Objective:To study the risk factors and treatment of lymphatic fistulas after the radical operation of gastric cancer.Methods:Observed the clinical data of 631 cases after the radical operation of gastric cancer that had been received in our hospital from February 1998 to February 2008.Multiple factor analysis with logistic regression was performed for the risk factors.Results:The level of post-operative serum albumin on the first day and Ultrasonically activated shears are protective facrors against lymphatic fistulas(P

OBJECTIVE:To distinguish between the traditional science of Chinese materia medica and the pharmacognosy and discuss the developmental direction of the traditional Chinese medicine.METHODS:The differences between the traditional science of Chinese materia medica and the pharmacognosy in rationale,research contents,medical treatment principles and identification of the quality of the traditional Chinese medicine were compared to clarify that the pharmacognosy and traditional science of Chinese materia medica are completely different concepts.RESULTS:At present,the science of Chinese materia medica is constrained by the theory of pharmacognosy,and the traditional science of Chinese materia medica is tended to be gradually replaced by the western-medicine-theory-based pharmacognosy.CONCLUSION:It is necessary to reconsider and discuss the developmental direction of the traditional Chinese medicine.Modern research on Chinese medicine should follow the natural laws of the Chinese medicine itself rather than following the development mode of the western medicines.

Objective To investigate the clinical value of 6‐indicator of albumin ,alpha 1 globulin ,alpha 2 globulin ,beta 1 globu‐lin ,beta 2 globulin and gamma globulin detected by the automatic capillary serum protein electrophoresis in liver cancer disease . Methods Eighty‐three hospitalized patients(51 cases of primary liver cancer and 32 cases of secondary liver cancer) in our hospital from December 2014 to November 2015 were collected .The automatic biochemical analyzer and automatic capillary serum protein e‐lectrophoresis was adopted to detect the 8 indicators of serum albumin(g/L for quantitative indicator and % for qualitative indica‐tor) ,total protein ,alpha 1 globulin ,alpha 2 globulin ,beta 1 globulin ,beta 2 globulin ,gamma globulin .And 100 individuals undergo‐ing the healthy physical examination were randomly extracted as the control group .The levels of above 8 indicators were compared among various groups .Results The level of albumin(% ) and gamma globulin had statistical difference between the primary liver cancer group before treatment and the control group(P<0 .05);the levels of albumin(g/L) ,albumin(% ) ,beta 1 globulin and gam‐ma globulin had statistical difference between the primary liver cancer group after treatment and the control group(P<0 .05);the levels of albumin(g/L) and albumin(% ) after treatment in the primary liver cancer group were decreased compared with before treatment ,the difference was statistical difference(P<0 .05);the sensitivity and specificity of gamma globulin for indicating primary liver cancer were significantly higher than those of the other three indicators;at the same time in the comparison of the positive rate of serum gamma globulin ,the positive rate of serum gamma globulin in the primary liver cancer group was higher than that in the secondary liver cancer group and the control group(P<0 .05) .Conclusion The automatic capillary serum protein electrophoresis detection finds that gamma globulin has some clinical value in the diagnosis and treatment of liver cancer .

The paper overviewed the research progress of the upper limb rehabilitation training system based on virtual reality technology,introduced some kinds of rehabilitation system, especially the software design, and the application of virtual scene, virtual object and network remote in the upper limb rehabilitation, and summarized the problem of applications of virtual reality in the rehabilitation and put forward the prospects about it.

OBJECTIVETo explore the value of the application of oil red O staining in spinal cord injury (SCI) of rats.

METHODSWith simple randomization, 24 Spargue-Dawley male rats were divided into normal control group including 6, and SCI group including 18. Spinal cord was transected at spinal lever T10 to build SCI model. Six rats of SCI group were sacrificed randomly at 1, 2, 4 weeks after surgery. After the spinal cord tissue sections were made, oil red O staining methods were used to observe the changes at the end of transected spinal cord. Images were analyzed by Image-Pro Plus 6.0 and SPSS 20.0 software.

