1.Research of laparoscopic radical cystectomy and urinary diversion.
Chinese Journal of Surgery 2008;46(24):1865-1867
2.Advance in pathogenesis and therapy of pediatric dilated cardiomyopathy
International Journal of Pediatrics 2011;38(2):169-172
Dilated cardiomyopathy (DCM) is the most commom form of cardiomyopathy in children,including genetic and non-genetic pathogenesis. Due to the unclear aetiology and pathogenesis, DCM seriously impairs the quality of patients' life and reduces patients' survival time. Heart failure is one of the main clinical manifestations of DCM. Carvedilol, the third generation of β-adrenergic receptor blocker, is a nonselective β-blocker and a selective α1-blocker as well. It can prevent the development of ventricular remodeling and improve myocardial contractility and has been widely used in treating chronic cardiac insufficiency in adults. This article summarized some new progresses in pathogenesis and therapy of pediatric dilated cardiomyopathy.
3.The relationship and clinical significance of proBNP (NT-proBNP)in patients with angina pectoris
Journal of Chinese Physician 2015;(z2):20-21
Objective To investigate the relationship and clinical value of proBNP (NT-proBNP), serum tumor necrosis factor (N)and serum tumor necrosis factor (TNF)in patients with angina pectoris. Methods Sixty cases of patients with angina pectoris in our hospital as the research object,according to the type of disease in patients divided into unstable angina pectoris group and stable angina group,30 cases in each group;elect the hospital over the same period a routine examination of the normal population 30 ca-ses of normal control group were measured in each group of NT proBNP and serum TNF alpha concentration, and the correlation analysis was performed.Results The plasma NT-proBNP concentrations in patients with LEVF were significantly higher than those in healthy people (P <0.05).The serum concentrations of TNF-in patients with stable and unstable angina were not significantly different (P >0.05).The plasma NT-proBNP concentrations in patients with LEVF were significantly higher than those in LEVF patients (P<0.05).Conclusions NT-proBNP in plasma of patients with unstable angina pectoris,whether LEVF is normal or not,has a certain level of serum TNF-α.
4.Research on the application of the internet medical in hospital
China Medical Equipment 2016;13(3):101-104
Objective:To optimize the hospital outpatient service, solve the problem of poor outpatient queuing and poor medical experience, combined with Mobile Internet Technology to build a mobile application of outpatient services, and achieve the patient as the center of the O2O outpatient service process.Methods: The Hospital Information System be as the basis, with the help of The Service Windows Platform of Alipay, launching The Friendship Hospital Service Window which is a mobile internet medical application. Focus on its technical architecture, functional design and key technical aspects of the analysis.Results: The Friendship Hospital Service Window achieved the transformation of outpatient treatment process, significantly reduced the invalid waiting time for outpatient patients, reduced the hospital labor costs, improved the efficiency of outpatient clinic service.Conclusion: Mobile internet technology application in the outpatient service, improves the patient medical experience, improves the hospital image, inputs new vitality to the development of the hospital.
5.Stem cells for the treatment of glaucoma
Recent Advances in Ophthalmology 2017;37(9):886-889
Glaucoma is a kind of disease with irreversible degeneration of optic nerve and visual field defects,and the mechanism of optic nerve injury caused by glaucoma has undefined at present;meanwhile,the treatment of glaucoma has not been achieving satisfying outcomes in clinical practices.It has been well known that stem cells have the ability to self-proliferate and differentiate.Recently,with the deepening of stem cell research,it is possible for humans to use stem cells to treat glaucoma.There are two methods of stem cell transplantation for glaucoma:stem cell replacement therapy for trabecular meshwork and retinal ganglion cell replacement therapy,so this article will give a review on the progress of stem cells in the treatment of glaucoma.
6.Effect of 5-Aza-CdR on RUNX3 expression and the proliferation of human hepatocarcinoma cell line HepG2
Basic & Clinical Medicine 2006;0(03):-
Objective To investingate the effect of 5-Aza2'-deoxycytidine(5-Aza-CdR)on cell growth and to explore the possibility of re-expression of the hypermethylated and silenced RUNX3 gene in hepatocarcinoma cell line HepG2.Methods The change in expression of the tumor suppressor gene RUNX3 mRNA in cultured HepG2 cells was observed by RT-PCR before and after 5-Aza-CdR treatment.Activity of cell growth was observed by MTT assay and colony-forming test.The cell cycle was analyzed by flow cytometry.Apoptotic morphology was observed by transmitting electron microscopy.Results The gene was reactivated by two different doses of 5-Aza-CdR treatment in HepG2 cell without expressing RUNX3.The hepatocarcinoma cell line treated with 5-Aza-CdR displayed a slowed growth rate in contrast to the control group.The colony formation rate of HepG2 cell treated with 5-Aza-CdR decreased dramatically(P
7.A pilot research on the influence of psychological of the patients who received radiotherapy using position immobility by thermoplastic sheet
China Medical Equipment 2015;(10):103-105
Objective:To explore the influence of psychological and to identify determinants for patients using position immobility by thermoplastic sheet in the course of radiotherapy. Methods:55 patients who received radiotherapy using position immobility by thermoplastic sheet were investigated with questionnaires. Results:There are 34.5%(19/55) patients admit under psychological stress during the treatment, which were affected by the tension from doctors’ consultation and the chemotherapy experience. Conclusion:Some patients were under psychological stress caused by the position immobility with thermoplastic sheet. Nursing intervention is necessary to improve, especially to the patients who show stress when consultation with doctors and who had chemotherapy experience.
8.Research progress on role of Wnt signaling pathway in regulation of tumors
Chinese Pharmacological Bulletin 2017;33(1):14-17,18
Wnt signaling pathway is a highly conservative signal pathway controlling cell growth,differentiation,apoptosis and self-renewal.This signal pathway is often abnormally activated in tumor development and progression,which can cooperate or antagonize with other signal pathways to regulate tumor prolifera-tion,migration and invasion.This paper makes a review of the recent research of Wnt signaling pathway progression and its function in tumor growth regulation.
9.Shu-needling at Xiaguan (ST 7) for 35 cases of primary sciatica.
Chinese Acupuncture & Moxibustion 2015;35(9):889-890
Acupuncture Points
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Acupuncture Therapy
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Aged
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therapy
10.Study of Risk Factors of Nosocomial Infection in Intracerebral Hemorrhage
Chinese Journal of Nosocomiology 2001;11(1):4-6
OBJECTIVE In order to explore and control the risk factors of nosocomial infection in intracerebral hemorrhage.METHODS To study prospectively in 837 hospitalized patients with intracerebral hemorrhage in our hospital from Jan.1997 to June 1999. RESULTS It was showed 215 cases of the nosocomial infection were found among 837 cases with the intracerebral hemorrhage(25.8%).Among them,nosocomial lower respiratory tract infection was the highest(39.1%),the second one was the urinary tract(27.8%).Nosocomial infection was closely related with such factors as the aging,location and volume of intracerebral hematoma,disturbance of consciousness, smoking,blood sugar,invasive operation,antibiotic prophylaxis,bed-days.Whereas serum cholesterol was a protective factor.CONCLUSIONS Nosocomial infection was still a high frequent complication in intracerebral hemorrhage and it should be paid attention.This is the most important step to control nosocomial infection of intracerebral hemorrhage in the hospital.