Objective: To establish the quality standard for Zhike Qutan oral liquid.Methods: A TLC method was used for the qualitative identification of Platycodonis Radix and Glycyrrhizae Radix et Rhizoma;the content of belamcandin in Belamcandae Rhizoma was determined by an HPLC method on a Waters Symmetry C 18 column(150 mm× 4.6 mm , 3.5 μm)with the mobile phase consisting of acetonitrile-water (14∶86), the flow rate was 1.0 ml·min-1 , the column temperature was 35℃ and the detection wavelength was 265 nm.Results: The TLC spots were clear without interference from the negative control.The linear range of belamcandin was 0.115-2.880 μg (r=0.999 9),and the average recovery was 92.44% (RSD=1.83% , n =6).Conclusion: The method is simple and rapid with good reproducibility, which can be used for the quality control of Zhike Qutan oral liquid.

Objective:To explore effects of abdominal cupping along meridians on body weight, waist circumference and glucose and lipid metabolism in patients with central obesity.Methods:Using the convenient sampling method, a total of 76 patients who were treated in Traditional Chinese Medicine Treatment Clinic of Ningbo Hospital of Traditional Chinese Medicine from March to August 2019 were selected as the research objects. According to the simple random number table method, they were divided into the control group and the observation group, with 38 cases in each group. The control group was guided by health education of lifestyle and behavior based on traditional Chinese medicine theory. On this basis, the observation group took Shenque point as the center and performed flash cupping slowly in a clockwise and counterclockwise direction around the navel. Then cupping moving was performed on the abdomen following abdominal spleen meridian, stomach meridian, gallbladder meridian, kidney meridian, ren meridian and belt meridian from bottom to top and from top to bottom. Finally, cups were keptin Daheng acupoint, Fuai acupoint, Tianshu acupoint, Shuidao acupoint, Zhongwan, Guanyuan and belt meridian acupoint. Intervention was performed once a week, with 4 times as a course of treatment, and 3 courses of treatment were carried out for 12 weeks. The weight, body mass index (BMI) , waist circumference, blood glucose and blood lipid levels of patients of two groups after intervention were compared.Results:A total of 30 patients in the observation group and 34 patients in the control group completed the study. After 12 weeks of intervention, the weight, BMI, waist circumference, fasting blood glucose, total cholesterol and low-density lipoprotein (LDL) levels of the observation group were lower than those of the control group, and the differences were statistically significant ( P<0.05) . Conclusions:Abdominal cupping along meridians can effectively improve waist circumference, body weight, BMI and glucose and lipid metabolism in patients with central obesity. The method is simple and safe, which is worthy of further promotion.

Purpose/Significance To solve the problem that regional clinical research data are difficult to integrate efficiently,and to promote"Chinese evidence"and"Chinese protocol"in the global clinical research community.Method/Process Based on the standard-ization theory,the data standardization system is proposed,and the construction and application methods of the regional clinical research data platform are explored with the integration of multi-center clinical research data as the starting point.Result/Conclusion The theo-retical framework of the regional clinical research data platform has been preliminarily established,and the clinical research capabilities of tertiary hospitals in Shanghai have been significantly improved.