In order to observe the pial and intracortical vessels in the upper and lower lips of calcarine sulcus, the normal human visual cortex of 15 brains (30 sides) were studied with scanning electron microscope (SEM), staining for alkaline phosphatase activity, continuous arterio-venous perfusion and clearing of thick sections according to Malligan's procedure. The results are: (1) Superficial pial arteries on visual cortex originate from calcarine artery, parieto-occipital artery, and inferior posterior temporal artery. Their branches destribute on the surface of the upper and lower lips of the calcarine sulcus resembling a comb. Two types of arterial anastomoses were found. The pial veins of the upper lip of the calcarine sulcus empty into the medial parieto-occipital vein, while those of the lower lip empty mostly into the medial occipital vein. (2) Intracortical arteries might be divided into five groups, i.e, short cortical artery, middle cortical artery, long cortical artery, subcortical artery and medullary artery. In general, they send out forward and recurrent branches. Veins might also be classified into five groups accordingly. There are four layers of vascular network within the striate cortex. The 3rd layer was clearly divided into sublayer 3a, 3b, 3c. The capillary density of the sublayer 3b is with lower density, which is just situated in Gennari's band. Angioarchitecture in the unstriate cortex is loosely arranged. The vascular density of each layer has been measured. The relationship between the blood supply of visual cortex and its clinical significance has been discussed as well.

[Objective] To evaluate the effect of fast rehabilitation nursing pathway in patients after artificial hip replacement.[Methods] 86 patients underwent artificial hip replacement were randomly divided into the control group and the experimental group with 43 cases in each group.The control group received routine care,while the experimental group was given fast rehabilitation nursing pathway.Anxiety and pain at 48h after operation were evaluated,and hip joint function(Harris score)was evaluated six months after operation.[Results] Compared with the control group,anxiety and pain score at 48h after operation decreased markedly,and Harris score six months after operation increased significantly.[Conclusions] Fast rehabilitation nursing pathway can reduce both the short-term and long-term efficacy of patients after artificial hip replacement.

Objective To screen the peripheral blood circRNA differently expressed in patients with rheumatoid arthritis (RA) and to explore the pathogenetic role of peripheral blood cicRNA in RA by analyzing the data with bioinformatics.Methods The study was performed in 3 RA cases and 3 healthy controls,using circRNA microarrays to screen the circRNA in peripheral blood of patients with RA.The data were normalized and analyzed by R soft package,screening by fold change and P value and searching the differently expressed circRNAs between the two samples by t test.Bioinformatics was performed to analyze the differently expressed circRNAs.Results The results from circRNA microarrays revealed that 36 circRNAs were significantly al-tered in RA patients (P ＜0.05) compared with the control group.Among them,22 were significantly up-regulated,and the other 14 were down-regulated.The GO analysis of the genes involved in the circRNA showed that these genes participated in the progress of biological regulation,cell differentiation,and metabolism.We predicted the target miRNA of all the differently expressed circRNAs,among the results there was a miRNA (hsa-miR-125a-3p) targeted by a circRNA(hsa_circ_0005397) experimentally confirmed by other studies.The relationships among circRNA-miRNA-Gene were predicted by Cytoscape software.Conclusion There are many differently expressed cireRNAs in peripheral blood of patients with RA,and the circRNAs maybe involved in the regulatory mechanisms of Rheumatoid Arthritis.