Objective To explore the effect of acupuncture combined with Guishen Decoction (GD) on serum antisperm antibody (ASAb) level of rat models with immunological infertility. Methods Active immunization was used to establish rat models with positive serum ASAb. Eighty SD rats were alloc ated to four group s: Group A (treated with acupuncture and GD), Group B( treated with GD), Group C (treated with acupuncture), Group D (model control group). GD is composed of Ra dix Re hmanniae Praeparata, Semen Cuscutae, Fructus Ligustri Lucidi, Rhizoma Dioscorae, Fructus Lycii, Ramulus Loranthi, etc.. Results The negative rate of serum A SAb in Group A was significant higher than that in Group B and Group C (P
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