1.The nutrition and health status of children should be improved by increasing milk and its product consumption in their diets.
Chinese Journal of Preventive Medicine 2007;41(3):163-164
Animals
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Child
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China
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Dairy Products
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Diet
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Health Promotion
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methods
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Health Status
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Humans
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Nutritional Status
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Nutritive Value
2.PTEN and thyroid tumor
International Journal of Surgery 2010;37(10):687-690
A tumor suppressor gene at 10q23.3, designated PTEN, encoding a dual specificity phosphatase with lipid and protein phosphatase activity, has been shown to play an important role in the pathogenesis of a variety of human cancers and sporadic tumor. In this paper, we reviewed the construction and function of PTEN, and the mechanism of activation in cancer especially in thyroid carcinoma.
3.The influence of Jiuganning decoction on the content of CYP2E1 and cytokine IL-6,TNF in rats models of alcoholic hepatic injury
International Journal of Traditional Chinese Medicine 2011;33(4):305-308
Objective To explore the influences of Jinganning decoction on the content of CYP2E1 and cytokine IL-6,TNF in rats models of alcohdic hepatic injury.Methos 72 male Wistar clean level rats were randomly divided into 6 groups:blank control group,Jiuganning drug toxicity test group,alcoholic hepatic disease model group,Yiganling treatment group,Jiuganning low dose group,and Jiuganning high dose group.Blank control group was treated with physiological saline;Jiuganning drug toxicity test group was treated with Jiuganning decoction to observe toxicity and side effects.Jiuganning low and high dose treatment group were treated with 17.5 g/kg and 23.5 g/kg crude drug.Yiganning treatment group were treated with 0.206 g/kg crude drug.After 4 weeks'treatment,the content of TNF,IL-6,MDA as well as the activity of CYP2E1 and SOD were measured.Results Compared with the alcoholic hepatic disease model group,the content of IL-6(F=46.281,9.101),TNF and the activity (F=62.537)of CYP2E1 of all treatment group were significantly improved(P<0.01).The content of SOD(F=19.210)in the rats serum of all treatment group was significantly increased while the MDA(F=34.952)was decreased.All the indexes in the treatment group had significant differences with the alcoholic hepatic disease and model group(P<0.01).Conclusions The mechanism of Jiuganning decoction can effectively reduce the content of CYP2E1 and IL-6,TNF-a,with the changes of cell physiopathology and the influences of relevant enzymes,reveals the functional routines of the decoction treating hepatic injury:anti-lipid peroxidative,adjusting cytokine's activity,protecting hepatocyte,palliating the hepatocyte inflammation,and easing fibration.
4.The ankle-brachial index of type 2 diabetes
International Journal of Traditional Chinese Medicine 2010;32(5):439,443-
Objective To study the ankle-brachial index of the diabetic gangrene. Methods ABI of the sixty cases with type 2 diabetes were measured. The results were divided into four groups: normal, gently abnormal moderate abnormal severely abnormal group. Results 30 cases were normal, occupying 50% (P>0.05), gently and moderate abnormal attained 5 cases (8.33%) and 4 cases (6.67%) respectively, and the rests 21cases were severely abnormal, occupying 35% (P>0.05).Conclusion The normal ABI was not always indicating type 2 diabetes without the gangrene or tendency.
5.Analysis of the effect of azithromycin combined with the glucocorticoid for the mycoplasma pneumonia in children
Chinese Journal of Primary Medicine and Pharmacy 2013;20(8):1162-1163
Objective To investigate the clinical effects of azithromycin combined with glucocorticoid for the mycoplasma pneumonia in children.Methods 124 children with mycoplasma pneumonia were randomly divided into the study group and the control group with 62 cases in each group.On the basis of the routine symptomatic treatment,the control group was given azithromycin(10mg · kg-1 · d-1) and the study group was treated with azithromycin and hydrocortisone sodium succinate (0.2mg/kg) in the first five days,then stop giving hydrocortisone sodium succinate.The total course was two weeks.Results The study group of children with cough,fever and pulmonary rales disappeared significantly shorter than the control group.Comparison of clinical efficacy,the study group effective rate was 95.2%,the control group was 83.9%,the difference was statistically significant (P < 0.05).Study group had 9 cases of adverse reactions,the control group had 14 cases of adverse reactions,the difference was statistically significant (P < 0.05).Conclusion Glucocorticoid combined with azithromycin is used to treat children with mycoplasma pneumoniae pneumonia,which can improve the therapeutic efficacy and shorten treatment time.It is a better choice of clinical treatment for mycoplasma pneumoniae pneumonia in children.
6.Influencing factors of fixation strength of pedicle screws
Chinese Journal of Tissue Engineering Research 2013;(43):7642-7647
BACKGROUND:Pedicle screw is a good means for internal fixation and has been widely used in clinical practice. OBJECTIVE:To explore the factors influencing the fixation strength of pedicle screws, and to provide biomechanical basis for clinical selection of pedicle screws. METHODS:The recently published studies addressing the biomechanics of pedicle screws were retrieved, and those focusing on the influence of pedicle screw geometry, implantation technique, pedicle anatomical factor, vertebral bone density, screw manufacturing process and material properties on the fixation strength of pedicle screws were retrospectively analyzed, thus providing theoretical basis for clinical treatment. RESULTS AND CONCLUSION:Results showed that, the appearances of pedicle screws such as screw size, screw thread form and fatigue property are the main factors associated with the fixation strength, in addition, vertebral bone density, screw manufacturing process and material properties cannot be ignored. The screw withdrawal force and stability can be improved by increasing screw diameter, improving screw design, strengthening bone density, and modifying operations.
