Pharmacy intravenous admixture service was built in accordance with the Australian criteria for intravenous drug admixture and managed in light of the ideas contained in the Accreditation Standards for Hospital released by the US Joint Commission International. Cytoxic drugs, total parenter-al nutrition solutions and intravenous infusions were centrally admixted in the service. Aseptic operation was stressed in the admixture of intravenous drugs while the appropriateness of drug use and the rationality of drug formulations were stressed in the review of doctors' orders. In practice, priority was given to environment and equipment management, qualification and certification of personnel and continuous education, the process was standardized, regulations for standard post operation and the rational use of drugs were formulated, and criteria for assessing doctors' orders were established All this has led to satisfactory results.

BACKGROUND:The rapidly developed transplantation of peripheral blood stem cells have been successfully used to substitute bone marrow transplantation and become the first choice method for transplantation of hemopoietic stem cells.It is relatively difficult to collect peripheral blood stem cells from young age and low body mass infants.OBJECTIVE:To investigate the safety and adverse effects of peripheral blood stem cell collection from young age and low body mass through the use of blood cell separator.METHODS:Two type 1 diabetes mellitus infants,aged younger than 2 years old and with body mass less than 15 kg,were treated using autologous hemopoietic stem cell transplantation.The two infants were adequately comforted to lesion the fear of collection.At 1 week prior to collection,calcium agent was orally taken to reduce the incidences of low calcium.Within 24 hours prior to collection,oily food was forbidden,and on the day of collection,milk was forbidden,to avoid chylemia,which influences blood collection.Prior to collection,200 mL 25 Gy y-ray radiated red blood cells suspension was injected into the tube,which was routinely placed in the subclavian vein,to avoid hypovolaemic syndrome and the effects on hematocrit.Individualized collection parameters were set,During collection,blood circulation volume was 3,4 times of systemic blood circulation to ensure sufficient total circulation volume.During isolation,the ratio of ACD to whole blood was kept between 1:11 and 1:13 to prevent sodium citrate poisoning.RESULTS AND CONCLUSION:Peripheral blood stem cells were successfully collected during first intention in each infant.During collection,stable vital signs but no adverse effects were observed.After collection,mononuclear cells weighted 14.71×108/kg and 18.82×108/kg respectively,and CD34+ cells were about 34.13×108/kg and 32.38×106/kg,respectively in each infant.Therefore,it is feasible to collect peripheral blood stem cells from infants of young age and low body mass under sufficient psychological preparation.

Objective To investigate the effect of pelvic intensive training on gait of stroke patients with hemiplegia. Methods 60 stroke patients with hemiplegia were divided into control group (n=30) and observation group (n=30). Both groups received routine rehabilitation training. The observation group received pelvic intensive training, twice a day, additionally. The average step length, the time of each foot and the 3-minute walking distance were tested before and 8 weeks after treatment with Biodex Gait Trainer 2. Results The average step length and the time of each foot of both sides and the 3 minutes walking distance were significantly better after treatment (P<0.001). And the indexes were significantly better in the observation group than in the control group (P<0.001). Conclusion Pelvic intensive training can improve the gait of stroke patients with hemiplegia.

Objective To observe the influence of psychology intervention and family rehabilitation guides on psychological status and quality of life of patients with spinal cord injury(SCI). Methods 24 SCI patients were divided randomly into treatment(n=12) and control(n=12) groups. The treatment group was given to psychology intervention and family rehabilitation, the psychological status and ADL were evaluated individually by SCL-90 and Barthel index on pre-guide and post-guide of six months.Results The discrepancy got statistic meaning on degree of SCL-90 and Barthel index on pre-guide and post-guide（P<0.05）. Conclusion Effective psychology intervention and family rehabilitation guides could impove psychological status and enhance quality of life of patients.

Objective To evaluate the predictive value of modified early warning score (MEWS) and SMART-COP score on mechanical ventilation in patients with severe influenza A H1N1. Methods Fifty cases diagnosed with severe influenza A H1N1 were retrospectively analyzed. The MEWS and SMART-COP score were calculated. The area under the receiver operating characteristic (ROC) curve (AUC) was evaluated using ROC curve. MEWS, SMART-COP score and AUC were analyzed by Z test. Results The AUCs of MEWS and SMART-COP score for predicting mechanical ventilation were 0. 923 and 0. 889, respectively, which were not significantly different (Z=0. 548, P =0. 584).Conclusion Both of MEWS and SMART-COP score are predictive factors of mechanical ventilation in the patients with severe influenza A H1N1.

