Objective To investigate the curative effect of DrafⅠtype,Ⅱa/b-type frontal sinus drainage used on 42 patients(75 sides)with prosopantritis.Methods A summary analysis of 42 patients(75 sides)with prosopantritis who lined DrafⅠtype,Ⅱa/b-type frontal sinus drainage according to dissect characteristics during January 2011 to October 2012.Results CT of the 42 patients shows that there are 75 sides with prosopantritis,Based on the analysis of anatomical features performed DrafⅠtype,Ⅱa/b-type frontal sinus drainage to these patients,efficiency was 82.67%.Follow-up in half a year,restenosis and atresia again of 21 sides frontal sinus ostium was found.Conclusion Draf drainage has a good curative effect with small creation,few bleed and few recur-rence in chronic prosopantritis.

Objective To investigate the curative effect of Suhuangzhike capsules and Desloratadine Citrate Disodium used in chronicity allergic pharyngits .Methods Branched 147 patients into two sets ,the observation group with 85 patients treated with Suhuangzhike capsules and Desloratadine Citrate Disodium ,the control group with 62 pa-tients treated with Desloratadine Citrate Disodium only .Results The total effective rate of the observation group was 97.6%.The total effective rate of the control group was 75.8%,with statistical significance(χ2 =14.25,P<0.05). Follow up in 6 ~8 weeks,relapse rate of the observation group was 14.1%,relapse rate of the control group was 37.1%,with statistical significance(χ2 =10.53,P<0.05).Conclusion Suhuangzhike capsules and Desloratadine Citrate Disodium has good curative effect used in chronicity allergic pharyngits ,which can be decreased relapse .

With the development of magnetic resonance (MR) technology, the concern is focused on molecular and physiological imaging besides structural information. Ultra high field MR scanner shows great superiority. 3. 0-T MR scanners provide almost two-fold signal-to-noise ratio (SNR) compared with a standard 1. 5-T MR scanner. The higher baseline SNR can be converted into a variety of alternative benefits. There are still some other changes brought about by 3. 0-T, such as higher sensitivity to motion, susceptibility effect, more difference in resonant frequency among different metabolites, and so on. These features may be a double-edged sword in structural and functional imaging. But with the ceaseless progress of the technology and gains in experience, 3. 0-T systems will provide more information and show more advantages.
Animals ; Humans ; Image Enhancement ; methods ; Magnetic Resonance Imaging ; instrumentation ; methods ; Magnetic Resonance Spectroscopy ; instrumentation ; Sensitivity and Specificity

No abstract available.
Breast* ; Female* ; Fibroadenoma* ; Humans

Objective To investigate the effect of pantoprazole (proton pump inhibitor, PPI) and gefarnate (gastric mucosa protectant) on the prevention of upper gastrointestinal bleeding in patients undergoing post-percutaneous coronary intervention (PCI) dual anti-platelet therapy.Methods This research included 1263 patients taking enteric aspirin and clopidogrel after PCI.The cases were divided into 4 groups: routine treatment group (n=332), PPI group (n=318), gastric mucosa protectant group (n=299), and PPI+gastric mucosa protectant group (n=314).A follow-up for 6 months was observed including gastrointestinal symptoms, upper gastrointestinal bleeding, major adverse cardiac events (MACE), and adverse reactions.Results There were 52 cases of upper gastrointestinal bleeding within 6 months, including 21 cases from routine treatment group, 9 from PPI group, 15 from gastric mucosa protectant group, and 7 from PPI+gastric mucosa protectant group.The incidence of upper gastrointestinal bleeding among the 4 groups within 6 months was statistically different (X2=8.883, P=0.031).The routine treatment group had significant higher rate than the PPI group and the gastric mucosa protectant group (P<0.05), while among other groups there was no significant difference (P>0.05).The upper gastrointestinal bleeding occurred within 3 postoperative months in 34 out of 52 cases (65.4%).There was no statistical significance among the four groups in regard to bleeding occurrence time (X2=4.212,P=0.648).Conclusions Patients undergoing post-PCI dual anti-platelet treatment can reduce the incidence of gastrointestinal bleeding by taking pantoprazole or combined with gefarnate.Intervention against upper gastrointestinal bleeding should start on the first day after PCI and last for a minimum of 3-6 months.

Objective To explore the sleep quality in patients with psoriasis. Methods Twelve psoriatic patients and 19 normal controls were examined by means of polysomnography (PSG). Results Light sleep increased markedly, but medium and deep sleep decreased in psoriatic group. Hypopnea index, apneahypopnea index, lowest oxygen saturation in arterial blood,

Arrhythmogenic Right Ventricular Dysplasia ; Humans

Child ; China ; epidemiology ; Humans ; Tuberculosis ; epidemiology ; prevention & control ; therapy

OBJECTIVE: To review the molecular structure and pharmacological characteristics of DPP-4 inhibitors. METHODS: based on the research literatures in recent years, reviewed the history and development of incretin in diabetes management, especially the R & D process and the molecular structure, pharmacodynamic / pharmacokinetic (PK/PD) and clinical efficacy of DPP-4 inhibitors. RESULTS and CONCLUSION: DPP-4 inhibitors have many advantages and good future in diabetes care.

OBJECTIVE: To establish a highly effective HPLC method for analyzing 1-chlorine-2,4-dinitrobenzene (CDNB), and to determine the activity of GST enzyme in rat liver microsomes (RLM) by use of CDNB as probe and study its enzyme kinetics. METHODS: Welch Materials Ultimate™ XB C18 column (4.6 mm × 250 mm, 5 μm) was used, the mobile phase was acetonitrile-water(7:3), the flow rate was 0.8 mL · min-1, and the detection wavelength was 238 nm. CDNB was incubated with 0.02 mg · mL-1 protein in RLM at 37°C for 7 min and the reaction was terminated by cool acetonitrile. The reaction solution was centrifugated and the supernatant was filtered and analyzed by HPLC. The Vmax, Km and CLint were calculated by Sigma Plot. RESULTS: The retention time of CDNB was about 6 min without any interference. The lowest detection limit of CDNB was 1.0 μmol · L-1, and the calibration curve was linear from 2.5 to 100.0 μmol · L-1. The intra-day and inter-day relative standard deviations were less than 10% respectively. The method recoveries ranged from 99.38% to 108%. The reaction catalyzed by GST was terminated by acetonitrile and the incubation time was 7 min. The kinetic parameters, Vmax, Km, and CLint were 85.45 nmol · min-1 · (mg protein)-1, 15.09 μmol · L-1, and 5.73 mL · min-1 · (mg protein)-1, respectively. CONCLUSION: This method is reliable and the results can ac-curatelly indicate GST enzyme activity, which can be used for the kinetics study of GST in RLM.