1.Giant lymph node hyperlasia and its combined paraneoplastic pemphigus: the clinical, histo-pathology and CT findings
Xiaobin ZHANG ; Gaiping LIU ; Xuanzhong ZHENG
Cancer Research and Clinic 2010;22(12):817-821
Objective To explore the CT findings, the clinicopathological features of giant lymph node hyperlasia and its combined paraneoplastic pemphigus. Methods The clinical features,the imaging and the follow-up data of 19 patients surgically confirmed as giant lymph node hyperlasia were analyzed. Results Clinically, the majority of patients not accompanied with paraneoplastic pemphigus abnormal pulmonary,showed asymptomatic, and only a very small number had lower abdominal discomfort or pain.The patients associated with paraneoplastic pemphigus and abnormal pulmonary manifested the special clinical manifestations, CT finding, pathological characteristics. Histopathologically, the hyaline-vascular type was found in 18 cases and mixed type in 1 case. CT scanning showed that the lesions in 18 patients appeared as larger(2.5-15 cm in diameter), solitary, cylindrical soft-tissue masses with marked enhancement. One case was presented as multiple enlarge lymph node at left neck (1.5-5 cm in diameter). Seventeen of 19 cases were smooth at the edge, and ten cases were uniform in density. The calcification was characterized of an arborizing and (or) flocculent pattern and central location in 7 cases, of which, 1 case circumferential distribution and 5 cases scattered with multiple spots or strip. Shapes were cylindrical and spherical or elliptical. All patients with giant lymph node hyperlasia showed marked enhancement after contrast administration at arterial phase and delay scan. Conclusion CT scanning is an effective method in diagnosis, guiding surgery and evaluating prognosis of giant lymph node hyperlasia, especially dynamic contrast-enhanced and delayed CT scanning. It is the critical way for patients complicated with paraneoplastic pemphigus and abnormal pulmonary cases, to diagnose early and resect tumor-like lesions in vivo.
2.Evaluation of MRI in discriminating benign and malignant compression fracture of vertebrae
Hongzhi YANG ; Xuanzhong ZHENG ; Hongxing JIN
Cancer Research and Clinic 2009;21(11):787-788
Benign and malignant compression fracture of vertebrae are common diseases in clinic. Because their therapies are different,it is important to identify them. At present, MRI is the main means in discriminating benign and malignant compression fracture of vertebrae. Sometimes the change of MRI signal in them is overlap, therefore, it is difficult to diagnose accurately. In the recent years, with the appearance of MRI new technology, people have already applied it to work out the difficulty.
3.Imaging diagnosis methods and progress for lymph node metastasis in esophageal carcinoma
Xiufang WANG ; Xuanzhong ZHENG ; Hongxing JIN
Cancer Research and Clinic 2009;21(5):356-358
The article focuses on diagnostic criteria and diagnostic accuracy of the various imaging methods by lymph node metastasis in esophageal carcinoma at present, and compares accuracy of the various imaging methods. In general, the diagnostic accuracy of CT is lower, the diagnostic accuracy of uhrasmall superparamagnetic iron oxide-enhanced MR imaging is higher. Each imaging method has the lower accuracy for the diagnosis of smaller lymph node metastasis. Diagnostic accuracy of endoscopic ultrasonography is higher in the diagnosis of mediastinal lymph node metastasis. Sensitivity of PET/CT is higher for the diagnosis of distant lymph node metastasis.
4.MRI Classification and Manifestations of Discoid Meniscus
Jie ZHOU ; Xiaoguang CHENG ; Xuanzhong ZHENG
Chinese Journal of Medical Imaging 2009;(6):435-438
Purpoes: To discuss the MRI manifestation and classification of discoid lateral meniscus and improve the accuracy of MRI diagnosis for discoid meniscus.Materials and Methods: 70 cases of discoid meniscus verified by arthroscopy were divided into impuberal group(n=30) and adult group (n =40).Following three quantitative parameters were measured.The meniscal width and tibial plateau width on the coronal slice showing the inttercondyloid spine( a),the number of the spine showing butterfly change when the layer thickness was 4mm(b) and the maximum width showing butterfly change on the sagittal slice(c).The discoid meniscus were classified as slab type (n=33),wedge type(n = 19),hypertrophied - horn type(n= 18) according to their shape.Results:69 cases had torn in different extent,a>or =20% (P<0.01) in all of cases.No significant difference in the incidence of each type existed between two groups(P>0.05).Significant difference in the incidence of each type existed in c(P<0.05).Conclusions: a >or = 20% is the most reliable criterion to diagnose discoid meniscus.Using b as the criterion of discoid meniscus is easy to occur missed diagnosis,c in the wedge type is bigger than the one in the hypertrophied type.Age can impact the classification of discoid meniscus.
5.Value of high resolution MRI with DWI in the preoperative diagnosis of rectal cancer
Rui ZHANG ; Hongxing JIN ; Xiaotang YANG ; Xiaosong DU ; Xuanzhong ZHENG
Cancer Research and Clinic 2011;23(7):443-446
Objective To evaluate the value of high resolution MR imaging (MRI) with diffusion weighted imaging (DWI) in the preoperative diagnosis of rectal cancer. Methods 55 patients with rectal cancer may underwent high resolution MRI examinations before surgical operation, and with DWI (b=600, 1000 s/mm2). The apparent diffusion coefficient (ADC) of the tumors were measured. The image findings were compared with pathology. Select 15 patients without rectal lesion, ADC value of the tumors and normal rectal wall were measured. Results High resolution MRI diagnosis rectal cancer sensitivity, specific degree and coincidence rate were 95.7% (45/47), 50.0% (4/8), 89.1% (49/55), high resolution MRI with DWI diagnosis colorectal cancer sensitivity, specific degree and coincidence rate were 100.0 % (47/47), 75.0 % (6/8), 96.4 % (53/55). The high resolution MRI tumor T-staging agreed with the histological stage that was 88.9% (40/45), the diagnosis of T2 stage was 87.5 % (14/16), the diagnosis of T3 stage was 89.6 % (26/29). The same b-valued under the ADC values of rectal cancer tumors and the normal rectal were different (P <0.05). No correlation can be pointed out between ADC and pathological classification of each tumor.Conclusion High resolution MRI with DWI for the rectal cancer preoperative diagnosis and T-staging has higher diagnostic accuracy, DWI can serve as an important supplement sequence of colorectal cancer diagnosis.