Objective To explore the value of transvaginal combined with transabdominal ultrasound examination in diagnosing ectopic pregnancy. Methods The data of 68 cases with ectopic pregnancy examined by transabdominal ultrasound and then by transvaginal ultrasound were analyzed retrospectively. Results. Rates of discovering the diseases of combined examination were distinctly superior to that by any of the single examination. Conclusion Transvaginal combined with transabdominal ultrasound examination could improve accuracy in diagnosing ectopic pregnancy with high clinical merit.

The article summarized recent studies on the composition and activity analysis,as well as the clinical application and mechanism of citrus aurantium and its prescriptions,in an attempt to provide theoretical evidence for the clinical application of citrus aurantium on improving gastrointestinal motility.

Cytokeratins can maintain the morphous and function of normal cells. Clinically, cytokera-tins are used to diagnose several tumors as tumor markers. Recently, numerous studies indicate that the abnor-mal expression, mutation in the site of phosphorylation and hyperphosphorylation have relationship with the mechnism of tumorigenesis. Reseach of the relationship is important for the diagnosis, therapy and prognosis of tumor.

Objective To study the reLationship between blood group antibody IgG titer of pregnant women and ABe hemolytic disease of newborn(HDN).Methods Blood group antibody IgG titem of 2700 pregnant women who is O and Rh positive with a non-O husband were detected.After bom,blood groups,Coomb's test,free antibody and antibody release test were done for those 280 babies who were in high risk of HDN.so that we could understand the relationship between the anlibody IgG level of pregnant women and ABO-HDN.Results The percent of anti-A (B)IgG titer＜64,64,128,256 and≥512 in the 2700 O type pregnant women was 62.4%,16.8%,12.6%,5.8%and 2.4%,respectively.There were 67 babies suffered from HDN in those 280 bahies who had high risk.which accounted for 23.9%.With the anti-A (B)IgG liter was 64,128,256 and≥512,the percent of HND positive was 10.2%,27.8%,45.7% and 50.0%,respectively (P＜0.01).Conclusion There is a positive relationship between blood group antibody IgG liter of pregnant women and ABO-HDN.It is necessary for the pregnant women to detect the level of anti-A(B)IgG.

OBJECTIVE:To explore the material features and biocompartibility of stent implantation in treating intrahepatic biliary stricture under ultrasonic guidance.METHODS:The Chinese Journal Full-text Database and Medline were retrieved by the first author using search terms of "intrahepatic biliary stricture,stent,ultrasonic guidance,and biocompartibility" both in Chinese and English.Meta analysis,unrelated papers-er repetitive studies were excluded.After that,21 documents concerning the material features and biocompartibility of stent implantation in treating intrahepatic biliary stricture under ultrasonic guidance were analyzed.RESULTS:Compared with the Previousl surgery,stent implantation exhibited advantages such as small trauma,better curative effect,able to improve life quality and prolong life.Ultrasonic guidance has shown its clinical values during stent implantation because of accurate location,few traumas,low complication and cheap cost.The metal stents were preferred in treating lower ureteral obstruction,which is superior to plastic stents in preventing bacteria,maintaining stent patency and reducing complications.However,due to easy change and cheap cost,the plastic stents are widely used in treating intrahepatic biliary stricture,especially for patients within 3-month survival times.CONCLUSION:Materials of the stents play a key role in influencing the short-and long-term effectiveness in treating intrahepatic biiiary stricture.Accordingly,the suitable stents should be selected prior to implantation according to the sites,degree,type of obstruction,physical state,expected survival time,economical ability,as well as the prognosis to reach the goals of relieving pain and prolonging life.

In recent years,premature nutritional problems is newborn pediatric paramount concenrn problem.For three material(glucose,protein and fat)metabolism and utilization.premature infants has its own characteristics.In order to avoid side effect,classic parenteral nutrition plan provide for fat emulsion and amino acid gradually,but make premature infants in poor nutrition state.Recent clinical studies have shown that early nutrition is particularly important.Premature infants bom in 24 hours has been given full amount vein nutrition could provide good basis of energy.and avoid associated complications.

