1.Analysis of risk factors for acute kidney injury after type Stanford A aortic dissection surgery
Chinese Journal of Thoracic and Cardiovascular Surgery 2012;(10):603-604,613
Objective To determine the risk factors for acute kidney injury following type Stanford A Aortic Dissection surgeryies.Methods It's a restrospective study.The clinical data of 176 patients undergoing type Stanford A Aortic Dissection surgery from Septerary 2009 to December 2011 were retrospectively analyzed.There were 115 males and 61 females with mean ages(43.20 ± 10.14)years old.The patients were divided into two groups according to whether AKI occurred after operation.Univariate and multivariate analyses were used to evaluate possible pre-,intra-,and post-operative parameters associated with AKI according to AKI Network.Results Among all the patients,AKI occurred in 78 (44.32%),21 (11.93%) of whom underwent continuous renal replacement therapy (CRRT).In hospital mortality was 3.41% in all discharges while 6.45% in AKI patients (P < 0.01).Conclusion Multivariate Logistic regression analysis revealed that increased age,pre-operative left ventricular insufficiency,pre-operative renal insufficiency and long extracorpeal circulation (CPB) time > 140 min were risk factors for the development of AKI.AKI is the most common complication of type Stanford A Aortic Dissection surgery,and is the risk factor of mortality after the surgery.It is important to enhance peri-operative protection of the renal function.
2.The relationship between the leptin and the gastric cancer and gastric-related disease
Xiaoping LI ; Cunzhi HAN ; Xueping CUI
Cancer Research and Clinic 2006;0(11):-
Leptin is a kind of energy-modulation hormone expressed by fat tissue. Its receptor has a wide distributing in human body which affects much physiological systems and metabolize access. With the further researches to leptin, its function is not localized fatness and thinness. Leptin is closely associated with the function of gastric mucosa. It attends the pathophysiological course of gastric cancer and gastric -related disease.
3.Design of New Ambulance Aid to Airport Reserve
Xueping HAN ; Dongchen YIN ; Haibo WANG ; Li LENG ; Jie WANG
Chinese Medical Equipment Journal 2003;0(12):-
Objective To develop a new ambulance aid on airport rescue of pilot and solve the difficult problems on medical staff, which carry the wounded from high aircraft cabin to the ground. Methods The device owned QG 0.85 trailer chassis. On the basis of it, self-made manual flexible extension-jib, flexible extension ladders and safety board were designed. The safety board was used to fix wounded pilots to protect secondary injury of backbone and C-spine. Results The maximal speed of equipment was 80km/h and spreading time is 3~7min, operating time is 4min and lifting height is 6 000mm. Conclusion The ambulance aid can be used in the location of flight accident quickly and rescued the pilots rapidly, adapted to any type fighters and met the needs of medical support in flight.
4.Efficacy of laryngeal mask airway proseal and laryngeal mask airway classic in gynecological patients undergoing laparoscopic surgery
Shengkai GONG ; Xueping HAN ; Yan ZHANG ; Yanli MA ; Yanzi CHANG
Chinese Journal of General Practitioners 2012;11(6):454-456
Sixty gynecological patients undergoing laparoscopic surgery during October 2010 to June 2011were randomly divided into 2 groups:laryngeal mask airway proseal ( PLMA group,n =30 ) and laryngeal mask airway classic (CLMA group,n =30).Laryngeal mask was inserted after induction.The heart rate (HR),mean arterial pressure (MAP),airway sealing pressure,the average time of placement,the pulmonary satisfaction and complications were recorded.There was no significant difference in heart rate and MAP between the two groups(P>0.05).The airway sealing pressure [ (26 ±6) cm H2O ( 1cm H2O =0.098 kPa) vs.(16±5) cm H2O],the average time of placement [(36±5) vs.(24±6) s)] and the excellent lung ventilation(90% vs.73% ) in the PLMA group were more significantly increased than those in the CLMA group(P <0.05).PLMA can assure good airway sealing and is more suitable for gynecological patients undergoing laparoscopic surgery.
