1.The Application of Disease Prevention Strategy of TCM on Psychosomatic Recovery of Students Suffering Accidental Damage
Journal of Zhejiang Chinese Medical University 2017;41(6):535-537
[Objective]To propose new strategies on enhancing effectiveness of accidental damage and pioneer new realms for disease prevention strategy, this paper emphasized on analyzing the way and function of disease prevention strategy in therapeutic process of accidental damage.[Method]Literature review was applied to summarize and discuss the effect of some approaches guided by disease prevention strategy, including relieving the emotional tension and none-drug treatment.[Result]Three psychological defense lines were constructed during the therapeutic process which were under the guidance of disease prevention strategy, resulting in contribution to improve cognitive evaluation of patients, improve mood and relieve stress disorder. [Conclusion]Disease prevention strategy plays an important role in the psychosomatic recovery of injured students.
2.Effects of transcranial magnetic stimulation on the learning and memory abilities of those with cerebral infarction
Chuanyu LIU ; Surong ZHOU ; Xuwen SUN ; Zhuli LIU ; Hongliang WU ; Yuanwu MEI
Chinese Journal of Physical Medicine and Rehabilitation 2011;33(1):6-9
Objective To study the effects of transcranial magnetic stimulation (TMS) on learning and memory, and angiogenesis and the dendritic structure of hippocampal CA3 pyramidal neurons after cerebral infarction. Methods Forty-eight male Sprague-Dawley rats were divided into a sham operated group, a model group and a TMS group (n = 16). Rat models of focal cerebral infarction were established with unilateral middle cerebral artery (MCA) suture occlusion in the model and TMS groups. The rats of the TMS group were given 4 weeks of TMS treatment beginning 1 day after the infarction (2 times per day, 30 pulses per time). Their learning and memory abilities were tested with a Y-maze. Angiogenesis and the dendritic structure of their hippocampal CA3 pyramidal neurons were detected after 4 weeks. Results Compared with the model group, learning and memory improved significantly in the TMS group. The average microvessel density of the hippocampus in the TMS group was significantly more than in the model group. The total length of apical dendrites of hippocampal CA3 pyramidal neurons in TMS group was significantly longer than in the model group. Conclusions The improved learning and memory observed following TMS treatment are likely to be related to changes in angiogenesis, the dendritic.structure of the hippocampal CA3 pyramidal neurons, and enhanced synaptic plasticity.
3.Exploration on the assessment system of teaching practice for postgraduate students of pharmacology
Xuwen MAO ; Xiaoqian ZHANG ; Duolikong AERZUYA· ; Wenting ZHOU
Chinese Journal of Medical Education Research 2021;20(9):965-968
Teaching practice is an important link in the process of postgraduate training. This paper analyzes the current situation and existing problems of postgraduate teaching practice, and discusses the influence of new teaching practice mode on postgraduate training. Aiming at the problems existing in the teaching practice of postgraduate students, this paper carries out the reform from five aspects: subject course learning, teaching preparation, theoretical teaching, experimental teaching participation and teaching management participation, and evaluates the implementation effect of the reform. Through the reform of postgraduate teaching practice, the teaching ability and social competitiveness of postgraduate students have been effectively improved. The new teaching practice mode provides new ideas and methods for the cultivation of postgraduate students' teaching ability.
4.Grade of CT in colonic diverticulitis and value in predicting clinical treatment
Wei GUO ; Xuwen ZENG ; Zhiping LIANG ; Song CHEN ; Jie ZHOU ; Yanmei LI ; Mincong HE
Chinese Journal of Medical Imaging Technology 2017;33(11):1670-1673
Objective To investigate th grade of CT in colonic diverticulitis and the value in predicting clinical treatment.Methods CT data of totally 41 patients with colonic diverticulitis were analyzed retrospectively.According to the imaging signs,the grading of diverticulitis cases was performed.Patients with level 1 to 3 were considered as only need non-operative treatment,those with level 4 or 5 were considered as need surgical treatment.The consistency of predictive treatment plans were contrasted with clinical practical treatment results.Results The CT features of colonic diverticulitis were saclike protrusions bulged outside of the bowel wall with colon wall thickening in 40 cases (40/41,97.56%) and fuzzy pericolonal fat space in 39 cases (39/41,97.12%).The diagnostic accuracy of preoperative CT grading in predictive treatment plan was 85.37 % (36/41).Conclusion Colonic diverticulitis have certain characteristic CT findings.CT grading of diverticulitis is helpful to formulate appropriate clinical treatment.
5.Simultaneous Determination of 4 Kinds of Effective Components in Volatile Oil of Forsythia suspensa by QAMS
Ting WU ; Liyuan TAN ; Xuwen WANG ; Kangxin ZHAI ; Jin CHEN ; Xiangping PEI ; Yonggang ZHOU ; Yuhua ZHANG ; Shan WEI ; Shurong ZHANG
China Pharmacy 2019;30(14):1981-1984
OBJECTIVE: To establish a method for simultaneous determination of α-pinene, β-pinene, limonene and α-terpineol in volatile oil of Forsythia suspensa. METHODS: GC method was adopted. The determination was performed on HP-5 capillary column through temperature-programmed route. The inlet temperature was 230 ℃, and detector temperature was 250 ℃; split sampling was applied (split ratio of 8 ∶ 1); the air flow rate was 300 mL/min, the hydrogen flow rate was 30 mL/min, the tail gas flow rate was 30 mL/min, and the injection volume was 1 μL. Using limonene as internal reference, relative correction factors of α-pinene, β-pinene and α-terpineol were established, and the reproducibility of relative correction factors were investigated by using different chromatographs and columns, and chromatographic peak location of components was measured. The contents of above components were calculated with QAMS, and then compared with the results of external standard method. RESULTS: The linear range of α-pinene, β-pinene, limonene and α-terpineol were 16.5-990.0, 38.1-2 287.5, 8.2-491.2, 2.4-142.5 μg/mL, respectively (r≥0.999 1). RSDs of precision, reproducibility and stability tests were all lower than 3% (n=6). Average recoveries were 99.7%-105.5%(RSD<4%,n=9). Compared with limonene (1.00),the average relative correction factors of α-pinene, β-pinene and α-terpineol were 0.91,0.86 and 1.11(n=3); relative retention time were 0.69-0.74, 0.81-0.86, 1.25-1.35(RSD<3%,n=3). By using different chromatographs and columns, RSDs of relative correction factors were 0.21%-4.65%(n=6). Compared with external standard method, determination results of above 4 components were consistent (the absolute value of relative error were all less than 7%). CONCLUSIONS: QAMS can be used for simultaneous determination of 4 kinds of effective components in volatile oil from F. suspensa.