Objective To discuss the efficacy and safety of insulin aspart 30 injection combined with Akabo Tang (Acarbose tablets)about treatment of patients with type 2 diabetes.Methods 36 cases of type 2 diabetes were selected,by means of insulin aspart 30 combined acarbose tablets treatment,the levels of fasting plasma glucose (FPG)and glycosylated hemoglobin(HbA1c)before and after treatment were observed.Results The levels of fasting plasma glucose were (10.67 ±2.00)mmol/L and (6.76 ±0.47)mmol/L before and after treatment;The levels of HbA1c were (9.54 ±1.90)% and (7.70 ±0.82)% before and after treatment.After treatment,blood glucose and glycated hemoglobin levels in patients were significantly decreased (t =31.920,P <0.05;t =29.624,P <0.05). Conclusion The treatment that insulin aspart 30 injection combines acarbose tablets for type 2 diabetes patients is a safe,effective and convenient option.

Functional bowel disorders (FBD) refer to a set of bowel symptoms related to the disorders of sensation, secretion and motility yet without a corresponding structural, histological, biochemical, or serological abnormalities.The pathogensesis of FBD is still not very clear.Whether these functional disorders reflect the inadequacy of our understanding of a disease or the limitation of our diagnostic testing is a question.With the development of the biomedical technology, some histological or biochemical changes were revealed, which supported the possibility that organic abnormality might exist in FBD.In this paper the progress of research on organic changes of irritable bowel syndrome and functional constipation was reviewed.

Objective To investigate the feasibility of alanine aminotransferase (ALT)/aspartate aminotransferase (AST) ratio in predicting the degree of hepatic steatosis in chronic hepatitis C (CHC) patients.Methods A total of 231 CHC patients who visited The First People's Hospital of Nanyang from May 2012 to June 2016 were enrolled,among whom 105 (45.45％) had nonalcoholic fatty liver disease (NAFLD) and 126 (54.55％) did not have NAFLD.According to the ultrasound score,the NAFLD group was divided into mild-to-moderate (1-2 points) hepatic steatosis group (n =67) and severe (3 points) hepatic steatosis group (n =38).The two groups were compared in terms of demographic data and disease data including creatinine,fasting blood glucose,ALT,AST,ALT/AST ratio,γ-glutamyltransferase (GGT),uric acid,low-density lipoprotein,high-density lipoprotein (HDL),cholesterol (CHO),and triglyceride (TG) to screen out independent risk factors for NAFLD in CHC patients.The independent samples t-test was used for comparison of normally distributed continuous data between groups,and the Wilcoxon rank sum test was used for comparison of non-normally distributed continuous data between groups;the chi-square test was used for comparison of categorical data between groups;with severe NAFLD as the dependent variable,different factors were introduced into the logistic regression equation to screen out independent risk factors.Results Compared with the non-NAFLD group,the NAFLD group had significantly higher systolic pressure,diastolic pressure,fasting blood glucose,ALT/AST ratio,and levels of ALT,GGT,HDL,CHO,and TG,as well as a significantly higher proportion of patients with diabetes,hypertension,or metabolic syndrome (all P ＜ 0.05).Compared with the severe hepatic steatosis group,the mild-to-moderate hepatic steatosis group had significantly lower systolic pressure,diastolic pressure,fasting blood glucose,ALT/AST ratio,and levels of ALT,GGT,HDL,CHO,and TG,as well as a significantly lower proportion of patients with diabetes,hypertension,or metabolic syndrome (all P ＜ 0.05).The logistic regression analysis showed that metabohc syndrome,ALT,and ALT/AST ratio were independent risk factors for NAFLD (all P ＜0.05),and metabolic syndrome,ALT,ALT/AST ratio,and GGT were independent risk factors for severe NAFLD (all P ＜ 0.05).Conclusion ALT/AST ratio is an independent risk factor for NAFLD in CHC patients and has a certain value in evaluating the degree of NAFLD.

Professor TANG Han-jun is a famous expert of traditional Chinese medicine,he has 50 years’experience in TCM. With the unique theories,rich clinical experience and excellent clinical effect,he has made great contributions to the surgery developmemnt of TCM. The article tries to summarize the essence of TANG Han-jun's clinical experience,as to show the regulation and characteristics and give introduction to the reader. Professor Tang indicates that essence-finding,selection of treamment based on the differential diagnosis and combination differentiation of symptoms and signs with differential diagnosis of disease are pivotial in mastopathy. The main way to administer medicines is enriching qi and nourishing spleen. Two typical cases of Herbal pastes(hyperplasia of mammary glands and mammary carcinoma) are presented.