Objective To study the effect and adverse reaction of lactulose oral solution on the treatment of postpartum constipation.Methods A total of 120 patients with postpartum constipation were randomly divided into treatment group (n=61) and control group (n=59).The treatment group received 15 mL lactulose oral solution,twice a day.The control group received wheat cellulose particles 3.5 g,twice a day.After the improvement of symptoms,the patient''s medication frequency was changed to 1 time a day,the course of treatment was 2 weeks long.The curative effect(including before treatment,period during the treatment,and the first week after finish the whole treatment) and the recurrence of constipation after treatment were observed.Results The frequency of defecation per week in the treatment group was(3.83±1.61)times,that in the control group was(3.09±1.53)times at the first week after treatment(P<0.05),those were(6.22±1.96)and(5.15±1.71)times respectively in the second week(P<0.01),and (6.43±1.87),(5.29±1.64)times respectively at the first week after treatment(P<0.05).The total recurrence rate in the two groups were 4.92% and 10.17% respectively(P>0.05) after follow-up to 60 d.The degree of drug acceptance in two groups was 100.00% and 76.27% respectively(P<0.01).There was no obvious adverse reaction in both two groups.Conclusion The effect of lactulose oral solution on the treatment of postpartum constipation is definite and with low recurrence rate.Lactulose oral solution has a good taste,easily to be taken and to be accepted,it is worthy of clinical application.

Generalized anxiety disorder (GAD) is one of the most common anxiety disorders.However,the diagnosis of GAD is difficult,GAD has the lowest diagnostic reliability among anxiety disorders and is often neglected.This article reviews the application of the General Anxiety Disorder-7 (GAD-7) in population screening for GAD,focusing on its history of development and the scope of unilization.

Objective To survey the status of generalized anxiety disorder (GAD) among disabled people in Shanghai Jing'an district and to investigate the influencing factors.Methods A cross-sectional study was conducted in January to March 2016 among the disabled residents in Shanghai Jing'an district.The general information was collected with questionnaire;the GAD status was rated with the Chinese version of 7-item Generalized Anxiety Disorder Scale;the influencing factors related to GAD was examined with Logistic regression analysis.Results Among 1 417 participants there were 713 males (50.3％) and 704 females (49.7％).The highest proportion of disability was disabled limb (n=742,52.4％).The grade 4 disability (mild) accounted for 45.9％ (650/1 417),and the grade 1 and 2 disability (severe) accounted for 13.6％ (190/1 417) and 15.2％ (212/1 417),respectively.There were 347 participants positive for GAD screening (GAD≥5) with a positive rate of 24.5％:24.3％ for males and 24.1％ for females (x2=0.007,P=0.960).The rates of mild,moderate and severe GAD were 19.1％,3.5％ and 1.1％,respectively.Multi-factor analysis showed that subjects with severe disability (vs.mild disability,/β=0.575,P=0.003),those unable activities of daily living (ADL) (vs.normal ADL,β=0.034,P=0.000)were nore likely to lead to GAD.There was a lower risk of GAD for people with high school or junior college education than those with bachelor degree or above (P＜0.05).The frequency of GAD in the disables aged 18-40 years was lower (P＜0.05).Conclusion The GAD positive rate of disabled people in Shanghai Jing'an district is relatively high.Severe disability,ADL disorder,educational level and age are the factors affecting the prevalence of GAD.

Objective To survey the quality of life of disabled people in Shanghai Jing'an district and to analyze the influencing factors.Methods A face-to-face interview was conducted among 1 831 disabled people from 5 communities of Jing'an district between September 2015 and January 2016.The quality of life was evaluated with Modified Barthel Index (MBI),12-Item Short Form Health Survey (SF-12) and Patient Health Questionnaire (PHQ).Results There were 941 males and 870 females among 1 815 qualified participants.There were 433 cases of visual disability (23.86％),222 cases of hearing disability (12.23％),20 cases of language disability(1.10％),742 cases of limb disability (40.88％),169 cases of intelligent disability (9.31％),198 cases of mental disability (10.91％) and 31 cases (1.71％) of multiple disabilities.The SF-12 showed that the mean scores of both physical aspect and mental aspect were 50.0 ± 10.0.Multiple linear regression showed showed that the low self-care ability of daily life (β =0.24,P =0.00),depression (β =-9.65,P =0.00) and high serum lipids (β =-2.36,P =0.02) were associated with the quality of life.Conclusion The study indicates that the quality of life of the disabled people in Jing'an district is generally low,which is affected by various factors.