1.Problems of traditional Chinese medicine teaching in general medical university and their reforming strategies
International Journal of Traditional Chinese Medicine 2010;32(3):219-220
Traditional Chinese medicine teaching in general medical university was unsatisfied under the influence of many problems such as indefinite purpose,few class hours but many teaching contents,the different theoretical system between traditional Chinese medicine and western medicine,and theory divorced from practice etc.Therefore,the author suggested several measures that may help increasing teaching quality such as making definite course purpose and stimulating students' learning interest,enhancing training of imagery thinking,carefully electing teaching contents,integrating theory with practice and increasing clinical practice etc.
2.Prevention and treatment of fat liquefaction in gynecological obese patients after abdominal incision
Chinese Journal of Primary Medicine and Pharmacy 2012;(23):3547-3548
Objective To explore the best fat liquefaction prevention measures for gynecological obese patients with abdominal incision.Methods 84 gynecological obese patients with abdominal incision were divided into the observation group(46 cases)and control group(38 cases),according to the negative pressure attract ball placed or not in the subcutaneous fat layer during operation.Patients in both groups were taken abdominal incision physiotherapy.Results The fat liquefaction rate of the observation group was 8.7%,which was lower than that of the control group(26.3%)(x2=4.65,P<0.05).Conclusion It is very important to keep the incision dry,smooth drainage for prevention and treatment of fat liquefaction in gynecological obese patients after abdominal incision.
3.Comparison of animal models of hyperlipidemia
Journal of Integrative Medicine 2004;2(2):132-4
OBJECTIVE: To select the proper experimental animal model for research on prevention and treatment of hyperlipidemia. METHOD: Hyperlipidemia models of mouse, rat, golden hamster, guinea pig, rabbit, pigeon and quail often used in the last ten years were compared. RESULTS: Golden hamster and guinea pig models are similar to human beings in lipid metabolism and have unique superiority in experimental study, while the models of rat, mouse, pigeon and quail have significant difference as compared with human beings. Rabbit is one of the best animal models in studying new drugs for regulating lipid and treating arteriosclerosis. CONCLUSION: Factors such as the required time, indexes, the duration of making models, and the cost and feeding of animals should be considered in selecting animal models according with the experimental requirements.
4.Clinical Observation on 62 Cases of Vetigo due to Vertebrobasilar Insufficient Blood Supply and Hyperactivity of Liver-Yang Treated with Tianzhi Granules
International Journal of Traditional Chinese Medicine 2009;31(6):493-494
Objective To observe the clinical effects of treating Vetigo due to Vertebrobasilar Insufficient blood supply and hyperactivity of liver-Yang with Tianzhi Granules. Methods 118 cases were randomly recruited into a treatment group with 62 cases and a control group with 56 cases. On base of routine treatment, the treatment group was treated with Tianzhi Granules orally; and the control group was treated with Duflomed Hydrochloride orally. One course of treatment was 14 days. Results The total effective rates were 96.77%and 78.57% in treatment group and control group respectively. There was a significant difference between the two groups(P<0.05). The blood flow rat(BFR)of brain was improved in both groups, but the improvement of the BFR in brain was significantly better in the treatment group than the control group (P< 0.05). No adverse reaction was found in the treatment group. Conclusion Tianzhi Granules is effective and safe in treating Vetigo due vertebrobasilar insufficient blood supply.
5.Nutrition support therapy for patients with hepatic encephalopathy
Journal of Clinical Hepatology 2016;32(1):178-181
Hepatic encephalopathy is one of the most common complications of liver failure and has a high incidence in hospitalized patients. Most patients with hepatic encephalopathy have varying degrees of malnutrition.In recent years,more and more clinical trials have confirmed that the nutritional support therapy is beneficial to patients with hepatic encephalopathy,and more attention has been paid to nutritional ther-apy.This paper introduces the pathogenesis of malnutrition in hepatic encephalopathy,and reviews the methods for nutrition evaluation and nutritional therapy in patients with hepatic encephalopathy.
6.Hospital Drug Price Levels
China Pharmacy 1991;0(01):-
1 000 yuan were 68.84%,14.34%,14.35%,2.48%,respectively.In terms of percentages of the categories at the levels above 100 yuan,leading the list were anti-neoplastic drugs,followed in descending order by drugs used for hematological system,anti-neoplastic adjuvants,biological response modifiers,anti-fungal drug and immunosuppressive agents etc.CONCLUSION:Hospital drug price level and percentages at each level tended to be more reasonable after many times policy price reduction.
