1.Therapeutic Effect of Drug Partition-Moxibustion For Chronic Diarrhea and Its Immunological Mechanism,
Huangan WU ; Hanping CHEN ; Xuegui HUA
Journal of Traditional Chinese Medicine 1993;0(01):-
In this series, 24 cases of ulcerative colitis and 23 cases of chronic colitis were treated with drug partition -moxibustion with total effective rates of 95. 83% and 95. 55% respectively, markedly excelled that of control group treated with western medicine. Comparison made on the results of the 15 cases of ulcerative colitis before and after treatment showed that drug partition - moxibustion inhibits humoral immunity and strengthens cellular immunity. It is suggested that the mechanism might lie on the adjustment on the abnormal ratio between T - lymphocytes subgroups, hence the self - immune state in the patient can be checked and the mucosal lesion in the intestine corrected.
2.Constructing digitized hospitals with Chinese characteristics
Xiongfei LIU ; Jinxiong CHEN ; Xuegui WU
Chinese Journal of Hospital Administration 1996;0(04):-
A digitized hospital is one with network management as its basic mode, information as the primary driving force of its development, information technology as a prop to enhance its technological strength, information culture as a way to change the ways of peoples education and work and their ideological concepts, and construction of information systems as a new growth point of its advancement. While construction of digitized hospitals is a natural trend of historical development and is presently viable, construction of information systems in domestic hospitals must be based on Chinas realities so as to build digitized hospitals with Chinese characteristics. In light of their hospitals experience in building itself into a digitized hospital, the authors point out that it is necessary to formulate in the first place an overall objective in view of the requirements of digitized hospitals and then proceed step by step according to plan.
3.Master plan of the construction of our hospitals information system and implementation
Jinxiong CHEN ; Xuegui WU ; Xiongfei LIU
Chinese Journal of Hospital Administration 1996;0(05):-
The authors sum up the experience of their hospital in the construction of the information system, pointing out that the key to success in this aspect lies in the clarification of objectives and the formulation of a master plan. Then they give a further account of ways for doing a good job of the master plan and its implementation from the perspectives of the software, hardware, and cultivation of talents.
4.Acupuncture and Irritable Bowel Syndrome: A Population-based Epidemiological and Clinical Study
Huirong LIU ; Jianqun XIE ; Huangan WU ; Xiaolong WANG ; Chen ZHAO ; Xuegui HUA ; Shuang ZHOU ; Xiaopeng MA ; Linying TAN
Journal of Acupuncture and Tuina Science 2010;8(2):70-74
Objective:To explore the prevalence of irritable bowel syndrome (IBS) based on a community population of Shanghai and the treatment of IBS by acupuncture therapy.Methods:A population of 1 685 subjects aged between 18-80 years were randomly selected by clustered sampling from the inhabitants in Changqiao Community of Shanghai to receive a questionnaire,for understanding the symptomatology and prevalence of IBS according to modified Manning and Rome II criteria,and the voluntary IBS patients were treated by acupuncture therapy.Results:The community- based prevalence of IBS was 11.45 % and 5.04% respectively according to modified Manning criteria and Rome II criteria.The ratio of male and female was 0.77:1 in IBS patients and the proportion was 10.62% and 12.19% respectively.But there were no significant difference in prevalence between different age groups (P>0.05) .IBS is more common in subjects aged between 45-65 years (38.86%).Regarding the 62 IBS patients treated by electroacupuncture (EA),the total effective rate in Tianshu (ST 25) group (n=32) was 84.38%,and it was 56.67% in Daheng (SP 15) group (n=30),which showed a significant difference.(P<0.05).Conclusion:IBS is a commonly encountered disorder in Changqiao Community of Shanghai and should be taken into consideration for human welfare,disease prevention and further epidemical investigation.Acupuncture treatment is recommended for treating IBS due to its satisfactory therapeutic effect.
5.Progress in Research on Immunological Effect of Macrophages in Ulcerative Colitis
Dan ZHANG ; Xuegui HUA ; Jie LIU ; Xiaoming FENG ; Chen QIAN ; Kai WEI ; Zhijun WENG ; Huangan WU ; Xiaopeng MA
Chinese Journal of Gastroenterology 2014;(8):500-503
Macrophages( Mφ)play an important role in the regulation of immune reaction. Different kinds of cellular microenvironment influence the phenotypes and function of Mφ and induce different immunological effect. Researches showed that there was a strong correlation between the dysfunction of Mφ and development of ulcerative colitis( UC ). Targeted regulation on immunological activity of Mφ may improve the clinical manifestations and pathological changes in UC. Regulation of the activity and migration of Mφ through changing microenvironment might be one of the potential mechanisms of moxibustion in treating UC. Progress in research on immunological effect of Mφ in UC was summarized in this review article.