Objective To compare the effects of robot-assisted gait training with supported treadmill training (BWSTT) for hemiplegic patients after stroke.Methods A randomized,single-blind,controlled study was performed.Forty-eight hemiplegic patients were divided randomly into a BWSTT group and a robot group with 24 in each Both groups received routine rehabilitation training.The robot group also received robot-assisted gait training,while the BWSTT group received treadmill training in which their body weight was supported.Both groups trained 20-30 minutes daily,5 days a week for 8 weeks in addition to their normal rehabilitation sessions.Their lower extremity functions and walking ability were assessed with the simplified Fugl-Meyer assessment (FMA) and using functional ambulation categories (FACs).Average step length,percentage of loading time on each foot and 3 min walking distance were tested using a Biodex Gait Trainer.All the assessments were administered before and 8 weeks after treatment.Results Both groups showed significant improvements in terms of the FMA,FACs,average step length,loading time on each foot and 3 min walking distance.The robot group,on average,showed significantly better improvements in average step length,percentage of loading time on each foot and 3 min walking distance than the BWSTT group.There was no significant difference in lower extremity function or walking ability in terms of the FMA or FACs.Conclusions Robot-assisted training gives better results than BWSTT in terms of improving average step length,equalizing the loading time on each foot and 3 min walking distance.

Objective To observe the effects of a rehabilitation robot and body weight supported treadmill training (BWSTT) on the walking ability of hemiplegic patients after stroke.Methods Sixty hemiplegic patients were divided randomly into treatment and control groups (n=30 in each).The treatment group received training assisted by a leg rehabilitation robot for 10-20 min once daily,6 days per week for 8 weeks in addition to conventional treatments and BWSTT.The control group was only given conventional treatments and BWSTT once daily for 8 weeks.Their lower extremity functions,balance and walking ability were assessed with a simplified Fugl-Meyer assessment (FMA) and using the Berg balance scale (BBS) and Functional Ambulation Categories (FACs).Results After training,both groups showed significant improvements in terms of FMA,BBS and FAC results.The treatment group showed significantly better improvements in lower extremity function,balance and walking ability compared with the control group.Conclusions The lower-limb rehabilitation robot and BWSTT could together improve balance and walking ability.

Objective To explore the value of an advanced reciprocating gait orthosis (ARGO) combined with comprehensive rehabilitation treatment in rehabliltating complete spinal cord injury (SCI) patients. Methods Twelve patients with complete SCI at the T4~L2 level were fitted with an ARGO. Before and after fitting the ARGO,comprehensive rehabilitative excecises were conducted. After training, ambulation was evaluated, and competence in the activities of daily living was evaluated using the Barthel index and Functional Independence Measure. Results The patients' ambulation improved markedly after fitting the ARGO and training. Barthel index and FIM scres improved significantly. All 12 patients achieved therapeutic or functional ambulation. Conclusion With the aid of an ARGO, patients suffering from complete SCI below the T4 level can achieve functional walking and improve their quality of life.

Objective To investigate the effects of exercising on a cycle ergometer on lower limb motor function and the walking ability of hemiplegic stroke patients.MethodsSixty hemiplegic stroke patients were randomly divided into a treatment group and a control group with 30 in each. Both groups were treated with routine rehabilitation, but the treatment group also undertook cycle ergometer training. The training lasted for 10-20 min/d, 6 d/week for 6 weeks. All patients were assessed with the Fugl-Meyer lower limb assessment ( FMA), functional ambulation category (FAC) classification and the modified Barthel index (MBI) pretreatment and 6 weeks post treatment.ResultsBefore intervention there was no significant difference between the two groups in any of the assessments. Six weeks post treatment, the average FMA, FCA classification and MBI results in the treatment group were significantly better than those pretreatment and better than those in the control group.ConclusionsCycling exercise combined with routine rehabilitation training can distinctly improve the motor function of the lower limbs and the walking ability of hemiplegic stroke patients.

Objective:To explore and test a caregiving experience model by Structural Equation Modeling (SEM)in the family caregivers caring for people with dementia in China. Method:Totally 349 elder patients with dementia and their family caregivers were selected and interviewed,using a battery of measures including demo-graphic data of the dyads,impairement of care recipient,caregiver's appraisal of role strain,role gain,negative and positive well-being outcomes. By using the Kramer's caregiver adaptation model as theoretical framework,a care-giving experience model were hypothesized tested by structural equation modeling (SEM). Result:A five-factor model for the caregiving experience was supported by SEM. The model demonstrated that the severity of dementia significantly influenced the caregiver's appraisal of role strain (β=0. 5 1 ,P<0. 05 ),which predicted indirectly neg-ative well-being outcomes of the caregiver (β=0. 63,P<0. 05). On the other hand the caregiver's appraisal of rolegain which was negatively influenced by the severity of parent's dementia (β=-0. 33,P<0. 05),predicted posi-tive well-being outcomes of the caregiver (β=0. 75 ,P<0. 05 ). Conclusion:It suggests that both positive and nega-tive aspects of caregiving experiences could independently impact on the well-being outcomes of adult-child care-givers,and therefore both aspects should be targeted in supportive interventions for family caregivers in China.