1.The treatment of hepatic cavernous hemangioma by suture ligation around the tumor combined with intra-tumor drug injection:a report of 22 cases
Chinese Journal of General Surgery 2001;0(07):-
ObjectiveTo evaluate the effect of suture ligation around the tumor combined with intra-tumoral drug injection to treat hepatic cavernous hemangioma. MethodsTwenty-two cases of hepatic cavernous (hemangioma) underwent laparatomy and suture ligation around the tumor plus intra-tumoral drug injection under direct vision. ResultsThere was no postoperative mortality or morbidity. 22 patients were followed up for 3 months to 4 years. After this treatment for hepatic cavernous hemangioma, the success rate was 100%, and the significantly success rate was 76.19%. ConclusionsThe combined therapy for hepatic cavernous (hemangioma) is safe, reliable, simple and easy to perform.
2.Tat-NBD peptide inhibits inflammation effects related to NF-kB on AR42J cell
Youming LONG ; Xuejin LIU ; Ken CHEN ; Wenrui XIE ; Hui WANG
Chinese Journal of Emergency Medicine 2009;18(4):401-405
Objective To investigate the effects of Tat-NBD(NEMO-binding domain,NBD)peptide on LPS-stimulated AR42J acinus cells inflammatory response.Method Lipopolysaccharide(LPS)was added to culture media at doses of 10 mg/kg for 24 hours to stimulate the AR42J cells.For pretreatment.cells were incubated with different peptides for 2 hours before LPS stimulation.The expression of TNF-α mRNA WaS conducted using a semi-quantitative RT-PCR method.TNF-α protein in culture medium were detected by enzyme linked immunosorbent assay(ELISA).The expression and translocation of the NF-kB-p65 protein of AR42J was determined by Strept Actividin-Biotin Complex(SABC)method.Results LPS(10 mg/L)resulted in an increase of TNF-αmRNA and TNF-αprotein,whereas significant inhibitory effects were observed when cells were incubated with Tat-NBD(WT)just on dose of 0.1 me/L(P<0.05).The Tat-NBD(WT)peptide decreased inflammatory cytokine expression by a dose-dependent manner and its peak role was on dose of 100 mg/L.Consisting with TNF-α expression decrease,NF-kB-p65 expression signitieantly decreased in Tat-NBD(WT)pretreatment group,especially on the largest dose.NO significant changes in the control peptide group.Conclusions Tat-NBD(WT)peptide can inhibit the inflammation of acinus simulated by LPS.
3.Linguistic analysis of primary progressive aphasia
Xingquan ZHAO ; Ruile FANG ; Jingbo CAO ; Xuejin SUN ; Hongyan CHEN
Chinese Journal of Tissue Engineering Research 2006;10(22):162-164
BACKGROUND: Primary progressive aphasia is a degenerative disease of nervous system clinically characterized by the progressive decrease of speech ability and the relatively reserved memory. OBJECTIVE: To investigate the characteristics of speech dysfunction and the clinical features of primary progressive aphasia we by reported onel patient with primary progressive aphasia. DESIGN: A case analysis. SETTING: Department of Neurology, Beijing Tiantan Hospital affiliated to Capital University of Medical Sciences. PARTICIPANT: One male patient of 56 years old with primary progressive aphasia was selected from the Department of Neurology, Beijing Tiantan Hospital in March 2004, he had got education in senior middle school. The patient had been unable to tell the names of daily living objects at the beginning of 2001. Not only his ability of listening comprehension had gradually declined, but his characters had gradually changed except that his memory had not been affected obviously since 2003. Although he was able in self-care now, he could not normally work. METHODS: ① The spoken fluent types of the patient were evaluated with the standards for the fluency of spoken language in Aphasia battery of Chinese. Western battery aphasia was used to assess the type of aphasia of the patient. Boston diagnostic aphasia examination severity grading standard was applied to grade the severity of aphasia. ② The cognitive psychological tests of visual character-figure matching, denomination for figures and oral reading were used to judge whether the patient had verb-noun dissociation. ③The memory of the patient was assessed with clinical memory scale. MAIN OUTCOME MEASURES: ① spoken fluency, the type and grade of aphasia; ② condition of verb-noun dissociation for the patient; ③ memory of the patient. RESULTS: ① Examination of aphasia: The patient presented the spontaneous talking that named the fluent type, there were wrong meanings in his talks so that he was diagnosed as sensory aphasia. The severity of aphasia was separated into grade 3 levels. ② Cognitive psychological test: The correct rates of verbs and nouns in the test of denomination for figures were 15% and 53% respectively, and there was obvious difference (t=0.231, P < 0.05). ③ Clinical memory scale: The memory quotient was 111,and the clinical memory grade was higher than normal. CONCLUSION: The most outstanding clinical characteristics of patients with primary progressive aphasia is speech dysfunction, and there is verb specific injury.
