1.MR imaging of anteromedial and posterolateral bundles of anterior cruciate ligament of knee joint
Xia LIU ; Jin CHENG ; Xubin LI ; Xiangke DU ; Yanping SUN
Chinese Journal of Radiology 2012;46(5):445-448
ObjectiveTo improve the visualization of anteromedial and posterolateral bundles of anterior cruciate ligament (ACL) and investigate the optimal MRI plane for the bundles at a 3.0 T MR scanner.MethodsMR images of 149 knee joints were reviewed retrospectively.Display rates of AMB,PLB and their different parts (the top portion,the middle portion and the low portion) on MR different planes including axial,sagittal and coronal planes were analyzed and their differences were compared with the x2 section method.ResultsThere was no statistical difference in the display rates of two bundles of ACL between axial plane ( 115/149,77.2% ) and coronal plane (103/149,69.1% ) (x2 =2.4606,P >0.0125 ).Statistical differences were found between axial and sagittal plane,coronal plane and sagittal plane (21/149,14.1% ) ( x2 =119.5138,92.8695 respectively,P <0.0125 ).There was a statistical difference for the top portion of ACL between axial plane ( 104/149,69.8% ) and coronal plane,sagittal (0/149,0)and coronal planes ( 7/149,4.7% ) ( x2 =135.081,159.7526 respectively,P < 0.0125 ),between sagittal and coronal planes (x2 =7.1684,P < 0.0125 ).For the middle portion of ACL,there was no statistical difference between axial plane ( 108/149,72.5% ) and coronal plane (94/149,63.1% ) (x2 =3.0120,P > 0.0125 ),while statistical differences were found between axial and sagittal plane,coronal planes and sagittal plane ( 10/149,6.7% ) ( x2 =134.7454,104.2173 respectively,P < 0.0125 ).For the low portion of ACL,there was no statistical difference between axial plane ( 103/149,69.1% ) and coronal plane (101/149,73.8% ) (x2 =0.8065,P >0.0125),while statistical differences were detected between axial and sagittal plane,coronal planes and sagittal plane ( 18/149,12.1% ) ( x2 =100.5300,115.9132,P < 0.0125 ). The different parts of ACL displayed low intensity on different MR planes and normal morphology.ConclusionsACL can be displayed on conventional MR planes at a 3.0 T MR scanner to some extent.Axial and coronal planes might be the optimal MRI planes for ACL and its two bundles.
2.Clinical significance of c-erbB-2 and nm 23 expression in gastric cancer
Suzuan CHEN ; Jing YU ; Senzhi ZHU ; Qiuyuan LI ; Juan ZHANG ; Min ZHONG ; Xubin JIN ; Guanghua GUO
Journal of Chinese Physician 2009;11(2):170-172
Objective To investigate the relationship between the expression of c-erbB-2 and rim23, and their clinical significance in gastric cancer. Methods The expression of c-erbB-2 and nm23 were detected by using immunohistochemical (SP) method in 85 surgi-cally removed specimens from patients with gastric cancer. Results The expression rate of c-erbB-2 and nm23 were 74.1% (63/85),52.9% (45/85). c-erbB-2 was positively correlated with the location, size and depth of invasion of gastric cancer, but not related with the histological types and lymph node metastasis. The expression rate of nm23 in patients without lymph node metastasis (85.7%) and in stage Ⅰ+Ⅱ (72.7%) was higher than that in patients with lymph node metastasis (42.2%) and in stage Ⅲ + Ⅳ (46.0%). The depth of inva-sion and clinical stage between the patients with c-erbB-2 over-expression and nm23 low-expression were positively related(P<0.01 or P<0.01). Conclusion c-erbB-2 promoted growth and invasion of gastric cancer, and nm23 restrained metastasis of gastric cancer. Both c-erbB-2 and nm23 could be served as predictors for biological behavior of gastric cancer.
3.Delayed surgical repair of obsolete acetabular comminuted fractures: a report of 24 cases
Jin KANG ; Xiaowei LIU ; Chengli MA ; Jie GAO ; Xubin ZHANG ; Quanshun ZHANG
Chinese Journal of Trauma 2013;29(10):970-974
Objective To investigate the indications,techniques and effects in surgical treatment of stale acetabular comminuted fractures.Methods A retrospective review was made on 24 cases (24 hips) of obsolete acetabular fractures undergone delayed reconstruction due to the combined injuries in other organs from October 2003 to June 2010.There were 18 males and 6 females,at 22-68 years of age [mean (42.2 ± 10.5) years].Mean time from injury to operation was (4.6 ± 1.3) weeks (range,3-6 weeks).According to Letournel classification,there were 11 simple fractures including six posterior wall fractures,one anterior wall fracture,one posterior column fracture,one anterior wall fracture and two transverse fractures and 13 compound fractures including six posterior column with posterior wall fractures,two transverse with posterior wall fractures,one T-shape fracture,two posterior semitransverse fractures and two both-column fractures.Surgery was performed via ilioinguinal approach in two cases,posterior acetabular approach in 13 and the combined approaches in nine.Results All 24 cases were available to average (15.6 ± 10.5) months of follow-up (range,10-36 months).Quality of reduction based on Matta standard was anatomic in 21 cases,unsatisfactory in two and poor in one.Clinical results evaluated using modified d' Aubigne-Postel score were excellent in 21 cases,good in two and poor in one.There were one femoral head necrosis,11 heterotopic ossification and six sciatic nerve transient palsy after operation.Conclusion Delayed open reduction and internal fixation is effective in treatment of obsolete acetabular comminuted fractures.