1.Traumatic cataract and implantation of posterior chamber
Ophthalmology in China 1993;0(01):-
24 cases(25 eyes)of traumatic cataract with various complications were performed combined operations such as vitrectomy and extracapsular lensectomy from behind to leave the anterior capsule followed by imp- lantation of IOL,vitrectomy and removal of intraocular foreign body followed by secon- dary extracapsular extraction of the cataract and IOL implantation when the lens became opaque,and removal of intraocular foreign body with extracapsular extraction of the lens and IOL implantation.The position of incision,the method of anterior capsulotomy and nucleus delivery,the irrigation and aspiration of lens cortex and the timing of the operation were discussed.
2.Analysis of surgical effect of the patients with uveitis-complicated cataract
Recent Advances in Ophthalmology 2001;21(3):197-198
Objective To analyze the surgical results of uveitis-complicated cataract.Methods Cataract phacoemulsification surgery was performed on 31 eyes (29 patients) due to uveitis (iridocyclitis 14 eyes, Fuchs heterochromic cyclitis 7 eyes, intermediate uveitis 7 eyes, Vogt-koyanagi-harada syndrome 2 eyes, and sympathetic ophthalmia 1 eye). Follow-up period was 5~28 months, averaging 15 months. Retrospective analysis was made.Results Postoperative visual acuity≥0.5 was 80%. One eye (Vogt-koyanagi-harada syndrome) showed severe anterior uveitic reaction; One eye (iridocyclitis) had fibrinous membranes on IOL, and white debris on IOL were found in 2 eyes (intermediate uveitis).Conclusion By using less traumatic phacoemulsification technique to ocular tissue, taking meticulous care to avoid stimulating iris, cleaning up cortex thoroughly during surgery and implanting the IOL in the bag, less inflammatory reaction, less complication and better vision acuity postoperatively at relative quiescence period of uveitis can be achieved.
3.Experience of Clinical Pharmacists Participating in the Therapy for an Ovarian Cancer Patient Complicated with Cirrhosis
Wen WU ; Ye YE ; Li CHEN ; Zhen ZENG ; Mei JIN
China Pharmacist 2016;19(5):962-964
Objective:To improve the safety,rationality and efficacy of medication for ovarian cancer patients complicated with cirrhosis by the participation of clinical pharmacists in the therapy. Methods:Clinical pharmacists participated in the therapy for an ovarian cancer patient with cirrhosis,and provided a rational and individualized therapeutic regimen through the drug experience of clinical pharmacists as well as the relevant medical guides and literatures. Results:The therapeutic efficacy was increased by the participation of clinical pharmacists in the therapy,the potential risk of the chemotherapy was avoided and the security of medication was assured. Conclusion:The participation of clinical pharmacists in therapeutic practice can improve the normalization of pharmacotherapy for ovarian cancer patients with cirrhosis,which also can provide ideas and methods for treating the similar patients.
4.Characteristics of mutations of drug tolerance gene rpoB in L-forms Mycobacterium tuberculosis of patients with coal worker's pneumoconiosis and tuberculosis in Huainan mine region.
Jun LU ; Song YE ; Wen-Li SAI
Chinese Journal of Industrial Hygiene and Occupational Diseases 2010;28(1):49-51
Aged
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Anthracosis
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microbiology
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Bacterial Proteins
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genetics
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China
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DNA Mutational Analysis
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DNA, Bacterial
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genetics
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DNA-Directed RNA Polymerases
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Drug Resistance, Bacterial
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genetics
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Humans
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L Forms
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genetics
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Middle Aged
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Mining
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Mutation
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Mycobacterium tuberculosis
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genetics
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isolation & purification
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Tuberculosis
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microbiology
6.Effect of amniotic membrane on the proliferation of YAC-1
Xi SHEN ; Wen YE ; Yisheng ZHONG
Recent Advances in Ophthalmology 2000;20(5):317-318
Objective To investigate the effect of amniotic membrane on the proliferation of YAC-1 in vitro. Methods The YAC-1 cells were cultured with amniotic membrane and their proliferation were observed by MTT automated colorimetry on the lst day, the 3rd day and the 7th day respectively.Results Amniotic membrane could significantly enhance the proliferation of YAC-1 on the lst day, the 3rd day and the 7th day respectively after having been seeded (P<0.01).Conclusion Amniotic membrane can enhance the proliferation of tumor cells (YAC-1), which should be paid attention to during amniotic membrane transplantation for treating ocular surface lesion caused by epibulbar tumors. [Rec Adv Ophthalmol 2000;20(5)∶317-318]
7."Analysis on Bone Mineral Density and Its Relation to ""Kidney-deficiency, Qi-deficiency and Blood Stasis"" among 392 Cases"
Jie YE ; Guodong WANG ; Wen MO
World Science and Technology-Modernization of Traditional Chinese Medicine 2013;(5):1081-1088
This study was aimed to discuss traditional Chinese medicine (TCM) factors of bone mineral density (BMD) in order to figure out the relation of BMD T-Score to the TCM syndrome of kidney-deficiency, qi-deficiency , and blood-stasis . It may provide the scientific basis for TCM treatment of osteoporosis . Patients were collected from August 2010 to April 2011 at the Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine . The assay of BMD was performed with the U . S . HOLOGIC dual-energy radia-tion . The BMD was measured and recorded in the form . All data were collected into the computer using Epi-Data3 . 02 software . Then , the data was analyzed by the SPSS15 . 0 statistical software . The results showed that through the Mann-Whitney U test , the BMD of patients with kidney-deficiency syndrome was worse compared to patients without kidney-deficiency syndrome ( P < 0 . 01 ); the BMD of patients with q i-deficiency syndrome was worse compared to patients without q i-deficiency syndrome ( P < 0 . 01 ); the BMD of patients with blood-stasis syndrome was worse compared to patients without blood-stasis syndrome ( P < 0 . 01 ) . It showed that the BMD of patients with kidney-deficiency , q i-deficiency and blood-stasis was worse compared to patients with-out syndrome of kidney-deficiency , q i-deficiency and blood-stasis . Under a variety of evidence-based BMD distribution , the chi-square test showed that there was significant difference ( P < 0 . 01 ) . It showed that differ-ent BMD had different TCM syndrome distributions . Among normal BMD cases , distributions of syndrome with-out kidney-deficiency, qi-deficiency and blood-stasis occupied the largest proportion. Among osteoporosis cas-es , the distribution of syndrome of kidney-deficiency , q i-deficiency and blood-stasis occupied the largest pro-portion . It was concluded that the syndrome of kidney-deficiency , q i-deficiency and blood-stasis maybe impor-tant factors to influence BMD . It may also be the risk factor of osteoporosis complication . The BMD are relat-ed to the syndrome of kidney-deficiency , q i-deficiency and blood-stasis and their combinations . Among bone mass reduction and osteoporosis cases , the proportion of combination of two or three types of syndromes was more than single one syndrome . It suggested that the combination of kidney-deficiency , q i-deficiency and blood-stasis had more influence on BMD .