4.Linear measurement accuracy using cone-beam computed tomography for human skull
Xiaolin SUN ; Xuejin WANG ; Zhiguo CHEN ; Lei JIN
Chinese Journal of Tissue Engineering Research 2014;(20):3252-3256
BACKGROUND:Cone-beam computed tomography has been widely applied in the dentistry due to irreplaceable advantages. Among those advantages, linear measurement is one of the important ones. Further studies are suggest to explore the accuracy and repeatability of linear measurement for the whole skul , as wel as the effect of different resolution and scanning thickness on the linear measurement results.
OBJECTIVE:To evaluate the accuracy of linear measurement using cone-beam computed tomography (Newtom VG) on the human skul , with two different voxel sizes.
METHODS:In this study, 22 anatomic landmarks in four dry human skul s were marked and 11 linear measurements were obtained. These were considered to be the gold standard (real measurement). The skul s were scanned by cone-beam computed tomography (Newtom VG) at two voxel sizes:0.3 mm and 0.15 mm. Linear measurement was performed in axial and coronal planes. SPSS software version 17 was used for data analysis between radiographic measurement and real measurement.
RESULTS AND CONCLUSION:The mean differences of real and radiographic measurements were-0.27 to 0.14 in four different sections, and statistical analysis showed no significant difference between linear measurements and gold standard (P>0.05). There was no significant between two different voxel sizes (P>0.05). Cone-beam computed tomography (Newtom VG) is highly accurate and reproducible in linear measurements in the axial and coronal planes. A cone-beam computed tomography scan with a larger voxel size (0.3 mm) is recommended, resulting in lower radiation dose and faster scan time.
5.Facial reconstruction with combined facial, neck and occipital skin flap transplantation.
Xuejin, TAO ; Sanlan, GUO ; Weimin, CHEN ; Jingzhi, MA
Journal of Huazhong University of Science and Technology (Medical Sciences) 2002;22(1):80-1, 86
To treat large facial defect (more than 6 cm x 4 cm in diameter) or a wound with bone exposure to atmosphere by less-traumatic, easier-healing reconstruction method, a pedicle flap including facial, neck, posterior auricle and occipital skin flap was designed and transferred, one by one, to repair facial defect as well as other flap donor sites, but occipital skin flap was only used to cover posterior auricle area. After 2-3 years follow-up, well-healed skin flaps with good color, elasticity and sensation were observed in all 16 patients. It is concluded that this method is effective and practical.
Carcinoma, Basal Cell/surgery
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Cicatrix/*surgery
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Face
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Neck
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Orbital Neoplasms/*surgery
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Parotid Neoplasms/*surgery
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Reconstructive Surgical Procedures/methods
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Scalp
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*Surgical Flaps
6.Management of mandibular hypoplasia using distraction osteogenesis technique.
