[Objective]To summarize Doctor Xuan Guiqi's experience in the treatment of childhood asthma and the idea of improving the curative efficacy. [Methods]By learning from Doctor Xuan and clearing up medical cases, the author finishes the summary on doctor Xuan's clinical experience on child-hood asthma based on the syndrome differentiation and clinical medication.[Results]The childhood asthma is divided into acute and chronic, the former is divided into cold asthma, heat asthma and wind-phlegm types. At the same time, we strengthen pertinence treatment of clearing heat and removing toxi-city, Qi spasmolytics, dispel ing wind and desensitization, activating blood and eliminating stasis, promoting Qi and regulating middle-jiao and relieving dyspepsia.[Conclusions] Doctor Xuan Guiqi's experience in the diagnosis and treatment of childhood asthma can significantly improve the clinical efficacy , and it is meaningful to clinic.

The concept of nutraceutical food was introduced firstly in United State in 1989 by Stephen Defelice, the founder of the Foundation for Innovation in Medicine. It is defined as a product that considered as a food or a part of food, provided medical or health benefits, including disease prevention and treatment”. The health sector should review and re-evaluate the importance and potential of the nutraceutical food market and plan the development strategy for this novel avenue. The unique definition of nutraceutical product is needed. The Ministry of Health should direct the management of these products as medications rather than foods and the regulations of registration, labeling and take testing samples should be available
Food ; Dietary Supplements ; Comment [Publication Type

Allergic reaction to drugs (ARTDs) occurs frequently in adults who are usually suffered from many diseases and who require multiple courses of medications. Investigative result showed that: The incidence of ARTDs in elderly is 6.74%, this incidence in patients of Asthma group is 14.7%. The main cutaneous manifestations of ARTDs in elderly patients included: urticaria and erythematous rashes (42.5%), erythrodermie (14.9%), erythematic multiform (21.3%), fixed drug eruptions (12.7%), vesiculobullous eruptions (6.4%).
Drug Hypersensitivity ; aged

BACKGROUND:Several studies have suggested that hyperbaric oxygen could better protect cranial nerve and brain cels. Hyperbaric oxygen therapy can make oxygen partial pressure rapidly diffusing toward relatively hypoxic brain tissue, so as to increase blood oxygen content in the brain tissue, reduce brain edema and promote the recovery of brain function. OBJECTIVE: To observe the effects of hyperbaric oxygen therapy on brain tissue sweling in rats after middle cerebral artery occlusion, and discuss the possible mechanism of action underlying the neuroprotective effects of hyperbaric oxygen therapy in rats with cerebral infraction. METHODS:Sixty adult female rat models of cerebral infarction were successfuly established by middle cerebral artery occlusion using suture method and then randomly divided into the sham, cerebral infarction and hyperbaric oxygen therapy groups (n=20 rats/group). At 3 days after middle cerebral artery occlusion, apoptosis of nerve cels in the infract area of rats in each group was detected by TUNEL method. At 72 hours after middle cerebral artery occlusion, the gene transcription and protein expression of aquaporin 4/9 and matrix metaloproteinases 9/2 in the peri-infarct area were detected by RT-PCR and western blot analysis. The pathomorphological change in the infract area was observed by hematoxylin-eosin staining. The expression level of glial fibrilary acidic protein was detected by immunohistochemistry. At 24 hours and 3 days after hyperbaric oxygen therapy and at 1 and 2 weeks after middle cerebral artery occlusion, neurological behaviors were evaluated using Longa behavioral scores. RESULTS AND CONCLUSION:After 1, 2 days of hyperbaric oxygen therapy, Longa behavioral scores in the hyperbaric oxygen therapy group were significantly lower than those in the cerebral infarction group (P < 0.05). At 3 days after middle cerebral artery occlusion, cel apoptosis index in the hyperbaric oxygen therapy group was significantly lower than that in the cerebral infarction group (P < 0.05). At 72 hours after middle cerebral artery occlusion, the aquaporin 4/9, matrix metaloproteinases 9/2 gene and protein expression in the hyperbaric oxygen group were significantly lower than those in the cerebral infarction group (P < 0.05). These results suggest that hyperbaric oxygen therapy can play its protective role by decreasing apoptosis of nerve cels in the infarct area and lessening the edema of brain tissue in rats with cerebral infarction.

