Objective To investigate the clinical value of 6‐indicator of albumin ,alpha 1 globulin ,alpha 2 globulin ,beta 1 globu‐lin ,beta 2 globulin and gamma globulin detected by the automatic capillary serum protein electrophoresis in liver cancer disease . Methods Eighty‐three hospitalized patients(51 cases of primary liver cancer and 32 cases of secondary liver cancer) in our hospital from December 2014 to November 2015 were collected .The automatic biochemical analyzer and automatic capillary serum protein e‐lectrophoresis was adopted to detect the 8 indicators of serum albumin(g/L for quantitative indicator and % for qualitative indica‐tor) ,total protein ,alpha 1 globulin ,alpha 2 globulin ,beta 1 globulin ,beta 2 globulin ,gamma globulin .And 100 individuals undergo‐ing the healthy physical examination were randomly extracted as the control group .The levels of above 8 indicators were compared among various groups .Results The level of albumin(% ) and gamma globulin had statistical difference between the primary liver cancer group before treatment and the control group(P<0 .05);the levels of albumin(g/L) ,albumin(% ) ,beta 1 globulin and gam‐ma globulin had statistical difference between the primary liver cancer group after treatment and the control group(P<0 .05);the levels of albumin(g/L) and albumin(% ) after treatment in the primary liver cancer group were decreased compared with before treatment ,the difference was statistical difference(P<0 .05);the sensitivity and specificity of gamma globulin for indicating primary liver cancer were significantly higher than those of the other three indicators;at the same time in the comparison of the positive rate of serum gamma globulin ,the positive rate of serum gamma globulin in the primary liver cancer group was higher than that in the secondary liver cancer group and the control group(P<0 .05) .Conclusion The automatic capillary serum protein electrophoresis detection finds that gamma globulin has some clinical value in the diagnosis and treatment of liver cancer .

OBJECTIVE:To distinguish between the traditional science of Chinese materia medica and the pharmacognosy and discuss the developmental direction of the traditional Chinese medicine.METHODS:The differences between the traditional science of Chinese materia medica and the pharmacognosy in rationale,research contents,medical treatment principles and identification of the quality of the traditional Chinese medicine were compared to clarify that the pharmacognosy and traditional science of Chinese materia medica are completely different concepts.RESULTS:At present,the science of Chinese materia medica is constrained by the theory of pharmacognosy,and the traditional science of Chinese materia medica is tended to be gradually replaced by the western-medicine-theory-based pharmacognosy.CONCLUSION:It is necessary to reconsider and discuss the developmental direction of the traditional Chinese medicine.Modern research on Chinese medicine should follow the natural laws of the Chinese medicine itself rather than following the development mode of the western medicines.

The paper overviewed the research progress of the upper limb rehabilitation training system based on virtual reality technology,introduced some kinds of rehabilitation system, especially the software design, and the application of virtual scene, virtual object and network remote in the upper limb rehabilitation, and summarized the problem of applications of virtual reality in the rehabilitation and put forward the prospects about it.

Objective:To study the risk factors and treatment of lymphatic fistulas after the radical operation of gastric cancer.Methods:Observed the clinical data of 631 cases after the radical operation of gastric cancer that had been received in our hospital from February 1998 to February 2008.Multiple factor analysis with logistic regression was performed for the risk factors.Results:The level of post-operative serum albumin on the first day and Ultrasonically activated shears are protective facrors against lymphatic fistulas(P

Sorafenib is a molecular targeted drug for the treatment of advanced primary liver cancer.However,along with the occurrence of drug resistance,the therapeutic effect was effected.At present,there is clear evidence that the emergence of drug resistance of live cancer is closely related to the epithelial-mesenchymal transition,liver cancer stem cells and the heterogeneity of liver cancer,and the PI3K/AKt signaling pathway as the vital common signaling channel was involved in the above mentioned process.From this we can conclude that complementary inhibtion of PI3K/AKt signaling pathway at the same time is the method that can strengthen the effect of sorafenib on the treatment of liver cancer so far.

Objective To develop a system for hand function evaluation and training based on virtual reality. Methods 5DT Data Glove 5 Ultra, Visual Studio 2010 were integrated as the development environment and DirectX 9.0 as components, and the system was developed based on the MFC programming framework. Results and Conclusion The system can assess the fingers function, recognise gestures and can be used as a 3D environment for virtual training, which may guide the patients to take the training actively.

In the present study, platelet GSH_(px), SOD activities and cAMP contents, as well as whole blood, erythrocyte, plasma and hair selenium levels were comparatively measured in children from Keshan disease endemic and non-endemic areas. The results showed that blood and hair selenium contents were significantly lower in children of the endemic area than in those of the non-endemic area; children in the endemic area had a signifi cantly lower platelet GSH_(px) activities as compared to those in the non-endemic area, but no remarkable difference of platelet SOD activities and cAMP contents between children in the two areas was observed. The results indicate that the reduced GSH_(px) activity of low-selenium children in the endemic area may result in alterations in platelet functions and arachidonic acid metabolism.

The metabolic syndrome represents a complex combination of the symptoms obesity, hypertension, diabetes, and dyslipoproteinemia. Insulin resistance is the major pathophysiologjcal basis of the metabolic syndrome. There is a close association between the metabolic syndrome and its various components and vascular cognitive impairment. This article briefly reviews the mechanisms of metabolic syndrome caused vascular cognitive impairment, and summarizes the significance of controlling metabolic syndrome on the prevention and treatment of vascular cognitive impairment.

Objective To explore the effect of drug injection in muscle motor points on children with spastic cerebral palsy. Methods 230 children with spastic cerebral palsy were divided into control group and observation group, with 115 cases in each group. The control group received comprehensive rehabilitation including functional training, physical therapy and medicine, while the observation group received injection of vitamin B1 and vitamin B12 in muscle motor points in addition. They were assessed with Gross Motor Function Measure (GMFM), modified Ashworth Scale (MAS), mental development index (MDI) and psychomoter developmental index (PDI) of CDCC Infant Me Ntal Development Scale. Results The gross motor function improved, MAS score decreased, the scores of MDI and PDI increased after treatment (P<0.01) in both groups, which were better in the observation group than in the control group (P<0.05). Conclusion Drug injection in muscle motor points can improve the gross motor function, relieve spasm, and improve intelligence development of children with spastic cerebral palsy.

OBJECTIVETo explore the value of the application of oil red O staining in spinal cord injury (SCI) of rats.

METHODSWith simple randomization, 24 Spargue-Dawley male rats were divided into normal control group including 6, and SCI group including 18. Spinal cord was transected at spinal lever T10 to build SCI model. Six rats of SCI group were sacrificed randomly at 1, 2, 4 weeks after surgery. After the spinal cord tissue sections were made, oil red O staining methods were used to observe the changes at the end of transected spinal cord. Images were analyzed by Image-Pro Plus 6.0 and SPSS 20.0 software.

RESULTSThe oil red O staining of normal control group showed that white matter surrounded by myelin sheath was clear and obviously distinctive from grey matter. Uneven and strengthened staining in oil O was observed in grey matter of SCI group at 1, 2, 4 weeks post-SCI.

CONCLUSIONIt is a good method to label the myelin sheath in spinal cord and distinct white matter from grey matter by oil red O staining. Analysis of the images showed that lipid may become another target for drugs, which needs more researches.

Animals ; Azo Compounds ; Gray Matter ; pathology ; Male ; Nerve Fibers ; physiology ; Nerve Regeneration ; Rats ; Rats, Sprague-Dawley ; Spinal Cord Injuries ; pathology ; Staining and Labeling