Objective:To study the possibility that responses of fever and c- Fos expression in rat PVN and NTS to intraperitoneal administration of LPS are rnediated by vagal afferents. Methods: Rectal temperature was detected by digital temperature detecting instrument. c-Fos expressis was detected by immunohistochemistry staining.Results:The rectal temperature change value in vagotomy LPS gnoup was significantlydecreased compared with that in sham IPS group,and there was striking difference betwen them, p ＜0.05.It was increased significantlycompared with that in vagotomy NS group, P ＜ 0.05.The percentage of c-Fos positive neurons in rat PVN and NTS in vagotomy LPS group wassignificantly decreased compared with that in sham LPS group,and there were difference between them, p ＜0.01.Itwas stnkingly increased compared with that in vagotomy conrol group,respectively, P ＜0.01.Conclusion:The results indicate that vagus nerve is one of thepathways of peripheal LPS signal communicating to CNS.

Objective:To study the possibility that responses of fever and c Fos expression in rat PVN and NTS to intraperitoneal administration of LPS are mediated by vagal afferents.Methods:Rectal temperature was detected by digital temperature detecting instrument.c Fos expression was detected by immunohistochemistry staining.Results:The rectal temperature change value in vagotomy LPS group was significantly decreased compared with that in sham LPS group,and there was striking difference between them,P

Purpose:To study the clinical value of percutaneous placement of biliary stents tbr treatment of malignant biliary obstruction.Materials and methods:A total of 58 stents were placed pereutaneously in 53 patients for palliative of malignant biliary obstruction. Results:The success rate of stent implantation was 98.1%(52/53).The difference between post-and pre-operation in the serum total bilirubin level of 52 patients was 182?67 ? mol/L,P

Objective To assess the effect of arterial embolization in treating hyperthroidism by colour ultrasonography.Methods Forty two cases of hyperthyroidism were treated with thyroid arteries embolization. A few days before and 1, 3, 6 months after embolization, the echograms of thyroids were observed including the volumes of thyroids and the internal diameters of thyroid arteries were measured with colour ultrasonography respectively. The Vs, Vd, Vm, PI, RI were measured with the Doppler and the quantities of blood flow were calculated. The relationships of changes for all these parameters and T 3, T 4 and TSH were analysed. Results Before artery embolization all thyroids were enlarged with diffusely homogenous or heterogenous low echos and nodules in some patients accompanied by widenings of the thyroid arteries and their branches full of blood supply. The volume of thyroids decreased after artery embolization. 1 3 months later the echo of thyroids enhanced and got coarse with decrease of the thyroid vasculature and narrowing of vessel calibers except a few star or spot like blood streams were sometimes seen within the thyroids and no blood flow signals found in some cases. 3 6 months after embolization, the echo of thyroids decreased gradually or unevenly distribnted. All the parameters of blood flow before and after the treatment showed statistically significant differences( P

Objective To investigate how internet using (both time and activities)and effortful control would contribute to the sex difference of problematic internet use (PIU).Methods A total of 844 adolescents aged 9-20 years old were selected from Chinese Academy of Sciences twin-sample by simple random sampling,with boys accounting for 45.6％ and girls accounting for 54.4％.The internet using and effortful control were measured using self-report questionnaires in the first time(T1),the problematic internet use were measured after one and half years (T2).The difference and relation of Internet using,effortful control and problematic internet use between boys and girls were measured with Chi-square test,t test and correlation analysis.The moderating effect of sex between internet using and PIU were explored by utilizing regression analysis.The mediation effect of effortful control between sex and PIU were explored with Sobel test.Results The anverage internet time of working day and weekend in boys were 1.52 h and 2.12 h respectively.The average internet time of working day and weekend in girls were 1.49 b and 2.05 h respectively.Significant difference between boys and girls is not existed in the internet time (t=0.541,0.907,P＞0.05).And the boy was inclined to game(x2 =47.669,P＜0.01).The effortful control of boys and girls were 54.09 and 55.76 respectively.The score of boys' and girls' PIU were 22.48 and 20.72 respectively.Boys' effortful control was significantly lower than that of girls (t=-2.879,P＜0.01).The score of boys' PIU was significantly higher than that of girls' (t=3.612,P＜0.01).Adolescents' PIU were significantly correlated with the time,entertainment and social activities (r=0.249,0.175,0.140,P＜0.01).The moderating effect of sex was significant in the relation between internet time and PIU.Significant mediation effect of effortful control existed in the PIU difference between boys and girls(Z=-2.54,P＜0.05).Conclusion Significant mediation effect of effortful control exists in gender and PIU.

