Objective To present the CT and MRI findings of the fibrous dysplasia(FD) of the spine.Methods CT and MRI findings were retrospectively evaluated in 19 cases of FD of spine,all of which were confirmed pathologically.Nineteen patients underwent CT plain scanning(19/19) and 5 had enhanced CT scanning(5/19).Patients were also examined by MRI plain scan(11/11) or MRI enhanced scan (6/11).The location of tumors,the type of bone destruction,the boundary of lesions,internal intensity or signal,the enhancement pattern of lesions,and presence of compression fractures,spinal deformity were observed.Result Nine cases had monostotic FD,while 10 had polyostotic FD.In all the 49 lesions of 19 cases,13 lesions were located in the cervical vertebrae,23 lesions in the thoracic vertebrae,11 lesions in lumbar vertebrae,and 2 lesions in sacral vertebrae.Thirty-three lesions involved both vertebral body and appendix.Pure osteolysis were found in 26 lesions on CT examinations.Peripheral osteosclerosis rims (41/49) and expansive lesions(32/49) were seen.Residual bone crest(28/49) and ground-glass opacity(23/49)were noted.Different degrees of vertebral compression were found in 19 lesions.Five patients had spinal deformity.On T1WI,14 lesions showed intermediate or low signal,and 10 lesions presented as heterogeneous signal.On T2WI,6 lesions had low signal intensity,4 lesions were noted as hyperintensive,and 14 lesions presented as heterogeneous signal.Multiple fluid-fluid levels were found in 1 lesion.Low signal rims were seen in 14 lesions.Twenty lesions of 11 patients had significant enhancement.Conclusion Expansive pattern,ground-glass opacity,peripheral osteosclerosis rims and significant enhancement were helpful findings for the diagnosis of spinal FD.

Human DAB2 interaction protein (DAB2IP) is a novel member of Ras GTPase-activating protein family. It interacts directly with disabled-2 protein (DAB2/DOC2) which suppresses growth of cancers derived from different tissues, including mammary, prostate and ovarian cancers. DAB2IP was identified as an immediate downstream effector mediated by DAB2/DOC2. DAB2IP and DAB2/DOC2 form a unique protein complex that has a negative regulatory effect on the Ras-mediated signal pathway. It is demonstrated that DAB2IP is a tumor suppressor gene inactivated by methylation in several cancers. This article reviews the structure and biological functions of DAB2IP gene as well as its potential roles in carcinogenesis and evolution.

Objective To construct the Chinese cancer-related fatigue assessment tool by using Delphi technique.Methods A certain number of expels were chosen for consulting to form a consuiting scale.Two-round consultations were conducted and the results were analyzed.Results The Chinese cancer-related fatigue assessment scale was formed after 2-round consultation,including 3 dimensions and 20 items,which were:8 items for the physical fatigue,5 items for mental fatigue,7 items for emotional condition.Conclusions The Chinese cancer-related fatigue assessment scale formed by Delphi technique provides a research tool to evaluate fatigue of Chinese cancer patients accurately and presents targeted nursing interventions.

Objective To investigate the value of 3D rapid prototype technology in therapy of complex pilon fractures.Methods In this study,60 patients with pilon fracture who had been hospitalized during January 2013 to May 2014 were randomly and equally divided into a 3D group and a control group according to their hospitalization order.The 3D group:21 males and 9 females,an average age of 34.8 ±6.0 years,13 cases of AO type C2 and 17 ones of AO type C3.The control group:21 males and 9 females,an average age of 35.8 ±6.2 years,12 cases of AO type C2 and 18 ones of AO type C3.The 3D group received surgery aided by rapid prototype and 3D printing while the control group underwent conventional surgery with open reduction and internal fixation.In the 3D group,the distal tibia models were manufactured by 3D rapid prototyping technology based on the 3D reconstructions which were accomplished by computer aided technology.The diagnosis,classification and preoperative plan were then conducted using the models.The 2 groups were compared in terms of operation time,postoperative skin necrosis and infection,and Maryland foot function scoring at the last follow-up.The 2 groups were compatible in preoperative demographic data (P ＞ 0.05).Results There were significant differences between the 3D and control groups in operation time (65.1 ±4.8 minutes versus 80.5 ± 3.6 minutes) and rate of postoperative complications [6.7％ (2/30) versus 16.7％ (5/30)] (P ＜0.05).There was no significant difference between the 2 groups in the excellent to good rate by Maryland foot function scoring at the last follow-up [76.7％ (23/30) versus 73.3％ (22/30)] (P ＞ 0.05).Conclusion Since rapid prototype and 3D printing technology can display the morphology of pilon fracture intuitively and stereoscopically,it helps surgeons with accurate assessment of the fracture.3D printed models of the pilon fracture pre-operatively raise the accuracy of reduction,reduce both operation time and incision complications,and facilitate functional recovery.

