1.Effects of different education methods on compliance and satisfaction of the patients with temporomandibular disorders.
Dongmei KANG ; Xuejuan LIAO ; Yue WANG ; Na FENG
West China Journal of Stomatology 2013;31(1):42-48
OBJECTIVETo compare the effects of video or leaflet in conjunction with traditional patient education (TPE) with traditional patient education alone for the compliance and satisfaction of the patients with temporomandibular disorders (TMD).
METHODSOne hundred and thirty-three patients with TMD who needed intra-articular injection of hyaluronate were included and randomly divided into three groups: Group I accepted video education plus TPE, Group II accepted leaflet education plus TPE, Group III accepted TPE alone. All the participants were recorded by demographic characteristics (sex, age) before treatment, and their compliance, satisfaction and self-exercise were also recorded after one month followed-up.
RESULTSThe baseline parameters (sex, age and diagnosis) of the groups were similar (P > 0.05). Seventeen participants lost in follow-up, including 4.5% in Group I, 11.1% in Group II and 22.7% in Group III. There were significant differences in lost rates among the three groups (P = 0.035). The rates of participants who exactly followed the appointed follow-up were higher in Group I and II than in group III (P = 0.04). And the satisfaction rates were 90.5% in Group I, 92.5% in Group II, 76.5% in Group III. The satisfaction rates of Group I and Group II were significantly higher than that of Group III (P = 0.05). The patients in Group I and Group II were more compliant with the self-exercise than that in Group III (P = 0.007).
CONCLUSIONAdding video or leaflet education to the TPE could increase the patients' compliance, satisfaction and execution of the self-exercise.
Humans ; Hyaluronic Acid ; Personal Satisfaction ; Temporomandibular Joint Disorders
2.Effects of oxidized high density lipoprotein on tissue factor expression in ECV304 cell line
Zibin BU ; Zhisheng JIANG ; Zhenni MA ; Ningzheng DONG ; Zhanzhi ZHAO ; Shundong JI ; Fei SHEN ; Miao JIANG ; Jing WANG ; Liqian XIE ; Xuejuan FENG ; Jingjing CHEN ; Changgeng RUAN
Chinese Journal of Pathophysiology 1986;0(04):-
AIM: To investigate the expression of tissue factor(TF) induced by oxidized high density lipoprotein(oxHDL) in human umbilical vein cell line,ECV304,and the related mechanisms.METHODS: Four main groups were designed: the negative,the positive(ECV304 with histamine),the HDL group and the oxHDL group.Quantitative real-time polymerase chain reaction(RQ-PCR) and Western blotting were used to detect the expression level of TF.The specific inhibitors of MAPKs,SP600125(c-jun terminal NH2 kinase,JNK),SB203580(p38 MAP kinase,p38 MAPK),PD98059(extracellular signal-regulated kinase,ERK1/2) were used to investigate the underlying mechanisms.RESULTS: The TF expression in normal ECV304 cell line was not detected.Histamine administration resulted in a significant expression of TF in ECV304 cell line,with strongest effect after 1 h co-incubation at concentration of 1?10-5 mol/L histamine(about 4.8-fold higher expression of TF compared with that of 1?10-9 mol/L histamine).Expression level of TF was detected after stimulated with oxHDL in dose-and time-dependent manners.The highest expression of TF mRNA was found at 20 mg/L oxHDL and 6 h co-incubation,with 1.8-fold and 5.3-fold increase in TF expression,respectively,compared with that at 10 mg/L oxHDL and 2 h co-incubation.20 mg/L oxHDL also caused an apparent augmentation of TF protein expression,about 1.5-fold higher compared with that stimulated by 40 mg/L oxHDL.HDL co-incubation did not cause a detectable expression of TF protein.The mRNA levels of TF in ECV304 cell line induced by oxHDL were decreased by 95.0%,81.0%,87.0%,respectively(all P