1.Application experience of transumbilical abdominal wall within the three-channel single-incision laparoscopic combined cholecystectomy and appendectomy
Xiongbiao WANG ; Song KE ; Xupeng XIAO ; Xianshi MA
Chinese Journal of Postgraduates of Medicine 2014;37(20):5-7
Objective To explore the clinical valuation and feasibility of transumbilical abdominal wall within the three-channel single-incision laparoscopic combined cholecystectomy and appendectomy.Methods The clinical data of 40 patients who underwent transumbilical abdominal wall within the three-channel single-incision laparoscopic combined cholecystectomy and appendectomy from January 2011 to March 2013 were retrospectively analyzed.Results Forty patients were successfully completed surgery,no transfer laparotomy and death cases,surgery time was 60-80 min,average 70 min,without postoperative incision infection,wound bleeding,bile duct injury,appendix stump fistula and abdominal residual abscess,neither postoperatively used analgesics,1 month after without incision scar,cosmetic effect was remarkable.Half a year's follow-up,the excellent operation evaluation.Conclusions The performer should have accomplish laparoscopic operation skills,and master the indications and the principle.The method of transumbilical abdominal wall within the three-channel single-incision laparoscopic combined cholecystectomy and appedectomy is safe,feasible and valid.The postoperative wound is more minimally invasive and aesthetic effect is obvious.
2.TRIB3‒GSK-3
Shanshan LIU ; Xiaoxi LV ; Xupeng WEI ; Chang LIU ; Qiao LI ; Jiali MIN ; Fang HUA ; Xiaowei ZHANG ; Ke LI ; Pingping LI ; Yang XIAO ; Zhuowei HU ; Bing CUI
Acta Pharmaceutica Sinica B 2021;11(10):3105-3119
Pulmonary fibrosis (PF) is a chronic, progressive, fatal interstitial lung disease with limited available therapeutic strategies. We recently reported that the protein kinase glycogen synthase kinase-3