7.Different timing of surgery for joint replacement surgery on femoral neck fracture patients about harris indexes
Chinese Journal of Primary Medicine and Pharmacy 2012;(24):3731-3733
Objective According to the assessment of the curative effect on different operation time of total hiparthroplasty for femoral neck fractures,to explore the effect of the different timing of surgery,itraoperative and postoperative blood loss,early postoperative complications and hip function recovery,and provide theoretical basis for selection of operation time of total hip arthroplasty for femoral neck fractures,to better guide clinical practice.Methods Retrospective analysis 90 femoral neck fracture patients with complete follow-up data for total hip arthroplasty,90 patients were divided into two groups,observation group was given the emergency surgery,the control group was given the delayed operation group.The differences of two groups about operation time,intraoperative blood loss,postoperative drainage,early postoperative complications and postoperative functional restoration of hip joint were compared.Results After 3 months follow-up,the comparison of operation time,intraoperative blood loss and postoperative drainage for the emergency operation group and the delayed operation group,the difference was statistically significant(t=2.37,15.38,22.73,all P<0.05).The emergency operation group and the delayed operation group in the postoperative complications,P>0.05,the difference was not statistically significant.After 1 month,the difference of the two groups of hip joint function by Harris score was statistically significant(t=2.76,P<0.05);and after 3 months,the difference was not statistically significant(P>0.05).Conclusion Emergency surgery can effectively shorten the operation time,reduce blood loss and postoperative drainage and conducive to the recovery of hip function in patients,reduce the pain caused by the disease,but the ultimate the hip function is not affected.
8.The clinical study on metabolic disorders in PCOS women
Chinese Journal of Primary Medicine and Pharmacy 2013;20(7):976-978
Objective To explore the characteristic of metabolic disorders between adolescent and childbearing period PCOS women with obesity or without obesity.Methods 80 PCOS patients were according to obesity divided into 52 patients with PCOS(BMI ≥25kg/m2) and 28 patients with non-obese PCOS (BMI < 25kg/m2),and according to age divided into 36 cases of adolescent(age 14-19 years) and 44 cases of child-bearing age PCOS patients (age 20-32 years).The height,weight,blood pressure,oral glucose tolerance test (OGTT),insulin releasing test (IRT),serum lipid,liver function test were observed.Results (1)Compared with non-obese PCOS women,the obese PCOS women had significantly higher fasting blood insulin,HOMA-IR,fasting blood glucose,AUCG,serum lipid (TC,TG,LDL,ApoB),and the more serious impaired glucose tolerance(IGT).(2)Compared with adolescent PCOS women,the child-bearing period PCOS women had significantly higher AUCG,serum lipid,and more serious IGT.Conclusion The adolescent and child-bearing period PCOS patients always have different degree metabolic disorders.The obese PCOS women especially obese child-bearing period PCOS women may have increased risk of suffering from metabolic disorders in glucose and lipid.For adolescent PCOS women particularly obese ones,we should take early screening,diagnosis,intervention,to avoid the further development and long-term complications.
9.Legislation on the new rural cooperative medical system from the perspective of social insurance
Chinese Journal of Hospital Administration 2013;(2):88-91
Based on an observation of the evolution in rural cooperative medical system,the author proposed the concepts and legal nature of the system.He held that the system is a non-voluntary social insurance,with the country and society as the subjects of liability and oriented to peasants at large.With focused reference of legislation experiences in the USA,Japan and Germany,and summary of local experiments,the author recommended to draft laws and decrees of the system without delay,regulating the conception,goal,legal nature,functionality,regulators,fund raising,and supervision of the system.
10.Risk factors and predictive value of delayed traumatic intracranial hematoma
Chinese Journal of cardiovascular Rehabilitation Medicine 2015;24(2):160-163
Objective:To explore the risk factors its predictive value of delayed traumatic intracranial hematoma (DTICH) . Methods:Clinical data of 95 patients with acute craniocerebral trauma were collected .All patients were divided into DTICH group (n=62) and no recurrent hematoma control group (n=33) .Clinical data were compared between two groups ,Lo‐gistic regression model was used to analyze risk factors .Receiver operator characteristic curve (ROC) was used to assess pre‐dictive value of relative risk factors .Results:Compared with no recurrent hematoma group ,there were significant rise in age [(46.72 ± 6.45) years vs .(52.18 ± 7.13) years] ,hematoma volume [(51.21 ± 11.25)ml vs .(56.89 ± 12.37)ml] , level of fasting blood glucose [(8.13 ± 1.55) mmol/L vs .(10.62 ± 1.73) mmol/L] ,activated partial thromboplastin time [APTT ,(25.27 ± 6.19)s vs .(27.35 ± 7.45)s] and thrombin time [TT ,(17.53 ± 5.14)s vs .(21.26 ± 7.31)s] ,significant increase in percentages of basal cistern compression (24.2% vs .46.8% ) ,brain contusion (42.4% vs .69.4% ) ,bone flap removal (45.5% vs .67.7% ) and positive Babinski sign (39.4% vs .61.3% ) , and significant reductions in GCS score [(9.46 ± 3.29) scores vs .(7.63 ± 3.07) scores] ,systolic blood pressure [(146.57 ± 18.23)mmHg vs .(132.18 ± 17.18) mmHg] and timing of surgery [(12.74 ± 4.39)h vs .(5.47 ± 2.16)h] in DTICH group ,P<0.05 or <0.01;Logistic regres‐sion analysis indicated that coagulation function (APTT ,TT) ,skull fracture and timing of surgery were risk factors for post‐operative delayed hematoma(OR=4.076~5.430 ,P<0.05 or <0.01) ,their area under curve of ROC were 0.826 ,0.748 and 0.661 respectively .Conclusion:Coagulation function ,skull fracture and timing of surgery are risk factors and possess considerable predictive value for postoperative delayed craniocerebral hematoma in patients with craniocerebral trauma .