1.Analysis of Ifected Instances By Hp of Civil Servant in Beijing
Yajie YU ; Qiuhong YU ; Yingwei OU
Journal of Medical Research 2006;0(04):-
Objective To observe the infected instances of civil servant by Hp in Beijing and study the relationship between Hp and age,sex.Methods 3275 people were divided into four groups based on age:yong group,midlife group,pre-agedness group and agedness group;each group based on sex were divided into two groups.Every one was detected by 13C-urea breath test.If the resalt is over four,it is positive,otherwise it is negative.Measure dates were analised by statistical software.The infecting rate of Hp is denoted by persent,Chi square test was used in the every group.Results The mean infecting rate of Hp was 41.47%.The women in midlife group was 46.02%,it is the highest.The men over 75 in agedness group was 38.48%,it is the lowest.The infecting persent of yong group was higher than that of agedness group.The persent of midlife group and pre-agedness group was meaning result.The difference in age and sex had no statistical meaning.Conclusion The infecting rate of civil servant by Hp in Beijing is obviously lower than of people in Beijing,which is no relationship with sex and age.
2.Determination of L-Carnosine in Polaprezine Granules by HPLC
Yali WANG ; Hongling YU ; Yajie BAO
China Pharmacy 1991;0(01):-
OBJECTIVE:To develop an HPLC method for the determination of L-Carnosine in Polaprezine granules.METHODS:The Chromatographic column was Agilent ODS with detection wavelength of 215 nm and flow rate of 1 mL?min-1.The mobile phase consisted of sodium subsulfite buffer solution(pH=3)-acetonetrile(77:23).The column temperature was set at 30 ℃ and injection size was 10 ?L.RESULTS:The good linearity was obtained in the range of 0.1559~3.1584 ?g for L-Carnosine(r=1.0000).The average recovery was 99.65%(RSD=0.078%).CONCLUSION:The method is simple,accurate and sensitive,and it is suitable for content determination of L-Carnosine in Polaprezine granules.
3.Culture construction in college and university medical library
Xue YU ; Zhangyi QU ; Yajie LI
Chinese Journal of Medical Library and Information Science 2014;(2):38-40
After the culture in college and university medical library was described, the necessity of its construc-tion was elaborated, and its implementation measures were stressed, such as setting up experience area, bringing into play of Primal interactive 3D anatomical database, planning subject activities according to the health holidays, providing personal space for users based on library websites, effectively popularizing reading, consecutively expan-ding service space, and carrying out personal service.
4.Construction and Practice of Teaching Evaluation System of PBL Mode in Clinical Pharmacology
Ji HAN ; Yu LIANG ; Yajie XU ; Mingyan JIANG
China Pharmacy 2015;(18):2583-2585
OBJECTIVE:To establish an overall teaching evaluation system for clinical pharmacology with PBL(problem-based learning) mode. METHODS:The teaching evaluation system was established by“Delphi”method,and it has been applied to 270 students at China Medical University in 2013-2014. RESULTS:According to the result of test score,PBL method can improve abil-ity of analyzing medical records,while formative evaluation indicates most of the students are satisfied with class response.And PBL method also can enhance student’s skill of clinical practice,broaden the knowledge an so on. CONCLUSIONS:The evaluation sys-tem was comprehensive with contents,systematic and objective,and it also can provide an effective feedback in teaching,which can accelerate the optimization of the teaching mode and improve the quality of education.