Xuejin, TAO ; Min, FAN ; Xiang, LING ; Weimin, CHEN
Journal of Huazhong University of Science and Technology (Medical Sciences) 2004;24(1):92-4
By using distraction osteogenesis technique, 3 cases of mandibular hypoplasia were treated by home-made and German-made jaw distractors: including one patient suffered from bilateral ankylosis of temporo-mandibular joint and 2 patients from deficiency of mandible. The duration of distraction osteogenesis was one month. The bone distractor was removed 3 months after operation. Satisfactory results were obtained in all 3 cases. Distraction osteogenesis can successfully be used in mandibular functional reconstruction and has much more advantages than traditional technique.
Ankylosis/etiology
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Ankylosis/surgery
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Bone Transplantation
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Mandible/*abnormalities
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Mandible/*surgery
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Oral Surgical Procedures
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*Osteogenesis, Distraction
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Temporomandibular Joint
7.Transaction log and its analysis applied to hospital information security
Xiaodan FAN ; Junhua ZHONG ; Xuejin LIN ; Jinxiong CHEN
Chinese Medical Equipment Journal 2017;38(6):77-78,82
Objective To study transaction log and apply its analysis to hospital information security to prevent data loss and treat abnormal data.Methods The application of transaction log was described in log backup and database recovery,and the optration of log analysis was explored in HIS.Sqlplus and Ftp tools in Oracle were used to analyze the transaction log.Results The tracking and analysis of the log files contributed to making clear the incident,finding program bug,getting back lost data.Conclusion Log backup,database recovery and log analysis were of great importance for hospital information security,and log analysis has to be emphasized on in the future.
8.Expression of CD44s in lung cancer and its significance
Xiaomei WANG ; Zhiqiang CHENG ; Ling WANG ; Xuejin SU ; Zhuohuai CHEN
Chinese Journal of Pathophysiology 2000;0(08):-
AIM: To investigate expression of CD44s in lung cancer and it's clinical significance. METHODS: A total of 117 primary lung cancer from patients were examined for CD44s expression by immunohistochemical staining. RESULTS: CD44s mostly expressed in non-small cell lung cancer (NSCLC) but not in small ecll lung cancer (SCLC), and squamous cell carcinoma(SCC) showed much stronger expression of CD44s than adenocarcinoma(ADC)(P
9.Postgraduate medical education systems overseas and their insipirations
Liying XING ; Chen WANG ; Xuejin QI ; Xinyu CHEN ; Shengguo JIN ; Qiurong YU
Chinese Journal of Hospital Administration 2015;31(12):884-887
A brief introduction to the development milestones of postgraduate medical education in the world, highlighting the present details of such systems in the United States, United Kingdom, France, Germany and some Asian countries.It is held that common patterns can be identified despite the gaps found in such systems of these countries.In view of the training management system cornmonalities of thecountries,the authors proposed the development directions of residency training in China to enhance thehands-on capability and competence of clinical doctors in a standardized manner.
10.Analysis of early complications after surgery for portal hypertension
Xuejin CHEN ; Jixiong GUO ; Jiaxin LIU ; Jianguo DING ; Hang PAN ; Peng WANG
Chinese Journal of General Surgery 1997;0(06):-
Objective To investigate the relevant factors for development of early postoperative complications in patients with portal hypertension due to advanced schistosomiasis, and to offer a theoretical basis for preventing the occurrence of postoperative complications. Methods The cases of advanced schistosomiasis with portal (hypertension) operated upon over the past 40 years were retrospectively reviewed. Results In 8 240 cases, the complication rate was 19.66% at one month after operation, and the mortality rate was 15.31%. The main causes of death were MDOS, massive hemorrhage into abdominal cavity, hepatorenal syndrome and (recurrence) of bleeding of upper alimentary tract. Conclusions The relevant factors for development of early complications after operation in patients with portal hypertension is related to the cause of portal hypertension, whether or not there is a history of ascites, the timing of operation and the stage of liver function(Child′s classification).