5.Change trend of clinical characteristics of aortic dissection over 10 years in Henan
Xianrong SONG ; Xueping HAN ; Zhaoyun CHENG ; Xiaohang WANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2014;30(3):164-166
Objective To discuss the clinical epidemiology features and change trend of aortic dissection (AD) in Henan Province.Methods Retrospective analysis of consecutive 906 patients with AD over 10 years in Henan Provincial People' s Hospital,the First Affiliated Hospital of Zhengzhou University and Henan Provincial Chest Hospital.Hospital records and prognosis were compared between two five-year periods.Results 906 cases with AD were hospitalized during the past 10years.The mean age was (50.2 ± 9.8) years.The male/female ratio was 3.49 ∶ 1.Hypertension was present in 60.3 % of all patients.Heavy smoking history was elicited in 32.2% of all patients.Type A dissection were identified in 57.8% of all the cases,and type B in 42.2%.In-hospital mortality of acute type A dissection was 21.8%,acute type B dissection 6.8%.In two five-year periods,the total number of cases increased by 216%,among which type A was the fastest,increased by 294%,Changes of mean age and male/female ratio were not significant.For acute AD,changes of prognosis in one year improved,and reach statistical significance (P < 0.05).Conclusion This study provides insight into current regional profiles of AD.The number of hospitalized patients with AD is increasing dramatically.The mean age of the first-attack is much younger and the male ration is much higher than that reported by other regional researchers.These data support the urgent need for further improvement in prevention and treatment of AD.
6.Challenges facing the knowledge service in aviation medicine and their countermeasures
Yan JIAO ; Fanghu ZHONG ; Yan LIU ; Yange ZHANG ; Li YU ; Xueping HAN
Chinese Journal of Medical Library and Information Science 2016;25(4):49-51
After the current situation of knowledge service in aviation medicine was analyzed, the major problems in restrict security systems, few information access approaches, and difficulties in team construction for the knowledge service in aviation medicine were pointed out, with measures that should be taken in knowledge service put for-ward, such as keeping abreast of the key task in research of aviation medicine, making use of open access re-sources, digitalizing paper-type resources, organizing and revealing the knowledge in resources by making use of information technologies.
7.The effects of different values of PEEP on heart index, stroke volume variation and oxygen transport index in patients monitored by FloTrac/Vigileo system
Zhentao SUN ; Ning WANG ; Xueqing SUN ; Dao XIANG ; Yanan CAO ; Xueping HAN ; Suen REN
Tianjin Medical Journal 2017;45(3):294-296
Objective To investigate the effects of different values of PEEP on cardiac index (CI), stroke volume variation (SVV) and oxygen transport index (DO2I) in patients monitored by FloTrac/Vigileo system, and to provide some references for the hemodynamic management and improvement of oxygenation for patients. Methods Sixty patients scheduled for elective television (TV) auxiliary thoracoscope radical operation for esophageal cancer were included in this study. Data of CI, SVV and DO2I were observed by the FloTrac/Vigileo system. Changes of CI, SVV and DO2I were recorded after anesthesia induction and turn left side (T0), artificial pneumothorax with 0 PEEP after 5 minutes (T1), artificial pneumothorax with 5 PEEP after 5 minutes (T2), artificial pneumothorax with 10 PEEP after 5 minutes (T3), and artificial pneumothorax with 15 PEEP after 5 minutes (T4). Results Compared with T0, CI decreased and SVV increased significantly at T1, T2, T3 and T4(P<0.05). Compared with T1, CI decreased and SVV increased at T4. DO2I increased at T2 and T3 compared with that of T1(P<0.05). Conclusion PEEP may have a certain influence on CI and SVV in the process of operation. The values of 5-10 PEEP can significantly improve oxygenation and have a less influence on hemodynamics, which can be appropriately used in clinical care.
8.Research on Equipment and Technical Requirements for Pilots in Distress Ambulance
Jie WANG ; Wei SUN ; Lili ZHANG ; Xueping HAN ; Fanghu ZHONG ; Li YU
Chinese Medical Equipment Journal 1989;0(04):-
Objective To demonstrate medical aid techniques and ways of rescue helicopter,explore the variety and quantity of equipped medicines and instruments,develop medical aid equipment on board and solve the problems of lacking standard medical aid equipment in the rescue helicopter of our army.Methods The service demand of medical aid equipment in rescue helicopter was demonstrated by means of investigating and material analyzing.The medical aid equipment was developed.Results The technical specifications of technical methods,treatment principles and drugs,the volume of equipment goods and equipment were formed.The medical aid helicopter has features of small size and light weight,and has a fully furnished on fixation and spread of medical equipment.The helicopter of vibration,noise,jolt,low pressure has no effect on job status of the equipment,which performance stability and reached the design requirements.Conclusion The medical aid technique,method and equipment of rescue helicopter are researched to meet the needs of curing the wounded pilots who had to parachute in emergency situation and solve the problem of training demand in the army.