RESULTSThe oil red O staining of normal control group showed that white matter surrounded by myelin sheath was clear and obviously distinctive from grey matter. Uneven and strengthened staining in oil O was observed in grey matter of SCI group at 1, 2, 4 weeks post-SCI.

CONCLUSIONIt is a good method to label the myelin sheath in spinal cord and distinct white matter from grey matter by oil red O staining. Analysis of the images showed that lipid may become another target for drugs, which needs more researches.

Animals ; Azo Compounds ; Gray Matter ; pathology ; Male ; Nerve Fibers ; physiology ; Nerve Regeneration ; Rats ; Rats, Sprague-Dawley ; Spinal Cord Injuries ; pathology ; Staining and Labeling

Sorafenib is a molecular targeted drug for the treatment of advanced primary liver cancer.However,along with the occurrence of drug resistance,the therapeutic effect was effected.At present,there is clear evidence that the emergence of drug resistance of live cancer is closely related to the epithelial-mesenchymal transition,liver cancer stem cells and the heterogeneity of liver cancer,and the PI3K/AKt signaling pathway as the vital common signaling channel was involved in the above mentioned process.From this we can conclude that complementary inhibtion of PI3K/AKt signaling pathway at the same time is the method that can strengthen the effect of sorafenib on the treatment of liver cancer so far.

The metabolic syndrome represents a complex combination of the symptoms obesity, hypertension, diabetes, and dyslipoproteinemia. Insulin resistance is the major pathophysiologjcal basis of the metabolic syndrome. There is a close association between the metabolic syndrome and its various components and vascular cognitive impairment. This article briefly reviews the mechanisms of metabolic syndrome caused vascular cognitive impairment, and summarizes the significance of controlling metabolic syndrome on the prevention and treatment of vascular cognitive impairment.

ObjectiveTo study the relationship between EphA2 and laryngeal carcinoma angionegesis.MethodsImmunohistochemical staining was used to determine the expression of EphA2 and CD34 in 20 normal squamous epithelium tissues and 50 laryngeal carcinoma.The relationship between EphA2 expression and Microvascular density was analyzed bg Spearman correlation and linear regression.ResultsThe MVD in laryngeal carcinoma (54.89 ± 13.67) was significantly higher than that in normal squamous epithelial tissues ( 17.15 ± 5.21 ) ; The EphA2 in laryngeal carcinoma(4.56 ± 1.38) was significantly higher than that in normal squamous epithelial tissues ( 2.49 ± 1.23 ) ( t =16.721,5.847,all P ＜ 0.05 ).There was significant positive linear correlation between EphA2 and MVD in laryngeal squamous cell carcinoma(P ＜ 0.01 ).ConclusionEphA2 may correlate with angionegesis in laryngeal squamous cell carcinoma.

Objective To observe the clinical effect of Shenqiluotong capsule on diabetes mellitus crura angiopathy.Methods Two hundred patients with diabetes mellitus crura angiopathy were randomly divided into two groups.One hundred patients in the treatment group were administrated Shenqiluotong capsule and enteric-coated aspirin tablet orally.One hundred patients in the control group were only given enteric-coated aspirin tablet orally.The effectiveness,clinical symptom and sign,glucose,blood fat,hemodynamics,crura artery diameter,peak value rate,blood flow volume and side effect were observed before and after treatment.Results The total effective rate in the treatment group and the control group were 89 % and 71% respectively(P

Objective Investigate MR resonance diffusion tensor im-aging (DTI) characteristics of non-pyramid tracts in the patients with amyotrophic lateral sclerosis(ALS). Methods 21 patients with ALS were served as case group.20 healthy volunteers were served as healthy controls. All subjects underwent a DTI sequence, chose region of interest (ROI) to measure fractional anisotropy (FA) and mean diffusivity (MD).Results In case group, FA decreased on the splenium of corpus callosum (0.73?0.087)(u=-2.004,P