeding than in those without( P<0.01 ). The number of deliveries by emergency caesarean section in women with antepartum bleeding was significantly higher than that in those without (P<0.01). ConclusionThe clinical outcomes of placenta praevia are highly variable. There are no obvious clinical features that are typical in predicting the clinical outcomes. The number of bleeding episodes and the degree of praevia are not associated with outcomes, so they can't be the proof to determine the treatment plan ahead of time.