Objective To investigate the clinical value and effect of spinal nerve medial branch ablation through transforaminal endoscopic in treatment of lumbar zygapophysial joint pain. Methods From August 2008 to October 2013 ,96 patients diagnosed as lumbar zygapophysial joint pain were included in the research. 36 patients were treated by spinal nerve medial branch ablation through transforaminal endoscopic ,while 60 patients received conservative treatment. The visual analogue scale (VAS) and Japanese Orthopedics Association(JOA) scores before treatment,1,3,6 and 12 months after treatment were recorded and analyzed. The MacNab scores were recorded and analyzed 12 months after treatment. Results The VAS and JOA scores of surgical treatment group showed significant improvement compared with that before operation (P < 0.05),and there were no significant difference at each time point after surgery. The VAS and JOA scores of conservative treatment group in showed significant improved at 1 months after treatment compared with that before treatment(P<0.05),but there were no significant difference at each time after treatment compared with pretreatment. The VAS and JOA scores of surgical treatment group showed significant improvement compared with conservative treatment group at each time after treatment(P<0.05). The MacNab scores of surgical treatment group(94.44%)was significantly higher than that of conservative treatment group(33.33%). Conclusion The spinal nerve branches ablation under transforaminal endoscopic is an effective and safe minimally invasive spine surgery technique with important clinical value in the treatment of lumbar zygapophysial joint pain.

The changes of leucocyte deformability (LD) and effects of PGMS and PSS on LD in patients with acute cerebral infarction (ACT) were observed. The results showed that leucocyte filtration index (IF) was higher significantly in patients with ACI than that in the normal control ( P

By means of the erythrocyte C3b receptor rosett test and the tumor erythrocyte rosette test, we measured the effects of Sepia on the activity of the erythrocyte C3b receptor and the erythrocyte's immune adhesion to tumor cells in normal persons and in malignant tumor patients. The results showed that Sepia has a markedly active effect on the erythrocyte C3b receptor in normal persons and patients with malignant tumor, and this effect was highest when the concentration of Sepia was 10%. Sepia could markedly enhance the erythrocyte's immune adhesion to tumor cells in normal subjects and in patients with malignant tumor, which was more obvious when the concentration of Sepia was 10%. These results indicate that the anti-tumor action of Sepia is related to activating the erythrocyte immune adhesion function.