5.THE EXPERIMENTAL STUDY ON THE ABSORPTIOM OF IRON IN ~(59)Fe-ENRICHED NUTRIENT YEAST
Shumin MA ; Baogui WANG ; Yan HOU ; Yajie ZHANG ; Liping YU
Acta Nutrimenta Sinica 1956;0(01):-
The absorption of 59 Fe incorporated into yeast was studied in rats. Yeast was cultured in a nutrient solution to which radioactive 59Fe was added as an intrinsic tag. The 59Fe-enriched yeast was separated from the solution by centrifuge and given to rats by a stomach tube. The rats of the control groups were given the radioactive " Fe together -with ordina-ly yeast plus ferrous sulfate or only with ferrous sulfate separately.All feces were collected until less than 0.5 per cent of the administered dose was present in a 24-hour specimen of feces. The radioactivity in the feces was then measured daily for three successive days. The absorption of iron was calculated by the difference between intake and fecal loss.The result revealed that the absorption of iron in "Fe-enriched yeast (38.7%) was similar to that of ferrous sulfate (38.3%). It indicated that the iron incorporated into yeast was easily to be absorbed.This study afforded the scientific data for researching and popularizing fortified food with iron-enriched yeast.
6.Determination of Antibacterial Effect of Ofloxacin Eye Drop
Hao LI ; Yu ZOU ; Fan ZHANG ; Yajie ZHANG
China Pharmacy 2017;28(6):841-843
OBJECTIVE:To establish a method for the determination of antibacterial effect of Ofloxacin eye drop. METH-ODS:According to the requirements in Chinese Pharmacopoeia(2015 edition)antibacterial effect test,using Staphylococcus au-reus,Pseudomonas aeruginosa,Escherichia coli,Aspergillus niger and Candida albicans as test bacteria,colonycount method suit-ability test was conducted for Ofloxacin eye drop samples,the verified method was used to determine the number of viable bacteria at each time point,calculate the bacteria number of 1 mL in the sample and the number of bacteria at each time point and convert to lg value. RESULTS:Ofloxacin eye drop sample can reach the standard of antibacterial effectiveness of theB. CONCLU-SIONS:The method can effectively determine whether the antibacterial effect of Ofloxacin eye drop fits the standard.
7.Effects of Qinma Formula on Inflammatory Cell Related Factors in Rats with Chronic Obstructive Pulmonary Disease
Yajie DING ; Xiao CHEN ; Zhongyi YU ; Chunpu ZOU
Chinese Journal of Information on Traditional Chinese Medicine 2017;24(9):55-58
Objective To investigate the effects of Qinma Formula on endogenous anti-inflammatory system in rats with chronic obstructive pulmonary disease (COPD); To discuss its mechanism of action. Methods Rat models of COPD were made by modified smoked lipopolysaccharide method. 70 healthy SPF male Wistar rats were randomly divided into normal group, model group, Western medicine control group (aminophylline group), TCM medicine control group (Liujunzi Decoction group) and Qinma Formula high-, medium-, and low-dose groups, with 10 rats in each group. Each medication group was given relevant medicine for gavage. The pathological changes of lung tissue were observed under light microscope; the alveolar lavage fluid (BALF) and venous blood were collected and the related indexes were tested; the levels of serum IL-1β, IL-6 and IL-10 were detected by ELISA. Results Compared with normal group, BALF white blood cells, neutrophils, macrophages, lymphocyte, hemoglobin and platelet count in rats of model group increased significantly (P<0.05). Compared with the model group, BALF white blood cells, neutrophils, and macrophages in rats of Qinma medium- and high-dose groups and Liujunzi Decoction group decreased significantly (P<0.05); white blood cells, hemoglobin, and platelet count in rats of Qinma medium-, high-dose groups and aminophylline group decreased significantly (P<0.05); levels of IL-1β and IL-6 in serum decreased significantly (P<0.05); level of IL-10 in serum increased significantly (P<0.05). Conclusion Qinma Formula can effectively inhibit the inflammatory response through the regulation of inflammatory response-related cytokines.
