Objective: To examine the association between noise exposure in daily life and depressive symptoms, so as to provide the evidence for reducing the impact of noise in daily life on depressive symptoms. Methods: Based on the 2015 to 2020 database of National Health and Nutrition Examination Survey, demographic information and noise exposure in daily life were collected from people aged 18 years and over. Depressive symptoms were evaluated using the Patient Health Questionnaire-9. The relationship between noise exposure in daily life and depressive symptoms were analyzed using a multivariable logistic regression model. Results: A total of 3 216 individuals were enrolled, including 1 707 males (53.08%) and 1 509 females (46.92%). The mean age was (49.30±18.07) years. There were 491 individuals with noise exposure in daily life, accounting for 15.27%. There were 265 cases with depressive symptoms, accounting for 8.24%. There were 66 individuals exposed to noise in daily life in the group with depression symptoms (24.91%), and 425 individuals exposed to noise in daily life in the normal group (14.40%), with statistically significant difference in noise exposure in daily life between the two groups (P<0.05). Multivariable logistic regression analysis showed that after adjusting for gender, age, educational level, marital status, household income poverty ratio, sleep duration, alcohol consumption and hearing, individuals who had noise exposure in daily life (OR=1.743, 95%CI: 1.258-2.413) were more likely to have high risk of depressive symptoms. Conclusion Noise exposure in daily life was associated with an increased risk of depressive symptoms.