8.Functional MRI for patients with visual pathway diseases
Xuzhong SHEN ; Weijun TANG ; Wen YE
Chinese Journal of Ocular Fundus Diseases 2010;26(4):343-348
Objective To observe the results of function MRI and perimetry in patients with visual pathway diseases. Methods Three patients (6 eyes) with pituitary adenoma and craniopharyngioma diagnosed via pathological examination and three healthy volunteers aged from 24 to 30 were collected. The best corrected visual acuity was non-light perception-1. 0 in the 6 sick eyes and 1. 0 in the healthy eyes;all the involved individuals had no other ocular diseases except myopia and without any contraindications of MRI. Common tests including the best visual acuity, fundus test by direct or indirect ophthalmoscope, center static visual field tested by Octopus 101 perimeter, program 32, tendency oriented perimetry were performed. The visual stimulation subtended a field of view of about 12 degrees,consisted of high contrast and drifting checkerboards. MRI parameters: GE signa VH/i 3. 0T scanner. Functional data: GRE-EPI sequence, 20 slices lying perpendicular to the calcarine sulcus. Anatomical data was obtained using 3DSPGR sequence to acquire high resolution. The cortical surface was unfolded and then cut and inflated. Functional data was presented to the inflated surface and subsequently analyzed by AFNI software. Results In six eyes, three had temporal defects, two had upper temporal visual field defects, and the other one did not finish the visual field test. The retinotopic representations of health adults were obtained by using the phase-encoded visual stimulation. The Eccentricity coordinate maps showed that foveal representations lay in the occipital poles and the representations appeared further anterior as eccentricity increased. The polar angle coordinate maps showed that early retinotopically organized areas had a representation of visual field. The visual cortex beneath the calcarine sulcus matched with the upper visual field of the opposite side and which upon the calcarine sulcus matched with the under visual field of the opposite side. Less or no visual cortex response was revealed in the patients' function MRI or the response in injury side was vanished. The visual cortex response related with the visual field defects could not be induced in function MRI. Conclusion There is a good correlation between function MRI data and the results of perimetric evaluation. The function MRI can show the visual cortex response correlated with the visual field defects of the patients with visual pathway diseases.
9.Effect of bFGF on glucose regulated protein 78 expression and apoptosis in human ovarian cancer CAOV3 cells
Liping YE ; Youfeng WEN ; Ying ZHANG
Chinese Journal of Pathophysiology 1989;0(05):-
AIM:To evaluate the effect of bFGF on the apoptosis and the expression of glucose regulated protein 78(GRP78) in ovarian cancer CAOV3 cells.METHODS:Starvation induced cell apoptosis was conducted.After treatment with bFGF,the cell cycle and apoptosis were determined by FACS analysis and Annexin V/PI staining,respectively.The expression of protein kinase B(PKB) and GRP78 were detected by Western blotting and RT-PCR.RESULTS:Compared to starvation group,the cells treated with bFGF were still viable and increased activation of PKB and high expression of GRP78 were observed,which were prevented by PKB inhibitor wortmannin effectively(P
10.Hepatic Hemangioma Accompanied with Peripheral Arterial-Portal Shunt:The Diagnostic Volue of Multi-slice Spiral CT Angiography
Dayong WEN ; Xingyou WU ; Ye YANG
Journal of Practical Radiology 2001;0(06):-
Objective To analyze the multi-slice spiral CT(MSCT) angiographic features of hepatic hemangioma accompanied with peripheral arterial-portal shunt(APS),and to assess the MSCT diagnostic ability and clinical value for peripheral APS.Methods 12 cases of hepatic hemangioma accompanied by peripheral APS underwent triphase enhanced MSCT scan,the images were post-processed with maximum intensity projection(MIP),volume rendering(VR) and then analysed.Results During hepatic arterial phase,the peripheral APS and transient hepatic parenchymal enhancement(THPE) could be visualized on MIP and VR.APS were classified into four types according to the findings on VR and MIP.TypeⅠ: Branch of the portal veins early enhancement in peritumoral wedge-shaped enhanced area,more frequently appeared as parellel track sign;TypeⅡ: Showed early opacification of small portal branchs near tumors,APS more frequently found in peritumoral wedge-shaped enhanced area;Type Ⅲ:Included both typeⅠand typeⅡ signs;Type Ⅳ: Only showed peritumoral THPE.Conclusion MSCT angiography provides a new effective technique for demonstrating and understanding peripheral APS and THPE.