Flail chest is the common chest trauma, which causes abnormal respiration and mediastinal swing affecting the respiratory and circulatory function after injury. Fixation of ribs of flail chest has been used for half a century, methods and equipment of which varied, and domestic and foreign scholars have verified its efficacy in clinical practice. This article summarizes its main great progresses.

Antineoplastic Agents, Hormonal ; therapeutic use ; Antineoplastic Agents, Phytogenic ; therapeutic use ; Breast Neoplasms ; drug therapy ; prevention & control ; secondary ; surgery ; Chemotherapy, Adjuvant ; methods ; Early Detection of Cancer ; methods ; Female ; Humans ; Tamoxifen ; therapeutic use ; Taxoids ; therapeutic use

Anthracyclines ; pharmacology ; therapeutic use ; Antineoplastic Combined Chemotherapy Protocols ; therapeutic use ; Breast Neoplasms ; drug therapy ; metabolism ; Cisplatin ; administration & dosage ; Deoxycytidine ; administration & dosage ; analogs & derivatives ; Drug Resistance, Neoplasm ; Female ; Humans ; Taxoids ; administration & dosage ; Vinblastine ; administration & dosage ; analogs & derivatives

Pit cells (PCs) are hepatic natural killer cells(HNKCs), and play an important role in resisting tumor, resisting virus, regulating hepatocyte growth and differentiation, inhibiting liver fibrosis and so on. In the paper, research progress in liver pit cells is briefly summarized.

Objective To study the CT characteristics of inflammatory pseudotumor of the liver(IPL).Methods 16-slice spiral CT findings of IPL in 16 cases were analysed retrospectively.The CT values of IPLs and the liver tissue surrounding the lesions were measured on plain and contrast-enhanced CT scans.Results Totally 18 lesions in 16 cases were detected by CT,most of them(16 lesions) located in the right lobes of liver.The lesions appeared as low-density,round or round-like,or irregularity in sharp.Dynamic enhanced CT scan showed the lesions no or slight enhancement in arterial phase,slight to moderate enhancement in portal vein phase.A part of the lesions showed ring enhancement surrounding the lesions,nodular or fiber stripped enhancement in the center of lesions,and the branches of the portal vein passesed through the lesions.In enhanced degree of the lesions,there was not statistical difference in arterial phase compared with plain CT scans,but there were statistical differences in portal-venous phase compared with plain scan and arterial phase.In the liver around the lesion,the enhanced degree had statistical difference in artery phase and portal-vein phase compared with plain CT scans.Conclusion Dynamic enhanced CT scan shows that IPL is of hypovascularity,it's of characteristic in the portal-venous phase and delayed phase.

This article sorts out and analyzes acupuncture-moxibustion items inTreatise on Cold Damage DiseasesandSynopsis of Prescriptions of the Golden Chamberand proposes regularities in application of and the characteristic ofZhangZhong-jing’s acupuncture and moxibustion. Acupuncture was often used for unblocking and regulating meridional qi and clearing and purging excessive heat. Moxibustion was often used for warming yang and remedying deficiency or dispersing and unblocking yang qi. Because of convenient operation, acupuncture-moxibustion therapy was often used to treatdangerous and serious diseases. Acupuncture and moxibustion were often combined with herbal prescriptions and other therapeutic methods to improve therapeutic effects, especially on difficult and complicated diseases.ZhangZhong-jing’s guiding thought ofacupuncture-moxibustion treatment first advocates treatment of diseases from the root and meanwhile, pays attention to treatment of both symptoms and causes of diseases. Secondarily, it emphasizes acupuncture-moxibustion treatment based on syndrome differentiation and especially values pulse condition, meridians and acupuncture points. It has abundant contents in treating the same disease with different methods and often selects specific acupoints. Thirdly, it favours preventive treatment of diseases, andwhether prevention of diseases before they arise or prevention of diseases from exacerbating was embodied in his acupuncture-moxibustion treatment.

Objective To observe the effect of oxymatrine on the Absorption of carbohydrate and fat and the activity of peroxisome proliferator activated receptor ? and ?.Methods 64 masculine SD rats were randomly divided into three groups,20 sugar tolerance test,20 triacylglycero Absorption test and 24 oxymatrine effecting on triacylglycero and cholesterin test,and observed the effect of oxymatrine on glycosidase activity,blood sugar and activity of peroxisome proliferator activated receptor ? and ?.Results ① The depressant effect of oxymatrine on the activity of glycosidase was strengthened by the increased dosage.② Oxymatrine could suppress the upgraded level of blood sugar after took amylon and cane-sugar,and inhibit the upgraded level of triacylglycerol after feed by olive oil and hypso-cholesterol,but did not suppress the upgraded level of blood sugar after took glucose and hardly influence the level of high density lipoprotein cholesterol and low density lipoprotein cholesterol.③ Oxymatrine could obviously activate the activity of peroxisome proliferator activated receptor ? and ?,the activity of peroxisome proliferator activated receptor ? and ? increased gradually by the augment of the oxymatrine,and expressed evident dose-response relation.Conclusions Oxymatrine could not only directly inhibit the Absorption of triacylglycerol and depress the elevated level of postprandial triacylglycerol,but also activate peroxisome proliferator activated receptor ?,moreover possess dose-response relation.

OBJECTIVE:To observe the therapeutic effect of compound glycyrrhizin injection on herpes zoster METHOD_S:50 cases of herpes zoster received compound glycyrrhizin injection 60ml q d intravenous drip for 5 days RESULTS:Curative rate was 22% and improving rate 64% with a total effective rate of 86% CONCLUSION:Compound glycyrrhizin has corticosteroid-like action,which could regulate immunologic function and inhibit virus

Competing endogenous RNAs (ceRNAs) transcripts can communicate with microRNAs (miRNAs) through competitively binding the common miRNA response elements (MREs),which remove or decrease the repression of target genes of miRNAs.The present studies indicate that a large amount of genes,serving as ceRNAs,can promote or inhibit the occurrence of liver cancer by competing the binding site of same genes that can promote or suppress tumorigenesis.

Integrins are a family of cell adhesion receptors that mediate cell-cell and cell-extracellular matrix adhesion, and interact with cytokines through a bidirectional signal transduction,thus regulating the biological behavior of pancreatic cancer cells,such as proliferation,apoptosis,invasion,and migration etc. Molecular and animal studies indicated that integrins targeted methods might benefit the early diagnosis and drug therapy of pancreatic cancer,which offered a new approach for the study of diagnosis and treatment of pancreatic cancer.