1.The surrent situation and prospect about design and implementation of forensic clinical medicine standards ;in China(
Chinese Journal of Forensic Medicine 2016;31(5):433-436
Technical standards were supports that not only for any profession’s development, but also for the basic means of modern quality control.Forensic clinical medicine has developed nearly 40 years in china, there are 23 normative technical documents at present, the range of its application has been expanding with time, the caseload has been more than 1 million pieces per year all the country. Reviewing these standards, it can be seen: Technital standard of forensic clinical medicine has absorbed a large number of advanced international ideas, assimilating plenty of practice experience at the same time, standard's system has been initially formed, it has become one of the important means to guarantee the quality of medicolegal expertise. Certainly, the construction of forensic clinical standardization in China is still an arduous task, there are also many outstanding contradiction in the existing standards, our studies on international standards were not in-depth, and so on. In the future, forensic science experts still need to strengthen the companion study of technical standards and laws or regulations, intensify tracing and evaluating of international standards in order to form more adaptive and advanced technical standards.
2.Grow with care and efforts.
Chinese Journal of Burns 2006;22(1):4-4
4.Research progress on regulatory mechanism of liver cancer stem cells
Chinese Journal of Hepatobiliary Surgery 2014;20(12):900-904
The theory of cancer stem cells proposed that recurrence and metastasis of liver cancer are closely related to liver cancer stem cells.The traditional surgical treatment of liver cancer simply kills those rapidly proliferating tunor cells instead of eliminating hepatic cancer stem cells which play decisive role in recurrence and metastasis.As far as people have concerned,there are many signaling pathways and regulatory factors modulating liver cancer stem cells,such as the Wnt/β-catenin pathway,TGF-β pathway,Notch pathway,Hedgehog pathway,hepatitis B virus,as well as epigenetics.Further studies on regulatory mechanisms of liver cancer stem cells are of great significance,in hope of providing new evidence for treatment and prevention of recurrence and metastasis of liver cancer.
5.Relationship Between Tumor Angiogenesis and Expression of Vascular Endothelial Growth Factor and Nitric Oxide Synthase in Human Gastric Cancer
Chinese Journal of Bases and Clinics in General Surgery 2004;0(01):-
Objective To study the expression of inducible nitric oxide synthase (iNOS),endothelial nitric oxide synthase (eNOS) and vascular endothelial growth factor (VEGF) in human gastric cancer and their relationship with tumor angiogenesis and to investigate the interaction of NOS and VEGF in gastric cancer.Methods The expression and distribution of VEGF, iNOS and eNOS in 34 gastric cancer specimens were detected with immunohistochemistry. Microvessel density (MVD) was counted with FⅧRAg immune specific staining.Results The expression rates of iNOS, eNOS and VEGF in 34 gastric cancers were 73.5%, 82.4%and 91.2%respectively. The expression of VEGF had a significant positive relation with iNOS, but not with eNOS. The MVDs of VEGF or iNOS positive gastric cancers were obviously higher than those of VEGF or iNOS negative gastric cancers. There was no significant difference between the MVDs of eNOS positive gastric cancers and eNOS negative ones. Conclusion MVD increases with increase of expression of VEGF and iNOS in gastric cancer. It is indicated that VEGF and iNOS can promote gastric cancer angiogenesis. VEGF and iNOS have a significant positive correlation, which suggests that in human gastric cancer, iNOS plays an important role in the production and action of VEGF.
6.Application of microperimeter in the visual function evaluation.
Journal of Forensic Medicine 2014;30(3):194-196
In condition of direct vision on hindus of eye, microperimeter can quantitatively detect the retinal light sensitivity of macular area, and record real time tracking of the eye, automatically analyze the location and stability of fixation. Microperimeter matches hindus image with micro cyclogram point-to-point, thus it achieves the combination of visual function and structure. The characteristics of microperimeter have good relations with subjective vision, so it can be a new method for the accurate vision evaluation and has application potential to assess the visual function in legal medicine. In this article, we summarize the principle, method and parameters of microperimeter. Also, the applications of microperimeter in vision assessment are focused in order to provide a reference for the assessment of visual function in the legal medicine.
Forensic Medicine/legislation & jurisprudence*
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Humans
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Retina
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Vision, Ocular
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Visual Acuity
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Visual Field Tests
7.Assistive Devices for Persons with Disability and Supply Service
Chinese Journal of Rehabilitation Theory and Practice 2007;13(4):321-323
The authors discussed the development of the assistive devices and service in China and overseas by analyzing the calssification, function, demand and difference between China and other countries.
8.Comparison on Criteria of Impairment Evaluation about Eye Injury
Chinese Journal of Rehabilitation Theory and Practice 2007;13(8):769-771
Objective To compare and investigate the criteria of impairment evaluation about eye injury.MethodsThe distill items, contents of these items and excursus of three criteria, Assessment and Gradation of Disability Caused by Work-related Injuries and Occupational Diseases (AGDCWIOD), Assessment for Body Impairment of the Injured in Road Traffic Accident (ABIIRTA) and Assessment and Gradation of Impairment Caused by Trauma (AGICT), commonly used in justice practice at present were compared.ResultsThere were essential differences among three criteria. AGDCWIOD was loose, ABIIRTA and AGICT were strict. AGDCWIOD and AGICT were religious, ABOIIRTA was oversight and non-religious. At the same time, there were differences between domestic and international criteria, and domestic criteria were behind the times.ConclusionThere are many problems in the criteria of impairment evaluation about eye injury; related items need recension and consummation.
9.The research progress of DNA methylation in bladder cancer
Chinese Journal of Urology 2021;42(4):312-315
Bladder cancer is a malignant tumor of the urinary system with the highest and still increasing incidence rate in China in recent years. While most patients with a diagnosis of non-muscle invasive bladder cancer (NMIBC) have a good prognosis, NMIBC is prone to relapse and progress to muscular invasive cancer (MIBC) after treatment, leading to a poor prognosis. At present, diagnosis and postoperative follow-up of bladder cancer still rely on invasive cystoscopy, and there is a lack of effective treatment for advanced tumors. The results show that methylation, as a chemical modification of DNA, is related to the occurrence and development of bladder cancers. This article reviews the research progress of bladder cancer DNA methylation in diagnosis, monitoring and treatment in recent years.
10.Research progress of nerve repair in the treatment of peripheral facial paralysis
Chinese Journal of Microsurgery 2021;44(1):118-120
At present, the surgical treatment of peripheral facial paralysis includes non-dynamic and dynamic treatment. The former suspends the facial soft tissue with various materials to reconstruct the static symmetry of the face. The latter, through nerve repair and the transplantation of vascularized neuromuscular flap, restores the facial nerve and expressive muscle contractile function of the affected side, to achieve the ideal therapeutic effect. This article summarises the relevant literatures, reviews the application of various nerve repair methods in peripheral facial paralysis, to discusses the scope of application, advantages and disadvantages, and provides reference and help for clinicians in selection of surgical methods for peripheral facial paralysis.