Based on the analysis of Language Learning Strategies of foreign language learners and their characteristics,this paper illuminates that training on Language Learning Strategies in regular language classes helps foreign language learners become successful and independent learners.

Objective:To investigate the constituents of indole alkaloids in Ervatamia yunnanensis and their antiaddictive bioactivities. Methods: The preliminary alkaloids(TEYA) were extracted by 95% EtOH from the stems of Ervatamia yunnanensis.TEYA was then purified by silica gel and Sephadex LH20 column chromatography repeatedly and its structure was identified with spectral analysis.The antiaddictive effects of these indole alkaloids were evaluated by Conditioned Place Preference(CPP) experiments.Results: Nine indole alkaloids were obtained and identified as: coronaridine(1),voacangine(2),3-R-ethoxycoronaridine(3),3-S-ethoxycoronaridine(4), 19-epi-heyneanine(5),heyneanine(6),19-epi-voacristine(7),coronaridine hydroxyindolenine(8) and 12-methoxyl-voaphylline(9).Among them voacangine (2) and 19-epi-voacristine(7) were effective in prevention and treatment of addiction induced by morphine in rats(n=8).Conclusion: Compounds 3,4,8,and 9 have been isolated from Ervatamia yunnanensis for the first time and coronaridine-type indole alkaloids are the main antiaddictive constituents of E.yunnanensis.

Acute abdomen means a set of clinical emergency with acute abdominalgia as the primary characteristic symptom of onset,including others as the acute onset,quick symptom changes,severe illness,and oftenly need surgical treatment;therefore,acute abdomen ought to be designated within surgery domain.As interventional therapy is extensively applied in clinical medicine,now a days many victims of acute abdomen,especially those with ambiguous clinical diagnosis requiring an initial invasive examination(angiography,PTC,etc),should be referred to interventional therapy before taking an item of invasive measures.This new concept management has achieved good clinical curative effect and become one of the remarkable achievements in acute abdomen therapeutics.Such predominance finds proper expression in the following two aspects:(1)The evolution of contemporary medical iconography has made it possible to duely and accurately diagnose acute abdomen,and thus created a diagnostic predominance for us-interventionalists;(2)Intervention therapy is featured with its unigue minimal invasion and massive effectiveness,and thus provides high leading edge than conventional surgical operation.We believe that intervention management ought to become the first-choice for treating the above mentioned acute abdomen.(J Intervent Radiol,2006,15:193-194)

Objective:Toexplore the changes and mechanismofErythrocyte ImmunityFunction(EIF)in rats with Traumatic Brain Injury(TBI).Methods:HealthyWistar rat(sn=70)were divided intocontrol group(n=10)and TBI group(n=60),model ofTBI were prepared and divided into mild group(n=30)and moderate to severe group(n=30).Red Blood Cell-C3b Receptor Rate(RBC-C3bRR)and Red Blood Cell-Immune Complex Rate(RBC-ICR)of rats with TBI were measured by methed of yeast fungus and the content of serum ?-endophin(?-EP)was tested by radioimmunoassay.Results:Compared with the control group,RBC-C3bRR of rats with TBI decreased significantly while RBC-ICR and?-EP increased significantly(P

Objective:To investigate the expression and significance ofp16INK4a and HPV16/18 in atypical squamous cells of undetermined significance(ASC-US),atypical squamous cells,cannot exclude high-grade squamous intraepithelial lesion(ASC-H),low-grade squamous intraepithelial lesion(LSIL),high-grade squamous intraepithelial lesion(HSIL).Methods:p16INK4a and HPV16/18 DNA in thin-layer slides from 89 specimens were detected by immunohistochemistry and the insitu hybridization.Results:A positive correlation was found between the positive rate of p16INK4a and cervical disease progression,the positive rate of p16INK4a in LSIL,HSIL,ASC-H were higher than ASC-US(P

OBJECTIVE To observe the effect of Anerdian on operation field disinfection instead of iodine tincture.METHODS Totally 40 354 surgical patients used Anerdian during from Jan 2005 to May 2007 were studied in comparison with 15 840 cases used iodine tincture during 2004.RESULTS There was no significant difference in disinfection effect between Anerdian and iodine tincture.CONCLUSIONS Anerdian is an effective,convenient and available disinfectant for operation field disinfection.