Objective To study the effect of gamma globulin on serum immune index in neonates with neonatal pneumonia. Methods One hundred neonates with neonatal pneumonia were selected, and they were divided into control group and observation group by random digits table method with 50 cases each. The control group was treated with conventional treatment, and the observation group was treated with conventional treatment combined with gamma globulin. The treatment efficacy, various signs disappearing times, length of stay in hospital and immune indexes were compared between 2 groups.Results The total effective rate in observation group was significantly higher than that in control group:96.00% (48/50) vs. 72.00% (36/50), and there was statistical difference (χ2 = 10.71, P<0.01). The disappearing times of cough, crackles, perioral cyanosis and fever and the length of stay in hospital in observation group were significantly shorter than those in control group:(4.39 ± 1.46) d vs. (6.32 ± 1.61) d, (4.21 ± 0.93) d vs. (5.36 ± 1.08) d, (0.83 ± 0.15) d vs. (1.16 ± 0.22) d, (2.53 ± 1.04) d vs. (4.47 ± 1.13) d and (7.68 ± 0.87) d vs. (10.03 ± 1.18) d, and there were statistical differences (P<0.01). The IgG, IgA, IgM, CD4+and CD4+/CD8+levels after treatment in observation group were significantly higher than those in control group: (10.32 ± 2.86) g/L vs. (6.88 ± 0.83) g/L, (1.14 ± 0.13) g/L vs. (0.91 ± 0.25) g/L, (0.94 ± 0.21) g/L vs. (0.85 ± 0.27) g/L, 0.516 ± 0.068 vs. 0.385 ± 0.063 and 1.89 ± 0.35 vs. 1.57 ± 0.33, but the CD8+was significantly lower than that in control group:0.303 ± 0.046 vs. 0.349 ± 0.048, and there were statistical differences (P<0.05). Conclusions The gamma globulin can not only significantly improve the curative effect in neonates with neonatal pneumonia and promote the recovery of the clinical symptoms, but also improve the efficiency of cell immunity and humoral immunity ability. It is a kind of effective treatment.

Objective To evaluate the effect of phosphocreatine in the treatment of infant with Pneumonia complicated with myocardial injury.Methods Sixty-eight infants with Pneumonia complicated with myocardial injury were randomized into treatment group (n = 36)and control group (n = 32) .The two groups were both treated with combined anti-infection, antiasthmatic and supporting treatments while the treatment group was given additional phosphocreatine.The ECG,recovery of myocardial enzymes, recovery time of major clinical symptoms and syndromes and the period of hospitalization of the two groups were compared.Results Recovery of ECG and myocardial enzymes in the treatment group (94.44％ and 94.44％)were significantly higher than those in the control group(78.13％ and 75.00％ ,respectively) (x2 =3.93 and 5.11 ,respectively,P ＜0.05).Recovery of clinical presentations were more rapid in the treatment group than that in control group (time for cough recovery, [9.5 ± 2.4]d vs.[11.1 ± 2.6]d ;time for rale disappearance, [8.1 ± 1.9]d vs.[10.3 ± 2.4]d) (t =2.63 and t =4.16 respectively ;P ＜0.05 and ＜0.01 respectively).The period of hospitalization was decreased markedly in the treatment group compared with that in the control group([11.5 ±2.2]d vs.[14.3 ±2.8]d) (t = 4.55, P ＜ 0.01) .ConclusionPhosphocreatine has prominent efficacy in the treatment of infantile Pneumonia complicated with myocardial injury.

ObjectiveTo explore the chnical application value of ultrafine electronic endoscopy on the diagnosis of pediatric diseases of upper digestive tract.MethodsSeventy-five cases suspected upper gastrointestinal diseases from January 2009 to June 2010 were selected and were divided by systematic sampling method into observation group(47 cases) which was diagnosed with ultrafine electronic endoscopy and control group(28 cases) which was diagnosed by normal endoscopy.The data of diagnosis and compliance of two groups were observed and compared.ResultsCompliance rate of observation group and control group had significant difference[ 100.0％(47/47) vs.67.9％(19/28),P ＜ 0.01 ].The incidence rates of nausea,salivation and restless of observation group [ 8.5％(4/47 ),6.4％(3/47),8.5％(4/47 ) ]were lower than those of control group [39.3％(11/28),28.6％(8/28),50.0％(14/28)](P＜ 0.01 or ＜ 0.05).Correct diagnosis rate of control group was 84.2％ (16/19),while that of observation group was 95.7％ (45/47),but comparison of diagnosis showed no significant difference(P ＞ 0.05).The incidence rates of diaphragmatic spasm,sore throat and slow heartbeat in successful examination cases of control group[21.1％ (4/19),31.6％ (6/19),21.1％ (4/19) ]significant higher than those of observation group [0,2.1％ ( 1/47),2.1％(1/47) ](P ＜ 0.01 or ＜ 0.05 ).ConclusionUltrafine electronic endoscopy can achieve the same accuracy as normal endoscopy,but compared with normal endoscopy,it can improve the compliance of children during the examination and reduce the incidence of postoperative complications.

Objective to investigate and evaluate the effect of comprehensive nursing methods for children with influenza a H1N1 influenza virus infection.Methods 72 cases of children infected with H1N1 virus from Dongfeng Hospital Affiliated Hubei Medical College during Aug.2010 to Feb 2015 were selected and their clinical data were investigated, given positive nursing and intervention.Results After comprehensive nursing, 72 cases were cured and discharged, the cure rate was 100%, the shortest length of stay in hospital was 3 days, the longest length of stay was 12 days, average 5.78+1.33 days.The Logistic regression analysis showed that the independent risk factors for non H1N1 virus infection include granulocyte count, antibiotic use time, and hospital stay (P<0.05).Conclusions Influenza A H1N1 influenza virus infection risk factors are mainly hospitalization time and use of antibiotics, long duration and and granulocyte count decreased, but the prognosis is good, also need to strengthen the comprehensive nursing intervention, reduce the risk of infection of children.

Objective To explore the influences of comprehensive care nurses on the fatigue during chemotherapy and the prognosis in children with acute lymphoblastic leukemia.Methods The study investigated 80 children with acute lymphoblastic leukemia who were hospitalized from July 201 0 to April 201 5. The participants were divided into intervention group (n =40)and control group (n =40)using odd-even numeration table.All patients received chemotherapy,however,the patients of control group received routine nursing care,and the patients of intervention group received positive nursing care with humanistic concern serviced by nurses.Results After two months chemotherapy:the crucial effective rate was 82.5% for the intervention group and 62.5% for the control group (χ2 =8.1 34,P <0.05);the fatigue level was assessed by cancer-related fatigue scale and the scores of behavior/severity (5.66 ±1 .09 ),emotion (6.02 ±1 .1 1 ), sensory index (6.22 ±1 .44),recognition/mood (3.45 ±1 .20)for the intervention group which were significantly lower than those of the control group (t =9.1 1 3,5.398,4.982,8.1 1 3;P <0.05).The survival time and disease-free survival time were (36.45 ±1 2.38)and (28.45 ±1 1 .73)months for the intervention group,which was significantly longer than that of the control group (t =7.409,5.01 3;P <0.05 ). Conclusions Comprehensive care nurses can effectively reduce the fatigue level and improve the depression and anxiety during chemotherapy and the prognosis in children with acute lymphoblastic leukemia.It also has positive impacts on improving comprehensive chemotherapy efficacy and prolongs patients′survival life.