6.Effects of 0.2% chloroprocaine combined with ropivacaine on epidural labor analgesia and EC50 of ropivacaine
Xuegui HUANG ; Xiaoxuan WU ; Ran CHEN ; Haijuan ZHU
China Pharmacy 2024;35(14):1732-1736
OBJECTIVE To investigate the effects of 0.2% chloroprocaine combined with ropivacaine on epidural labor analgesia and median effective concentration (EC50) of ropivacaine. METHODS Totally 67 parturients who scheduled for vaginal delivery and required epidural labor analgesia were collected from our hospital from July to October 2023 and randomly divided into RL group (33 cases) and R group (34 cases). The concentration of ropivacaine was determined by modified Dixon sequential method. RL group was given 0.2% Chloroprocaine hydrochloride injection+Ropivacaine hydrochloride injection+0.4 μg/mL Sufentanil citrate injection; R group was given Ropivacaine hydrochloride injection+0.4 μg/mL Sufentanil citrate injection. EC50 of ropivacaine, analgesic effect during delivery, total dosage of analgesic drugs, analgesic satisfaction score, the incidence of adverse reactions, delivery status, and Apgar score of newborns were observed in two groups. RESULTS EC50 of ropivacaine, onset time, remedial analgesia rate, the incidence of perineal distension and breakthrough pain and total dosage of analgesic drugs of RL group were significantly lower than R group, and analgesic satisfaction score was significantly higher than R group (P<0.05). There was no statistical significance in the incidence of adverse reactions such as numbness, weakness, and chills in the lower limbs, or the duration of labor, amount of bleeding, mode of delivery, and Apgar score of newborns between 2 groups (P>0.05). CONCLUSIONS For epidural labor analgesia, 0.2% chloroprocaine combined with ropivacaine can reduce EC50 of ropivacaine, improve analgesia effect and have good safety.
7.Application of Modified Preparation Method of Compound Polyethylene Glycol Electrolyte Powder in Colonoscopy for Patients with Constipation
Bing ZHAO ; Zhijiu WU ; Xuegui TANG ; Pengfei KONG ; Taiyu CHEN ; Shihong LIU
China Pharmacy 2021;32(13):1607-1610
OBJECTIVE:To inves tigate the application effect and safety of modified compound polyethylene glycol electrolyte powder(SF-PEG)in intestinal preparation method for patients with constipation undergoing colonoscopy. METHODS :From Jan. 2020 to Aug. 2020,160 patients with constipation undergoing colonoscopy in anorectal department of the affiliated hospital of North Sichuan Medical College were randomly divided into observation group and control group ,with 80 cases in each group. The patients in the control group took 2 boxes of SF-PEG (mixed into 3 000 mL warm water )orally at 3:00 a.m. on the day of examination,and finished within 2 hours. The patients in the observation group took 1 box of SF-PEG (mixed into 1 500 mL warm water)at 20:00 the night before the examination and 5:00 in the morning of the day of examination ,and drank it within 1 hour;1 bottle of Dimethylsiloxane powder (mixed into 75 mL warm water )was taken orally at 7:00 a.m. on the inspection day. The satisfaction of intestinal preparation ,intestinal bubble score ,operation time of colonoscopy ,detection of polyps ,tolerance rate , acceptance rate of repeating intestinal preparation of patients and incidence of adverse reactions were compared between the two groups. RESULTS :The patients of 2 groups successfully completed bowel preparation and colonoscopy. The intestinal preparation total satisfaction rate ,intestinal bubble satisfaction rate ,polyp detection rate ,tolerance rate and repeating intestinal preparation acceptance rate of patients of observation group were significantly higher than control group (P<0.05),while the incidence of nausea and vomiting and total incidence of adverse reactions were significantly lower than control group (P<0.05),and the operation time of colonoscopy was significantly shorter than control group (P<0.05). CONCLUSIONS :Oral administration of SF-PEG in batches combined with Dimethylsiloxane powder for bowel preparation in patients with constipation before colonoscopy have the advantages of high satisfaction with bowel preparation ,less intestinal bubbles ,short operation time ,high detection rate of polyps,high tolerance rate of patients ,high acceptance rate of repeating intestinal preparation and less adverse reactions. It is a safe and effect method for intestinal preparation.