Objective To reduce the rate of unscheduled nasogastric extubation for the patients in neurology department.Methods A nursing care team was set up for a thematic activity to reduce the rate of nasogastric tube unscheduled extubation.The team analysed the situations of 164 patients with nasogastric intubation in the neurology department,specifying the problems,deciding their aims and working out the strategies.Result The rate of unscheduled nasogastric extubation decreased from 19.63％ to 2.12％ and the rate of nursing omission decreased from 9.93％ to 2.59％ (P＜0.05).Conclusion The improvement activity of nursing projects can effectively reduce the rate of unscheduled nasogastric extubation and improve the quality of nursing care.

Objective To investigate the perceptions of medical staff about chemotherapeutic symptoms in children with leukemia.Method Sixty-one doctors and nurses were involved in the investigation using a self-designed questionnaire on uncomfortable symptom scale.Result The main symptoms of chemotherapy included hair loss,poor appetite,nausea,vomiting, oral mucositis and fatigue.Conclusion Chemotherapeutic symptoms are common in children with leukemia and need appropriate nursing management.

Objective To investigate the clinical features of the myelin oligodendrocyte glycoprotien antibody-associated disease(MOGAD).Methods The clinical data of 17 MOGAD patients who were hospitalized in The First Affiliated Hospital of Sun Yat-sen University from January 2017 to June 2019 were retrospectively analyzed.Then we summarized the clinical and imagine features of the MOGAD.Results Seventeen patients,including 11 males and 6 females,were recruited in this study,and the average age of onset was (27.76±12.22)years old.Ten patients presented as ON,9 cases manifested as myelitis,10 cases presented as the symptoms of brain damage,and 1 case as the ADEM.The MOG antibody in serum of 17 patients were positive,and the MOG antibody titers were from 1:10 to 1:320.Among them,the MOG antibody in cerebrospinal fluid of 7 patients were positive,and the antibody titers were from 1:1 to 1:32.Other autoimmune antibodies were positive in a small group of these patients.Magnetic resonance imaging(MRI) scan are abnormal in all the patients at onset.The majority lesions appear as poorly demarcated hyperintensities on T2-weighted and T2FLAIR images,some of them showed edge enhancement.All patients were treated with intravenous methylprednisolone,and 13 patients were treated with IVIG.The symptoms of 16 cases were improved within a month,and another case improved after the plasma exchange.And 6 cases recurred within a year.Conclusion The clinical features of the MOGAD were various,mainly including ON,myelitis,encephalitis,meningoencephalitis i.e.Early immunotherapy can result in having a complete or almost complete recovery.However,some patients had the risk of relapse.