7.Inhibitory effect of Matrine on IL-1β,TNF-αof macrophages induced by LPS
Chinese Journal of Immunology 2016;32(6):820-824,837
Objective:To investigate the effect of Matrine on inhibiting lipopolysaccharide( lipopolysaccharide ,LPS) -induced macrophages to secrete inflammatory cytokines,including tumor necrosis factor-α( TNF-α) ,leukocyte mediated element 1β( IL-1β) on Toll like receptor 4 ( TLR4 ) , c-jun expression. Methods: Cultured macrophage RAW264. 7 of mouse and divided into four groups, including blank control group,matrine group,LPS group,matrine intervention group. Incubated by the concentration was 100 μg/L LPS DMEM for 1 h,then the LPS was discard. Added free serum DMEM or 125. 25 mg/L matrine DMEM to culture. The cells and culture solution of 5,30,60,120 min after the treatment of the above four groups were collected respectively. Detected of mouse RAW264. 7 macrophage TLR4 and c-jun mRNA expression by PCR. Detected of mouse macrophage RAW264. 7 cells c-jun protein expression by immunocytochemical. Measured secretion in cultured solution of TNF-α and IL-1β by ELISA. Results:Expression TLR4 mRNA,c-jun mRNA and c-jun protein and TNF -α and IL-1β secretion quantity indexes of matrine induced and blank group had no statistical significant differences ( P>0. 05 ) . TLR4 mRNA, c-jun mRNA and c-jun protein expression secretion of and TNF-α and IL-1β LPS group at each time point were significantly higher than that of blank group,and the high level to maintain more than 2 h (P<0. 05);matrine intervention group could effectively inhibit LPS induced macrophage TLR4 mRNA,c-jun mRNA and c-jun protein expression and reduce the secretion of inflammatory cytokines TNF-α and IL-1β. Conclusion: Matrine may inhibit LPS induced macrophage mitogen activated protein kinase signal pathway of TLR4 and c-jun expression so that it can effectively reduce the end inflammatory cytokines TNF-α and IL-1β release,effectively inhibit the inflammatory reaction and reduce the degree of endotoxin inflammatory re-sponse.
8.Classic-a Good Teaching Material Highly Recommended
Microbiology 2008;0(11):-
"Microbiology"(color edition),with Prof.Shen Ping and Prof.Chen Xiangdong of Wuhan Uni-versity as the Chief Editors,is the first 4-color microbiological teaching material in China and has been co-edited by a lot of experts in microbiological field.Besides the introduction of fundamental knowledge,it’s also a book full of creativity and inspiration,furthermore,it combines theory with practice systematically,all of which contribute much to the development of the ability of self-study and creativity for students.A large quantity of delicate illustrations enriches the book extraordinarily.
9.Study on Quality Standard of Shuangbai Tincture
Xiaojun YANG ; Wanzheng WU ; Xuemei WU
China Pharmacy 2001;0(10):-
OBJECTIVE:To establish the quality standard of shuangbai tincture.METHODS:The rhubarb and cortex phellodendri in shuangbai tincture were identified qualitatively by TLC.The content of emodin in this preparation was deter-mined by HPLC.RESULTS:In the TLC of the testing samples,the corresponding positions of standard rhubarb and standard cortex phellodendri respectively showed the same color of speckles.The linear range of emodin was0.1176?g~2.3520?g(r=0.9994)and the average recovery was98.81%(RSD=0.45%).CONCLUSIONS:This method is simple,accurate and repro-ducible,and suitable for the quality control of shuangbai tincture.
10.Percutaneous Microwave Coagulation Therapy Combined with ~(125)I Seeds Implantation for Advanced Lung Cancer
Mingyao KE ; Lingling CHEN ; Xuemei WU
Chinese Journal of Minimally Invasive Surgery 2001;0(05):-
Objective To evaluate the efficacy and feasibility of percutaneous microwave coagulation therapy(PMCT) combined with 125I seeds implantation for the treatment of advanced lung cancer.Methods CT-guided PMCT and implantation of 125I seeds were applied to 22 cases of NSCLC,including 15 cases of squamous carcinoma and 7 cases of adenocarcinoma.The maximum diameter of the lesions ranged from 5-12 cm.The part of focuses situated at thoracic wall or surrounding the large vessels and airways was treated with 125I seed implantation,and the other parts were treated with PMCT. Results In all the patients,PMCT was done in one session with multipoint ablation,and an average of 32.4 particles of 125I seeds were implanted for each of the focuses(712 particles in total).The main postoperative complications included slight hemoptysis(7 cases),pneumothorax(4 cases),fever(17) and lung inflammation(11) after PMCT,chest fluid(6),and dislocation of the particles(2).15 cases achieved PR,5 cases were SD,and 2 cases were PD in 2 months after the operation shown by CT.The effective rate(CR + PR) was 68.2%(15/22).The chest pain was relieved in 15 patients,and improved in 4.22 of the cases were followed up for 4 to 18 months(mean 7 months).No enlargement of the chest lesion was detected during the period. Conclusions For the advanced NSCLC sized ≥ 5 cm in diameter,PMCT combined with 125I seeds implantation is safe,minimally invasive,and effective.