1.Clinical significance of serum cystatin C and urinary TGFβ1 in severe eclampsism
International Journal of Laboratory Medicine 2008;29(8):693-694
Objective To investigate the clinical value of surem eystatin C and urinary transforming growth factorβ1(TGF-β1)in patients with severe eclampsism.Methods Serum cystatin C and urinary transforming growth factorβ1 were examined in 35 severe eclampsism women(experiment group,n=35)and normal late pregnant women(control group,n=35).Results The levels of serum cystatin C and urinary transforming growth factorβ1 were both significantly increased in experiment group than those in control group(both P<0.01).The serum level of cystatin C was positively correlative with urinary TGF-β1 level in experiment group(r=0.581,P<0.05).Conclusion The detection of serum cystatin C and urinary transforming growth factorβ1 is useful to assess renal function lesion in patients with severe eclampsism,which contributes to the diagnosis and treatment of severe eclampsism.
2.Capsular tension ring implantation for congenital subluxated lenses
Yu ZHENG ; Xudong SONG ; Zheng GU
Ophthalmology in China 1994;0(02):-
1.5mm)and received CTR scleral fixation.Visual acuity before and after surgery were examined.IOL tilt and decentration were measured with PentaCam system.Complications were also recorded.Main Outcome Measures Postoperative visual improvement,IOL position and complications.Results At the last postoperative examination,best corrected visual acuities of all eyes were increased(P=0.000).The mean IOL tilt was 4.33?2.96?before and 4.11?2.05?after CTR fixation,the mean decentration was 2.56?0.90mm before and 1.19?0.71mm after.No significant differences were found in IOL tilt before and after CTR fixation(P=0.844),but there were significant differences in IOL decentration(P=0.009).Posterior capsular opacification was found in 8 eyes(20.5%)during the follow-up period,and 2 eyes(5.1%)received Nd:YAG posterior capsulotomy.1 eye received IOL scleral fixation because of capsule rupture during CTR implantation.2 eyes suffered from temporary IOP elevation after surgery.No other severe complications occurred.Conclusions Phacoemulsification with CTR and IOL implantation is effective and safe for congenital subluxated lenses.CTR scleral fixation is a necessary supplement for severely subluxated lenses and progressive cases.
3.The therapeutic effects of isokinetic eccentric exercise in patients with knee osteoarthritis
Xudong GU ; Jianhua LI ; Zhisheng XU
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(06):-
Objective To explore the therapeutic effects of isokinetic eccentric exercise (IEE)in patients with knee osteoarthritis. Methods Forty patients, including 70 knees with osteoarthritis, were measured and trained by use of Cybex-6000 and its isokinetic exercise system 3 times per week for 4 weeks. The peak of moment, single largest work, average power and accelerate energy of moment of isokinetic speed in 60?/s、120?/s and 180?/s were measured before and after exercise. The scores of pain and lower limb function were compared before and after IEE. Results The parameters of extensor and flexor groups were significantly increased after exercise, especially the parameters of knee flexors. The scores of pain and lower limb function were also improved. Conclusion IEE could improve effectively the function of knee extensors and flexors in patients with knee osteoarthritis, and relieve the pain.
4.The application of microburst mode for phacoemulsification
Zheng GU ; Xudong SONG ; Yu ZHENG
Ophthalmology in China 1993;0(03):-
Objective To evaluate the effect on the corneal endothelial cell after phacoemulsification using the microburst mode with high vacuum. Design Prospective,observational case series. Participants 98 age-related cataract patients (120 eyes). Metheds All patients having phacoemulsification with the Alcon Legacy 20000 Everest software were assigned to 1 of 3 groups (the burst mode group,the pulse mode group and the continuous mode group). Main Outcome Measures Actual power,effect phaco time,visual acuity,corneal edema,and corneal endothelial cell loss. Results The mean actual power of the burst group was statistically lower than those of the other two groups,the effect phaco time of the burst group was statistically shorter than those of the other two groups. The corneal edema and the endothelial cell loss of the burst group were less than those of the other two groups. Conclusion The microburst mode with high vacuum increased efficiency of ultrasound power and decreased the loss of endothelial cell. (Ophthalmol CHN,2006,15: 201-205)
6.The effect of electromyographic biofeedback combined with swallowing training on dysphagia after stroke
Yun REN ; Xudong GU ; Yunhai YAO ; Jianming FU ; Hankui YIN
Chinese Journal of Physical Medicine and Rehabilitation 2012;(10):752-754
Objective To observe the effect of electromyographic biofeedback combined with swallowing training on dysphagia after stroke.Methods Ninety-five patients with difficulty in swallowing after stroke were randomly divided into a treatment group (48 eases) and a control group (47 cases).The patients in the treatment group were provided electromyographic biofeedback and swallowing training; the patients in the control group received swallowing training only.The therapeutic effect was assessed with Kubota's drinking water test before treatment and 30d after treatment.Results Swallowing in both groups improved after treatment.The total recovery rate in the treatment group was 87.5%,and in the control group it was 68.0%,a significant difference.Conclusion Electromyographic biofeedback can improve the effectiveness of swallowing training after stroke.
