1.Kangfuxin Liquid combined with conventional treatment for infantile herpetic stomatitis
International Journal of Traditional Chinese Medicine 2016;38(5):417-419
Objective To evaluate the clinical effect of buccal administration of Kangfuxin Liquid combined with conventional treatment for infantile herpetic stomatitis. Method A total of 103 infantiles with herpetic stomatitis were randomly divided into a Kangfuxin group (51 cases) and a conventional group (52 cases). The conventional group received ribavirin aerosol, and the Kangfuxin group recived buccal administration of Kangfuxin Liquid based on the intervention of convertional group. All children were treated for 5 days. The white blood cell count (WBC) and the serum C-reactive protein (CRP) were determined. Result The total efficiency rate in the Kangfuxin group was significantly higher than that in the conventional group (94.1% vs. 78.8%,χ2=3.895, P<0.05). The healing time of oral ulcers (5.8 ± 1.3 d vs. 7.9 ± 1.5 d, t=10.715), body temperature recovery time (2.1 ± 1.1 d vs. 3.3 ± 1.5 d, t=4.623), and eliminating time of oral mucosal hyperemia and edema (4.3 ± 1.3 d vs. 5.3 ± 1.4 d, t=3.755) in the Kangfuxin group was significantly shorter than those in the conventional treatment group (P<0.01). The WBC (6.5×109 ± 2.2×109/L vs. 9.4×109 ± 2.3×109/L, t=6.537) and serum CRP levels (6.7 ± 1.2 mg/L vs. 9.7 ± 2.5 mg/L, t=12.686) were significantly lower in the Kangfuxin group was significantly lower than those in the conventional treatment group (P<0.01). Conclusions The total efficiency rate of buccal administration of Kangfuxin Liquid combined with conventional treatment for infantile herpetic stomatitis was higher than conventional treatment alone. And the remission time of symptoms of treatment group was shorter.
2.Application of the trans-theoretical model on the behavior of foot serf-care in patients with type 2 diabetes
Liping WU ; Yajie LI ; Zhuiqin ZHANG
Chinese Journal of Nursing 2009;44(12):1086-1089
Objective To explore the effects of trans-theoretical model on the behaviors of foot serf-care in patients with type 2 diabetes mellitus.Methods One hundred and twenty patients with type 2 diabetes were recruited from a community in Guangzhou.The patients were randomly divided into control group (routine diabetic foot education) and experimental group (intervention based on tram-theoretical model of behavior change).Result Repeated Measures ANOVA showed that the main effects of intervention and time,as well as the interaction effect between intervention and time were all significant (P<0.05).The incidence rates of the chap of foot skin,paronychia and destruction of foot skin were significantly different between the two groups (P<0.05),while no significant difference on the incidence rate of foot ringworm was found (P>0.05).Conclusions The application of tram-theoretical model can promote the improvement of foot self-care behaviors and thereby to improve the condition of foot skin in patients with type 2 diabetes.
3.Expression of PACE4 in non-small cell lung cancer and analysis of its clinicopathologic characteristics
Yunen LIN ; Qinian WU ; Yajie ZHANG
Journal of Chinese Physician 2015;17(10):1474-1476
Objective To investigate the expression of paired amino acid cleaving enzyme 4 (PACE4) protein in non-small-cell lung cancer (NSCLC), analyze the correlation of its clinicopathologic characteristics, and investigate its significance in the process of occurrence, development, and metastasis of NSCLC.Methods Between January 2006 and May 2009, the First Affiliated Hospital of Guangzhou Medical College, 172 patients with NSCLC and 15 patients with non-neoplastic tissues were chosen.Immunohistochemistry was used to detect the expression of PACE4, and clinicopathologic characteristics of NSCLC were analyzed.Results (1)The positive expression rate of PACE4 protein in NSCLC was significantly higher than that in non-tumor tissues (P < 0.05).PACE4 expression was observed in 111 of 172 (64.5%) NSCLC.PACE4 had cytoplasmic expression.(2)Clinicopathologically, PACE4 expression was significantly associated with lymph node metastasis (N stage) (P =0.007), and clinical stage (P =0.024).Conclusions High expression of PACE4 indicates that PACE4 may be involved in the processes of occurrence,development, and metastasis of NSCLC.
4.Efficacy of low-frequency rTMS to the right frontal cortex for depression:a meta-analysis
Yajie LU ; Lin XIA ; Shengjun WU
Chinese Journal of Nervous and Mental Diseases 2015;(6):341-348
Objective To systematically assess the efficacy of the low-frequency repetitive transcranial magnetic stimulation (rTMS) to the right frontal cortex for depression. Methods Clinical randomized controlled trials (RCT) studies about low-frequency rTMS to the right dorsolateral prefrontal cortex (DLPFC) for depression were collected from database such as PubMed, SCI, CBM, CNKI, and VIP. The meta-analysis using the software of RevMan 5.2 was conducted to com?pare the response rate of low-frequency rTMS to the right DLPFC with sham stimulation and high-frequency rTMS to the left DLPFC, respectively. Results Nine RCT studies with 156 patients in low-frequency rTMS group and 162 patients in sham stimulation group were included. Meta-analysis showed that low-frequency rTMS to the right DLPFC significantly improved response rate compared with sham stimulation(RR=2.15,95%CI:1.57~2.95,P<0.01). Eleven RCT studies with 178 patients in low-frequency rTMS group and 200 patients in high-frequency group were included. There was no significant difference in response rate between the two groups(RR=0.80,95%CI:0.63~1.02,P=0.07). Conclusion The efficacy of low-frequency rTMS to the right frontal cortex for depression is significant but the efficacy is not superior in comparison with the high-frequency rTMS to left DLPFC.
