1.Investigation of the demands of chemometrics guidelines in China’s pharmaceutical industry
ZHAO Yu ; SHAO Xueguang ; YIN Lihui
Drug Standards of China 2024;25(1):005-009
Objective: To understand and grasp the current situation and actual demands of China’s pharmaceutical industry, in order to provide a basis for the establishment of the chemometrics guideline in the Chinese Pharmacopoeia.
Methods: Online questionnaire was adopted to investigate the chemometrics backgrounds and demands of pharmaceutical industry practitioners.
Results: The practitioners of China’s pharmaceutical industry had certain expectations and demands for the chemometrics guideline, but the situation of talent reserves was not that optimistic.
Conclusions: It is extremely urgent to develop the chemometrics guideline, as general chapters of the Chinese Pharmacopoeia, which serve as the legal basis to guide the data quality control, the establishment of analytical methods and the verification of analytical methods in analytical practice, so as to ensure the scientific of multivariate analysis methods and reliability of analytical results, and will be conducive to promoting the improvement of China’s pharmaceutical level.
2.Application of Fourier Transform in Current Separation of Fast Scanning Voltammetry
Zonghai CHEN ; Xiangqin LIN ; Xueguang SHAO ; Zhaoxiang DENG
Chinese Journal of Analytical Chemistry 2001;29(6):625-628
A mathematical model of electro-chemical cell was induced according to its electric model. Based on the mathematical model, Fourier transform (FT) was applied to separate the charging current from Faradaic current in fast scanning voltammetric signal. The proposed method was investigated with both simulated voltammogram and experimental voltammogram. The results indicate that the proposed methods can successfully separate the charging current from Fradaic current, and the result is consistent with theoretical model.