1.Relationship Between Diabetic Angiopathy and blood Lipid.
Chinese Journal of Tissue Engineering Research 2001;5(9):89-90
Objective To study the relationship between diabetic angiopathy and blood lipid, and study the role of blood lipid on diabetic angiophy. Methods The concentrations of TC, TG, lipoproteins apolipoproteins and fasting blood glucose were determined in 50 patients without angiopathy, 56 patients with angiopathy and 53 healthy subjects. Results TC, TG, LDL, Apo - B100 in two group were higher than those in healthy subjects ( P < 0. 05 or 0. 01 ), HLD were lower than those in healthy subjucts( P < 0. 05 or 0. 01 ). TC, TG,LDL, Apo - B100 in patients with angiopathy were higher than those in patients without angiopathy( P < 0. 01 ), HLD were lower than those in patients without angiopathy( P < 0. 01 ). FBS was positivaly correlated with TC, TG, LDL, Apo - B100, and nesgatival corrlated with HLD (r=0.22, 0.32, 0.28, 0.21, -0.26, P <0.05) in two group patients. Conclusion FBS was correlated with blood lipid. Obstruction of blood lipid metabolism was an important faiot of type - 2 diabetes mellitus with angiopathy.
2.Bicycolol tablets in treatment of patients with YMDD mutations of HBV
Junwei WANG ; Xueling BAI ; Bing RUAN
Chinese Journal of Clinical Infectious Diseases 2009;2(4):193-196
Objective To evaluate the clinical efficacy and safety of bicyelol tablets in treatment of hepatitis B patients infected with YMDD mutation of HBV. Methods Sixty-eight chronic hepatitis patients infected with HBV YMDD mutants and 100 patients with non-mutants HBV were enrolled in the study. All patients received bicyclol tablets orally 150 mg/d, t. i. d, for 24 weeks. Clinical symptoms, signs and adverse effects were observed, and the blood routine, liver function tests, serum HBV markers and HBV DNA loads were examined at 12th and 24th week of the study, Results After treatment for 24 weeks, the normalization rates of ALT and AST in mutant group were 79.4% ( 54/68 ) and 70. 6% (48/68) ; 11 ( 16. 2% ) patients were markedly effective and 14 (20. 6% ) were effective. Clearance rates of HBeAg and HBV DNA were 27.9% ( 17/61 ) and 17.6% ( 12/68 ), while the seroconversion rate of HBeAg was 14. 7% (9/61). The differences of the above indexes were not statistically significant between mutant group and non-mutant group. Conclusion Bicyciol can both protect liver functions and inhibit virus replication in patients infected with HBV YMDD mutants.
3.Effects of treatment with milkvetch root and red sage root injections on changes in blood viscosity and renal function in patients with early diabetic nephropathy
Xueling RUAN ; Xiuwei ZHANG ; Dongwen ZHENG
Chinese Journal of Practical Internal Medicine 2001;0(02):-
Objective To investigate the influence of treatment with milkvetch root and red sage root injections on changes in blood viscosity and renal function in patients with early diabetic nephropathy(EDN).Methods 160 patients with EDN were randomly divided into two groups.The control group (n=80) was treated with conventional therapy for diabetes,and the treatment group (n=80) was treated with milkvetch root injection combined with red sage root injection based on conventional therapy for 4 weeks.Results After the above-mentioned therapy the parameters of blood viscosity were significantly decreased(P
4.The effects of lipoprotein(a) level in diabetic nephropathy on urinary albumin excretion rate
Xueling RUAN ; Hongchu LIN ; Henglian WU
Chinese Journal of Practical Internal Medicine 2001;0(05):-
0.05).But in the group EDN and CDN,Lp(a) was significantly higher as compared with the former two groups (P
5.The relationship between lymphocyte phenotype and clinical presentation in patients receiving immunotherapy combined with chemoradiotherapy
Jun JIA ; Liqiong LUO ; Xueling RUAN ; Al ET
Chinese Journal of Immunology 2001;0(07):-
Objective:To observe the relationship between lymphocyte phenotype and clinical presentation in cancer patient receiving immunotherapy combined with chemoradiotherapy.Methods:42 patients were enrolled into the study.Among these patients,22 received stimulated normal peripheral blood lymphocytes(PBLs) as well as chemoradiotherapy,and 20 patients received chemoradiotherapy only as control group.Immunotherapy was administrated biweekly,totally 8 times.Results:22 patients receiving immunotherapy had lymphocyte phenotype change which was also in accordance with symptom improvement,but didn't reach statistical significance.Among 22 patients receiving immunotherapy had 15(68.18%) had lymphocyte phenotype change which was in accordance with symptom improvement,including elevation of CD3 + 3,CD + 4(P
6. Practice of constructing a performance evaluation system of teaching faculty in teaching management of municipal general hospitals
Linyi LUO ; Hui ZENG ; Xiaozhi WANG ; Xuejun CHEN ; Lichen YANG ; Jinhe YE ; Xueling RUAN
Chinese Journal of Medical Education Research 2019;18(12):1264-1267
The construction of teaching faculty is not only a core element to carry out medical education in municipal general hospitals, but also a weak link. Constructing a performance evaluation system of teaching faculty has important significance in promoting teaching reform and innovation, and improving teachers' enthusiasm for teaching as well as their teaching quality in municipal general hospitals. Taking the Affiliated Dongguan People's Hospital of Southern Medical University as an example, this paper focused on the construction of teaching faculty and aimed to provide references for municipal general hospitals to build a performance evaluation system through the promotion of a series of measures such as teaching ability assessment, quantitative assessment of teaching work, teaching quality evaluation, and teaching contribution assessment.