5.Incidence of gastro-esophageal and-hypopharyngeal reflux during gynecological laparoscopy: laryngeal mask vs tracheal tube
Yajie WEN ; Changbin WU ; Jinkun LIN
Chinese Journal of Anesthesiology 1997;0(11):-
Objective To compare the incidence of gastro-esophageal and -hypopharyngeal reflux during gynecological laparoscopy performed under general anesthesia and mechanical ventilation with tracheal intubation (TT) and laryngeal mask airway (LMA) .Methods Sixty ASA Ⅰ or Ⅱ patients aged 18-60 yrs with BMI 0.05 ) . Conclusion In low risk patients the incidence of gastro-esophageal regurgitation is comparable in patients undergoing gynecological laparoscopy in head-down position under general anesthesia and mechanical ventilation using either LMA or TT.
6.Artificial cycle therapy of acupuncture and moxibustion for irregular menstruation.
Jie WU ; Lijie YANG ; Yajie CHEN ; Qing LI ; Lin CHEN
Chinese Acupuncture & Moxibustion 2015;35(3):287-289
Through the discussion on TCM physiological characters of females in follicular, ovulatory, luteal and menstrual phases and treatment principles, the clinical application of artificial cycle therapy of acupuncture and moxibustion was introduced for irregular menstruation and the typical cases were attached. It is suggested that the menstrual cycle follows the growth-consumption rule of yin, yang, qi and blood. The corresponding treatment principles should be applied in accordance with the change rule of menstrual cycle. Hence, it is worth to adopt the artificial cycle therapy of acupuncture and moxibustion for irregular menstruation in clinical application.
Acupuncture Therapy
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Adult
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Female
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Humans
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Menstruation
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Menstruation Disturbances
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physiopathology
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therapy
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Moxibustion
7.Application of six-bar mechanism in the design of knee joint prosthesis
Genglin ZHANG ; Haljuan DING ; Dong WANG ; Yajie WU
Chinese Journal of Tissue Engineering Research 2008;12(44):8762-8764
This paper validated the centrode of six-bar mechanism was similar to circle center curve for different bending radius of the lemur, and introduced the gait analysis of knee joint of six-bar mechanism in normal movement t oprovide theoretical design foundation for developing a new knee joint.
8.Design of portable 12-lead digital ECG with low power consumption.
Chuanguang SHENG ; Cuiwei YANG ; Xiaomei WU ; Yuanyuan WANG ; Yajie QIN
Chinese Journal of Medical Instrumentation 2013;37(6):417-420
The design of portable and low power consumption 12-lead ECG is based on the digital signal processor TMS320C5515 and the analog front end ADS1298. The ADS1298 collects the ECG signals and deliver them to TMS320C5515. The preprocessed ECG signals are displayed real-time on a LCD and can be stored without compression for a long time. The ECG signals can also be sent to an up computer by a USB connector so that ECG data can be analyzed offline. The system has small volume, high precision and low power consumption.
Electrocardiography, Ambulatory
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instrumentation
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Equipment Design
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Signal Processing, Computer-Assisted
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instrumentation
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Software Design
9.Clinical observation on the differences of liver function indexes in acute left heart failure and congestive heart failure
Jianyan WEN ; Xiaoyan WU ; Yajie CHENG ; Wencong ZHOU
Chinese Journal of Biochemical Pharmaceutics 2017;37(3):298-300
Objective To compare the differences of liver function indexes in patients with acute left heart failure and congestive heart failure , and to provide the basis for the diagnosis of heart failure .Methods 142 cases of heart failure from March 2014 to December 2015 in our hospital were selected and divided into 68 cases of acute left heart failure group and 74 cases of congestive heart failure group.The differences in liver function tests were compared between the two groups by comparing the differences in the indexes of heart failure, liver blood biochemistry, general biochemical indexes and late follow-up data.Results Compared with the indexes of heart failure, there were no significant differences in ejection fraction, NT-proBNP, history of heart failure>one years, and the number of patients with right heart failure, the difference was statistically significant (P<0.05).Comparison of liver blood biochemistry: patients with acute left heart failure were alanine aminotransferase, aspartate amino transferase, albumin increased, the difference was statistically significant (P<0.05), and glutamyl aminotransferase, total bilirubin, direct bilirubin, indirect bilirubin decreased, the difference was statistically significant (P<0.05).There was no significant difference between the two groups of patients with alkaline phosphatase and total protein.Compared with the general biochemical indexes, increased triglyceride levels in patients with congestive heart failure group, the difference was statistically significant (P<0.05), there was no significant difference in other indexes.Conclusion AHF patients with ALT, AST increased, CHF with GGT, TBIL, DBIL, IBIL increased, ALB decreased mainly.
10.Clinical effect of endovascular stent placement on intracranial internal carotid artery dissection therapy
Sixin WANG ; Wu ZHOU ; Xiongjun HE ; Kaifeng LI ; Yajie LIU
Clinical Medicine of China 2013;29(z1):104-107
Objective To evaluate the clinical effect of endovascular stent placement to the treatment of intracranial internal carotid artery dissection.Methods Two patients with intracranial internal carotid artery dissection received the treatment of stent placement,and 1 patient with a dissection of the supra clinoid internal carotid artery received conventional anticoagulation treatment.Results Two patients with intracranial internal carotid artery dissection were given treatment of Apollo stent placement,of which 1 patient had improvement of left limb paresis,the score of NIHSS from 3 before operation to 2 after operation; the other one with episodic left limb weakness was not seen any attack after stent placement.Another one patient without stent placement receiving conventional anticoagulation treatment had some improvement of right limb paralysis.Conclusion The treatment of endovascular stent placement to the intracranial internal carotid artery dissection has better clinical efficacy and especially used for those patients with no effect to the conventional anticoagulation treatment.