1.Effects of different reperfusion strategies on clinical outcome of ST-segment elevation myocardial ;infarction patients
Pingshuan DONG ; Zhijuan LI ; Hongqiang DUAN ; Laijing DU ; Honglei WANG ; Ke WANG ; Peng YAN ; Xiyan SHANG ; Ximei FAN ; Ruiqing LIU ; Qiuling ZHAI ; Baoxia XIANG
Chinese Journal of Interventional Cardiology 2014;(3):172-175
Objective To evaluate the outcome of ST-segment elevation myocardial infarction (STEMI) patients received different reperfusion therapies. Methods The 238 consecutive STEMI patients were enrolled from February 2012 to December 2012. According to the current guideline of PCI and the choice of patients, the patients were divided into the groups of percutaneous coronary intervention (PCI), ifbrinolysis, and conservative medication. The major adverse cardiac events (MACE) was analyzed in a follow up of 6 months. Results (1) The enrolled patients included the 210 patients received PCI (88.2%), 14 patients received fibrinolysis (5.9%) and 14 patients received conservative medication (5.9%).The Median time of D2B was 110minutes.(2) The rate of late stent thrombosis was signiifcant higher in BMS than DES (n=2, 2.8%vs 0, P < 0.05) . (3) The PCI group had a signiifcantly higher incidence of stroke than the ifbrinolysis group and the conservative medication group (1.0%vs 0, P < 0.05;1.0%vs 0, P<0.05). (4) The PCI group had a signiifcantly higher incidence of bleeding compared to the thrombolysis group and the medication group (1.0% vs 0, P < 0.05; 1.0% vs 0%, P < 0.05). Conclusions The majority of STEMI patients received PCI;The D2B time, which was required<90 minutes in guideline of PCI, was found delayed in our study;Compared to ifbrinolysis and conservative medication, PCI showed better clinical outcomes of STEMI patients.
2.Effect of antipsychotic drugs on life quality of schizophrenic patients: one year follow-up study.
Maosheng FANG ; Lehua LI ; Jingping ZHAO ; Honghui CHEN ; Meng YE ; Xiaofeng GUO ; Zheng LU ; Xueli SUN ; Chuanyue WANG ; Shiping XIE ; Bin HU ; Tiansheng GUO ; Cui MA ; Bo WANG ; Luxian LÜ ; Na LIU ; Hong DENG ; Qi CHEN ; Xiaofang SHANG ; Fajin GONG ; Xiyan ZHANG ; Xiaolin HE ; Jianchu ZHOU ; Yingli ZHANG
Journal of Central South University(Medical Sciences) 2009;34(9):850-855
OBJECTIVE:
To compare the effect of 7 antipsychotic drugs on the life quality of schizophrenia patients including chlorpromazine, sulpiride, clozapine, risperidone, olanzapine, quetiapine, and aripiprazole.
METHODS:
A total of 1,227 stable schizophrenic patients within 5 years onset who took 1 of the 7 study medications as maintenance treatment were followed up for 1 year at 10 China sites. Patients were evaluated by the short form-36 health survey (SF-36) at the baseline and at the end of 1 year.
RESULTS:
The life quality was improved obviously at the end of the follow-up. There was significant difference in body pain, vitality, and mental health (P<0.05) among these antipsychotic drugs.
CONCLUSION
All 7 antipsychotic drugs can improve the life quality of schizophrenia patients. Atypical antipsychotic drugs, especially olazapine and quetiapine, are superior to typical antipsychotic drugs in improving life quality.
Adolescent
;
Adult
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Antipsychotic Agents
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therapeutic use
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Benzodiazepines
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therapeutic use
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Dibenzothiazepines
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therapeutic use
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Female
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Follow-Up Studies
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Humans
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Male
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Middle Aged
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Olanzapine
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Quality of Life
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Quetiapine Fumarate
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Schizophrenia
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drug therapy
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Surveys and Questionnaires
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Young Adult
3.Penetration moxibustion with different dosage for insomnia of insufficiency of heart and spleen type.
Xiyan GAO ; Dongbin WANG ; Xinnian WANG ; Peiyu WANG ; Yali FAN ; Xinwang CHEN ; Ling GAO ; Shang MA ; Yajing GUO
Chinese Acupuncture & Moxibustion 2016;36(11):1139-1143
OBJECTIVETo observe the clinical efficacy differences between acupuncture combined with 40-min penetration moxibustion and 60-min penetration moxibustion at back-points for insomnia of insufficiency of heart and spleen type.
METHODSSixty patients of insomnia with insufficiency of heart and spleen type were randomly assigned into a 40-min group and a 60-min group. The two groups were treated with acupuncture at Jueyinshu (BL 14), Xinshu (BL 15), Geshu (BL 17), Pishu (BL 20), Shendao (GV 11) and Zhiyang (GV 9). With moxibustion box, the penetration moxibustion was applied at the back until sweating and redness on the back. The moxibustion was given for 40 min in the 40-min group and 60 min in the 60-min group. The treatment was given once a day, five days per week. Each session was consisted of 5 treatments, with an interval of 2 days between session and totally 4 consecutive weeks were provided. The Pittsburgh sleep quality index (PSQI), TCM symptom scale were observed and recorded before and after treatment in the two groups. The even temperature at raising period, effective period, reducing period, as well as minimum high temperature, comfortable temperature, minimum cold temperature and medication status were compared; also the effect was compared between the two groups.
RESULTSThe total effective rate was 96.6% (28/29) in the 60-min group, which was higher than 89.3% (25/28) in the 40-min group (<0.05). Compared before treatment, the total score of PSQI and sleep quality, sleep time, sleep efficiency, sleep disorder, daytime dysfunction as well as the total TCM symptom score and its drowsiress in the morning, palpitation, amnesia, appetite were reduced after treatment in the 40-min group (all<0.05). After treatment, the total score and each score of PSQI as well as total score and each score of TCM symptom scale were reduced after treatment in the 60-min group (all<0.05). After treatment, the total score and each score of PSQI as well as total score and each score of TCM symptom scale were significantly different between the two groups (all<0.05).
CONCLUSIONSAcupuncture combined with penetration moxibustion can improve the symptomsof insomnia with insufficiency of heart and spleen type, which is more significant in the 60-min group, indicating prolonged time of penetration moxibustion can improve sleep latency.
4.Brief discussion on technique and application experience of penetrating moxibustion.
Xiyan GAO ; Dongbin WANG ; Yajing GUO ; Ling GAO ; Shang MA ; Mengxia WEI ; Shuqi GE
Chinese Acupuncture & Moxibustion 2017;37(5):505-508
The penetrating moxibustion technique is proposed based on experience of the ancients and clinical practice for many years. From the aspects of definition, action characteristics and technique at different parts, the advantage and application experience of penetrating moxibustion have been discussed. The adequate dose of moxibustion is necessary in penetrating moxibustion; in addition, moxibustion sensation should be penetrating; therefore, with a temperature of 43℃ for more than 20 min, sweating, flushing, speckle appearing after penetrating moxibustion. Due to individual differences of age, gender and constitution factors, the effects of penetrating moxibustion are different, in clinical practice the body reaction and patient's feelings should be deliberately focused on other than does or sore and blister of moxibustion. The technique is common used in the abdomen, waist and knee joint, etc.