In order to service clinical departments, reduce the cost and improve the efficiency of the storage, on the basis of information system, the overall planning of the requirement of frameworks and internal infrastructures of the hospital logistics center are proposed. The requirements of supplier admittance, the quality and the activities of the storage, the storage ratio of materials and the storage expense are discussed. It is pointed out that the integration management of logistics center, access control items, the reasonable management of storage materials, analyzing, evaluating and adjusting of various management indicators are effective methods of product quality assurance, reducing storage losses and monitoring costs.

Electroencephalogram(EEG) is necessary in diagnosis of status epilepticus (SE),particularly in non-convulsive SE with minor or atypical clinical manifestations.SE is a dynamic process,as seizures continue,in which EEG changed and appeared nonepileptic rhythm discharges.Ictal EEG patterns of SE are non-specific and different types of SE have different EEG features.In this paper,the EEG of different type SE will be summarized.

Objective To observe the improvement of postoperative pulmonary function and oxygen partial pressure during general anesthesia for open abdominal surgery with lung protective ventilation strategies and alveolar recruitment maneuvers. Methods Seventy patients who underwent selective open abdominal surgery were selected, and they were divided into standard ventilation group (tidal volume 8 ml/kg) and protective ventilation group (tidal volume 6 ml/kg, 5 cmH2O positive end-expiratory pressure, and alveolar recruitment maneuvers, 1 cmH2O=0.098 kPa) according to the random digits table method with 35 cases each. The airway pressure, blood pressure, pulse oxygen saturation (SpO2), end-tidal partial pressure of carbon dioxide (PETCO2) and adverse reactions were observed. The SpO2, partial pressure of O2 (PaO2) and pulmonary function before surgery and 1, 3, 5 d after surgery were measured. Results The respiratory rate, airway pressure and PETCO2 levels in protective ventilation group were significantly higher than those in standard ventilation group: (12.3 ± 2.1) times/min vs. (10.2 ± 1.0) times/min, (15.1 ± 2.8) cmH2O vs. (13.5 ± 2.3) cmH2O, (34.6 ± 2.1) mmHg (1 mmHg=0.133 kPa) vs. (32.1 ± 1.4) mmHg, and there were statistical differences (P<0.05). The SpO2 in 2 groups was maintained at 0.99. There was no statistical difference in the incidence of postoperative complications between 2 groups (P>0.05). The SpO2 and PaO2 levels at 1, 3 d after surgery in protective ventilation group were significantly higher than those in standard ventilation group:0.951 ± 0.018 vs. 0.936 ± 0.016 and 0.964 ± 0.018 vs. 0.949 ± 0.018, (74.8 ± 6.8) mmHg vs. (65.0 ± 6.2) mmHg and (79.6 ± 6.0) mmHg vs. (70.6 ± 5.3) mmHg, and there were statistical differences (P<0.05). The forced expiratory volume in 1 s (FEV1), percentage of the estimated value of FEV1, forced vital capacity (FVC) and percentage of the estimated value of FVC at 1, 3 and 5 d after surgery in protective ventilation group were significantly higher than those in standard ventilation group, the FEV1/FVC at 1 d after surgery was significantly higher than that in standard ventilation group, and there were statistical differences (P<0.05). Conclusions The lung protective ventilation strategy and alveolar recruitment maneuvers can improve the postoperative pulmonary function and oxygen partial pressure during general anesthesia for abdominal surgery. Low vital volume, appropriate positive end-expiratory pressure and recruitment maneuvers can protect the lung in general anesthesia patients.

Objective To understand postoperative experience for patients with relapsed bladder tumor and analyze its influence factors in order to supply references of postoperative nursing for nurses. Methods Patients with relapsed bladder tumot(10 cases) were interviewed and the obtained results underwent analysis and finishing thematically. Results Factors influencing postoperative experience included education haekground,whether having faith and hobbies or not,the disease,medical charge and pressure of future life.The supporting system came from family,group and society. Conclusions Nurses should strengthen mental care and health education based on patients' specific circumstances in order to improve postoperative quality of life.