Objective To explore the effect of dexmedetomidine(DEX)for blood pressure,heart rate(HR) and SpO2 levels during anesthesia inquiry in elderly hypertensive(HBP)patients.Methods 96 cases with HBP accepted surgery were selected,and were randomly divided into the observation group and the control group,each group in 48 cases,The patients in the observation group continuous pumped into the 4μg/mL of DEX during surgery, while the control group continuous pumped into 0.9% sodium chloride solution during surgery.Heart rate(HR),sys-tolic blood pressure(SBP),diastolic blood pressure(DBP),pulse oxygen saturation(SpO2 )of the two groups after room entrance(T0),after DEX infusion(T1),before intubation(T2),after 2min intubation(T3)and 10 min(T4)after intubation were recorded and compared,extubated time,spontaneous breathing recovery time,call time to eye opening and hospitalization time and the incidence of adverse reactions in two groups were recorded.Results The difference of HR SBP,DBP and SpO2 at T0 and T4 between the two groups was not statistically significant(all P >0.05);HR, SBP and DBP were significantly lower in the observation group than those in the control group at T1,T2,T3(all P <0.05).There were no significant changes of SpO2 in the patientˊs after the room entrance;extubated time,spontaneous breathing recovery time,call time to eye opening and hospitalization time in the observation group were significantly lower than those in the control group(t =8.874,9.073,8.573,all P <0.05).The adverse reactions rate in the observation group was 4.2%,which in the control group was 6.3%,the difference was not statistically significant(P >0.05). Conclusion Continuous pumped DEX has a significant sedative effect in elderly HBP patients during surgery,and does not produce respiratory depression,can help elderly patients with HBP smoothly pass the perioperative period.

Objective To explore the effect of quality control circle activity on improving the quality of nursing document writing. Methods The quality control circle was established and the activity was designed to improve the quality of nursing document writing. The unqualification rate of written nursing documents was compared between pre- and post-activity. Result The unqualification rate of the written nursing documents after the activity was significantly lower than that before activity (P < 0.01). Conclusion The quality of written nursing documents can be improved by developing quality control circle activity.

Objective:To understand the current situation of medical students' professional attitude,find out the exiting problems and put forward some corresponding suggestions.Methods:The medical students' professional attitude was investigated using questionnaire in Shanghai.FResults:Some medical students lacked of professional confidence;the students expected highly towards compensation benefit;the professional satisfaction was low.There existed a correlation between professional values,expect and satisfaction.Conclusions:Perfecting pre-service training is a necessary prerequisite to improve medical students' professional confidence;compensation benefit is one of the referred factors for medical students to choose an occupation;improving medical students' professional view is the foundation of long-term development of medical enterprise;the professional counterpart is the key to ensure medical students' professional satisfaction.

Objective To detect normal rat jejunum epithelial cells to learn about the distribution of peptide YY(PYY)receptor and measured two important parameters of PYY receptor so as to explore the target that PYY binds to and display its physiological function.Methods Receptor radioligand assay was conducted by using 125I-PYY to detect normal rat jejunum epithelial cells.We also measured receptor dissociation constant(Kd),the affinity or the ability that the receptor could bind ligand;maximum binding capacity(Bmax),the concentration of binding site;and Hill coefficient.Results There were PYY receptors in normal rat jejunum epithelial cells.Dissociation constant(Kd)of PYY receptor was(386.69?129.95)pmol/L.Maximum binding capacity(Bmax)was(303.21?116.85)fmol/mg protein.Hill coefficient was 1.PYY receptor had high affinity.Conclusion There are distributions of PYY receptors in normal rat jejunum epithelial cells.Kd means that PYY receptor has high affinity.Bmax means that the number of receptors is limited and decides the characters of saturability.We think that PYY directly inhibits secretion by binding to PYY receptor in jejunum epithelial cells when PYY inhibiting jejunum secretion.

Objective To study the effect of cellulase on the extraction rate of medlar total saccharide, considering three factors of temperature, time and quantity of cellulose. The best extracting condition was determined according to the require of sphere symmetry design. Methods Add cellulase liquid into the medlar slurry and determine the content of medlar total saccharide by DNS method. Result The extraction rate of medlar total saccharide was increased 1.66% by cellulase at temperature of 60 ℃, time of 300 s and cellulase volume of 5 mL. Conclusion Cellulase can promote the extraction rate of medlar total saccharide.

Objective: To explore the effect of health insurance on consumption for rural and urban households. Methods: Using empirical study with the method of quasi-social experiment. Results: Households with health insurance have more consumption than those without health insurance. The higher the coverage of family health insurance improves, the more effects medical insurance would encourage family consumption. Meanwhile, the marginal effect of health insurance on rural households ’ consumption is much bigger than that of urban households. Conclusion: Through enhancing households’ risk tolerance, health insurance reduces households’ precautionary saving motivation and impels to increase the current consumption.