8.Influencing factors of self-resolved mechanism of medical disputes and recommendations
Yu LIU ; Liangyu WEI ; Jianqiang CHEN ; Jie CHEN ; Yajie HU ; Lei WANG
Chinese Journal of Hospital Administration 2011;27(4):282-284
The unsatisfactory operation of the existing mechanism for resolving medical disputes by doctors and patients may be contributed to the instability of this mechanism, as lack of regulation constraints results in huge discrepancies of outcomes between identical cases. Specifically, the uncertainty for doctor-patient consultation in the guidelines, evaluation and decision mechanism,consultation process, and compensation calculation. In this consideration, it is recommended to elevate the mechanism stability of this consultation by means of uniform guidelines, third-party evaluation and decision, standardized consultation process, and unified compensation standard.
9.Relationship between resilience and coping style of cardiac valvular postoperative patients with cardiopulmonary bypass
Wenhong XIE ; Yajie LI ; Yan YU ; Mei LI ; Yongyi PAN ; Kangxing LIN ; Suhua ZHUANG
Chinese Journal of Practical Nursing 2013;29(36):42-45
Objective To explore the relationship between resilience and coping style of cardiac valvular postoperative patients with cardiopulmonary bypass.Methods A total of 208 cardiac valvular postoperative patients with cardiopulmonary bypass were recruited from 4 cardiovascular surgery in Guangdong and were investigated with the self-designed questionnaire,Connor-Davidson Resilience Scale (CD-RISC),Medical Coping Modes Questionnaire (MCMQ).Results The average score of resilience in cardiac valvular postoperative patients with cardiopulmonary bypass was (55.38±10.63)points.The average score of tenacity,strength and optimism were (28.21 ±5.87)points,(18.21 ±4.02)and (8.96± 1.85)points respectively.The average score of coping style of confrontation,avoidance and acceptance-resignation were(18.13±3.38),(16.95±1.75)and (9.24±2.47)points respectively.All the sub-scores of the resilience were positively correlated with confrontation,and all the sub-scores of the resilience were negatively correlated with avoidance and acceptance-resignation.Conclusions There is a certain degree of correlation between resilience and copping style of cardiac valvular postoperative patients with cardiopulmonary bypass.Nurses should enhance resilience of the patients,guide the patients to adopt effective coping styles,to promote disease rehabilitation and improve the quality of life.
10.Risk factors for occurrence of post-sustained virologic response hepatocellular carcinoma in chronic hepatitis C ;patients
Qinglei ZENG ; Jun LYU ; Yanling FU ; Yanmin LIU ; Yajie PAN ; Zujiang YU
Chinese Journal of Infectious Diseases 2016;34(3):160-165
Objective To investigate the risk factors and predictive model for the occurrence of post-sustained virologic response (SVR)hepatocellular carcinoma in chronic hepatitis C (CHC)patients. Methods A total of 203 CHC patients hospitalized at the First Affiliated Hospital of Zhengzhou University from January 2006 to December 2014 who received antiviral therapy and achieved SVR were collected,including 11 post-SVR HCC cases.Risk factors for post-SVR HCC were estimated by Cox′s proportional hazards regression model.Cutoff value predicting risk of post-SVR HCC was determined by receiver operating characteristic curve.Results In Cox′s model,the risk of post-SVR HCC increased by 9.4-fold in patients with initial diagnosis as compensated cirrhosis compared to those with initial diagnosis as CHC.Increase in post-SVR albumin by per 1 g/L was associated with reduced risk by 20% for the occurrence of post-SVR HCC.Cut-off value of post-SVR albumin for the prediction of HCC was determined as ≤ 36.0 g/L with an area under the curve (AUC)of 0.809.A predictive model for post-SVR HCC was created based on initial diagnosis as compensated cirrhosis and post-SVR albumin ≤36.0 g/L with an AUC of 0.871 .The sensitivity,specificity and negative predictive value of the model were 0. 818,0.896 and 0.989,respectively.Conclusions Initial diagnosis as compensated cirrhosis combines with post-SVR albumin ≤36.0 g/L are risk factors for post-SVR HCC with ideal prediction value for the occurrence of post-SVR HCC in CHC patients.