9.Significance of blood serum 25-hydroxyvitamin D3 in patients with type 2 diabetes mellitus
Rui HAN ; Zhao ZHU ; Xueping CHA ; Hua LIU ; Bingchi SU ; Yumei ZHAO ; Weijun LIU
Clinical Medicine of China 2013;29(9):915-918
Objective To investigate the significance of 25 hydroxyvitamin D3 (25 (OH)D3) in patients with type 2 diabetes mellitus by comparing the differences of serum 25-hydroxyvitamin D levels between type 2 diabetes mellitus patients and healthy people.Methods One hundred and forty-seven patients with type 2 diabetes mellitus were selected as the T2DM group,and 135 healthy people were selected as the normal control (NC) group.The level of serum 25 (OH) D3 was detected by ELISA.Clinical data were recorded and biochemical indexes were also detected.Statistical analysis was performed.Results (1) Serum 25 (OH) D3 level in T2DM group was low,but there was no significant difference between two groups((23.10 ± 1.59) μg/L vs.(23.11 ± 1.65) μg/L; t =0.064,P =0.949),as well as between men and women in the 2 populations (T2DM men vs.women(23.22 ± 1.54) μg/L vs.(22.95 ± 1.65) μg/L; t =0.209,P >0.05; NC men vs women(23.03 ± 1.73) μg/L vs.(23.18 ± 1.59) μg/L; t =0.436,P >0.05) ; (2)The prevalence of vitamin D insufficient and deficiency in T2DM group was high,but it was not statistically significant between two groups (98.0% vs.94.8 % and 2.0% vs.5.2% ; x2 =2.034,P =0.154) ; (3) Serum 25 (OH) D3 in T2DM group has a significant negative correlation with triglycerides (r =-0.218,P < 0.01).Conclusion (1) Vitamin D level was low in both the healthy and T2DM populations in the southern region of China,the prevalence of vitamin D insufficient and deficiency was up to 90%.(2)Triglyceride is the only independent risk factor to T2DM population.
10.Intraoperative different setting of respiratory parameters influence the early postoperative cognitive function after gynecological laparoscopic surgery
Zhentao SUN ; Xueqing SUN ; Xueping HAN ; Wei ZHANG ; Yanan CAO ; Yingying DU
The Journal of Clinical Anesthesiology 2014;(7):686-688
Objective To investigate the influence of different respiratory parameter setting during gynecological laparoscopic surgery on early postoperative cognitive function.Methods Eighty patients undergoing elective ovarian cancer or cervical cancer were grouped randomly into groups A, B,C and D.In group A patients were ventilated with respiratory parameters of VT 8 ml/kg,RR 12 times/min.While patients in groups B,C and D with identical minute volume 105 ml/kg though with respective RR of 12,1 5 and 18 times/min respectively.Patients in four groups were all graded by the MMSE at time points of preoperation(T0 ),postoperative 1 h(T1 ),6 h(T2 ),24 h(T3 ),48 h(T4 ), 72 h(T5 ).PaCO2 of arterial blood gas were tested before pneumoperitoneum(Ta)and immediately af-ter pneumoperitoneum(Tb).Results PaCO2 at Tb was higher in each group than that at Ta(P <0.05).Patients in group A showed the highest PaCO2 at Tb while PaCO2 in group C were lowest. The MMSE scores in group C were significantly higher than those in other groups at T1-T3 (P <0.05).The values at T4 in group A were lower (P <0.05)than those in other groups.Values at T1-T4 in group A were lower than that at T0 (P <0.05).In groups B and D at T1-T3 MMSE scores were lower than those at T0 and patients in group C showed lower MMSE scores at T1 and T2 (P <0.05).Conclusion Early postoperative cognitive function can be improved by regulating intraoperative respiratory parameters properly and increasing minute volume adequately in gynecological laparoscopic surgery.