7.The effects of robot-assisted walking training system after total knee replacement patients
Jianhua LI ; Tao WU ; Renxiu BIAN ; Xudong GU
Chinese Journal of Physical Medicine and Rehabilitation 2012;(11):806-809
Objective To investigate the effects of robot-assisted walking training after total knee replacement (TKR).Methods Forty TKR patients at 1 week post-operation were randomized into a control group (n =20) and a treated group (n =20).For 2 weeks the control group accepted routine rehabilitation therapy.The treated group received the same treatment as the control group,but also walking training using a robot-assisted walking training system.The results were evaluated using the Hospital for Special Surgery knee rating scale (HSS),knee proprioception grading,Berg scores,and 6 minute walking distance in both groups.All the analyses were administered before the operation and 2 weeks,l month,3 months and 12 months after the operation.Results The treated group had significantly better HSS scores,Berg scores,and 6 minute walking distances than the control group on average.However,there was no significant difference in average knee proprioception between the two groups.Conclusion Robot-assisted walking training was significantly more effective than conventional rehabilitation alone in improving knee joint function,balance ability and walking after TKR.
8.Training the trunk and pelvis of hemiplegic stroke patients
Yaping MIAO ; Hongzhuan YANG ; Jixu XU ; Xudong GU
Chinese Journal of Physical Medicine and Rehabilitation 2011;33(4):285-287
Objective To observe the effects of reinforced trunk and pelvis control training on the motor function of stroke patients. Methods Sixty-two stroke patients were randomly divided into a therapy group and a control group with 31 cases in each group. All were treated with routine medication and regular rehabilitation training.The patients in the therapy group also received trunk and pelvis control training. The Fugl-Meyer assessment scale (FMA) , Barthel index (BI) and functional ambulation categories (FAGs) were used to assess the motor function of the patients before and after treatment. Results After 2 months of treatment there were significant improvements in FMA, BI, FAC and gait in both groups, but the average walking ability in the therapy group was significantly better than that in the control group. Conclusions Reinforced control training of the trunk and pelvis combined with routine rehabilitation improves motor function in hemiplegic stroke patients significantly better than standard rehabilitation alone.
9.Effects of pulsed electromagnetic fields on mechanical allodynia after acute skeletal muscle contusion in rats
Jing WANG ; Changjie ZHANG ; Xudong GU ; Yunhai YAO
Chinese Journal of Physical Medicine and Rehabilitation 2010;32(1):6-8
Objective To observe the effects of pulsed electromagnetic fields (PEMFs) on behavior and mechanical paw withdrawal thresholds (MPWTs) after acute skeletal muscle contusion (ASMC) in rats, and to in-vestigate the application of PEMFs in rats with ASMC during the early stage. Methods Forty-two Sprague-Dawley rats were randomly divided into a PEMF group (P group) , control group (C group) and blank control group ( BC group). ASMC models were set up in groups P and C, and no intervention was applied in the BC group. A PEMF was administered to animals in the P group immediately after the ASMC was inflicted. The behavior of the rats in each group was then observed. The MPWT of each rat was tested 2 days before and 0, 12, and 18 hours after the ASMC was inflicted). Results In the P and C groups, MPWT of the left hind paw at the 12th and 18th hour after ASMC was significantly lower than the baseline pain threshold 2 days before the ASMC. At 18 hours, the MPWT was signifi-cantly higher than at 12 hours in the P group. MPWT at 12 hours in the P group and at both 12 and 18 hours in the C group were significantly lower than in the BC group. MPWT in the P group at 18 hours was significantly higher than in the C group. Conclusions The behavior of rats treated with PEMF immediately after ASMC was improved, and their pain threshold was still elevated 18 hours later.
10.Effects of pulsed electromagnetic fields on the expression of MyoD after acute skeletal muscle contusion
Jing WANG ; Changjie ZHANG ; Xudong GU ; Yunhai YAO
Chinese Journal of Physical Medicine and Rehabilitation 2009;31(5):292-295
Objective To observe the effects of pulsed electromagnetic fields (PEMFs) on histological changes and myogenic differentiation factor D (MyoD) expression in rats with acute skeletal muscle contusion ( ASMC), and to explore the effects of PEMF therapy on rats with ASMC in its very early stages. Methods Forty-two rats were randomly divided into three groups : a treatment group, a control group and a blank control group. ASMC models were established with all the animals in the treatment and control groups. PEMF treatment was admin-istered to the treatment group immediately after the establishment of the ASMC model. Seven rats in each group were sacrificed at the 12th and 18th h after the models were set up. Their triceps surae muscles were sampled and treated with haematoxylin-eosin staining for study using immunofluorescence techniques and a fluorescence microscope. Re-suits In the control group at the 12th h and 18th h, HE staining showed pale cytoplasm and polymorphism in the cell nuclei ; in the treatment group these effects were significantly lighter, but in both groups it was more serious than in the blank control group. In the treatment and control groups, the fluorescence intensity of MyoD at the 18th h was higher than at the 12th h, and at each time point in both groups it was higher than in the blank control group. At the 18th h, fluorescence in the treatment group was stronger than in the control group. Conclusion MyoD expression in rats with ASMC is upregulated by thel8th h after early PEMF treatment. This might be one of the mechanisms ac-celerating the regeneration of skeletal muscles after trauma.