1.Clinical significance of interleukin-17 in nasopharyngeal secretions and serum of wheezing children under 5 years old
Chinese Journal of Postgraduates of Medicine 2011;34(12):27-29
Objective To explore the clinical significance of interleukin (IL)- 17 in nasopharyngeal secretions (NPS) and serum of wheezing children under 5 years old. Methods Fifty-three children with recurrent wheezing under 5 years old were divided into wheezing group Ⅰ (with atopic high risks,27 cases)and wheezing group Ⅱ (without atopic high risks, 26 cases) ;20 children without infectious diseases such as hernia and renal calculus were enrolled as control group. After collecting and dealing their NPS and serum,the levels of IL-17 were measured by double-antibody sandwich enzyme-linked immunosorbent assay (ELISA). Results The levels of IL-17 in serum and NPS in wheezing group Ⅰ [(1469.32 ± 978.30),(1473.70 ±974.35) ng/L],and wheezing group Ⅱ [(263.34 ± 131.80), (788.28±132.40) ng/L] were significantly higher than those in control group [(36.48 ± 2.00), (36.45 ± 5.00) ng/L] (P < 0.01 ), and the levels of IL- 17 in wheezing group Ⅰ were higher than those in wheezing group Ⅱ (P < 0.05 ); the expression of IL- 17 in NPS and serum had a positive correlation (r = 0.313,P < 0.05). Conclusion The detections of IL-17 in NPS can be used as laboratory index to distinguish wheezing children who have a tendency to persistent wheezing, and early intervention and treatment should be given.
2.Clinical observation of Drospirenone and Ethinylestradiol Tablets for preventing postoperative complications of induced abortion
Chinese Journal of Biochemical Pharmaceutics 2016;36(8):74-75
Objective To observe the clinical effect of postoperative complications in patients with induced abortion by taking Drospirenone and Ethinylestradiol Tablets.Methods 400 patients with induced abortion from November 2015 to May 2016 were randomly divided into the observation group and the control group,200 cases in each group.The control group was treated with routine antibiotic therapy.The observation group treatment with Drospirenone and Ethinylestradiol Tablets based on the control group, 1 per one night, 21d for a course of treatment, continuous use of 6 courses.Compared the 2 groups of patients with postoperative complications of pelvic infection,intrauterine adhesions,pregnancy,recurrent abdominal pain and two groups of postoperative recovery time of menstruation,vaginal bleeding,endometrial thickness.Results In the observation group after pelvic infection,uterine cavity adhesion,pregnancy,periodic abdominal pain incidence were 1.5%,0.5%,0.0%,1.5%,were significantly lower than that of the control group7.0%,3.5%,4.0%,5.5%(P<0.05);the observation group after menstruation recovery time,vaginal bleeding,endometrial thickness respectively(27.2 ±1.7) d,(6.2 ±1.4)d,(7.2 ±2.3) mm,were lower than the control group(32.5 ±6.0) d,(7.8 ±2.7) d,(5.0 ±2.4) mm,two groups of the difference was statistically significant(P<0.05).Conclusion After artificial abortion,taking Drospirenone and Ethinylestradiol Tablets can effectively reduce the incidence of complications,improve the quality of life of patients,the method is simple,safe,effective and good compliance.
4.Dynamic modeling and simulating of squatting-standing action of human body.
Jianhui WANG ; Xiulin XU ; Meijun AN ; Xiufang HU
Journal of Biomedical Engineering 2014;31(6):1250-1254
It is very difficult for stroke patients to complete the action of squatting-standing because their equilibrium function ability has been seriously declined. It was necessary, therefore, to do a deep research on the action of human squatting-standing and to set up an accurate model and simulation. In our modeling research, the movements of upper limbs and head was neglected, and a seven-segment model was developed to establish the coordinate system of human squatting-standing action. It calculated the knee joint moment and hip joint moment during squatting and standing by utilizing Lagrange method, and then simulated this mathematical model by utilizing Matlab. Geometric model of human squatting-standing was developed and simulated in ADAMS which proved that the established Lagrange model was reasonable. It would also provide significant theoretical references for further study and development of squatting-standing rehabilitation training equipment.
Biomechanical Phenomena
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Computer Simulation
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Hip Joint
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Humans
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Knee Joint
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Models, Theoretical
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Movement
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Posture
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Upper Extremity
5.Imaging diagnosis methods and progress for lymph node metastasis in esophageal carcinoma
Xiufang WANG ; Xuanzhong ZHENG ; Hongxing JIN
Cancer Research and Clinic 2009;21(5):356-358
The article focuses on diagnostic criteria and diagnostic accuracy of the various imaging methods by lymph node metastasis in esophageal carcinoma at present, and compares accuracy of the various imaging methods. In general, the diagnostic accuracy of CT is lower, the diagnostic accuracy of uhrasmall superparamagnetic iron oxide-enhanced MR imaging is higher. Each imaging method has the lower accuracy for the diagnosis of smaller lymph node metastasis. Diagnostic accuracy of endoscopic ultrasonography is higher in the diagnosis of mediastinal lymph node metastasis. Sensitivity of PET/CT is higher for the diagnosis of distant lymph node metastasis.
6.Effect of Yiqi Huoxue Recipe on Pulmonary Function of Lung Cancer Patients after Radiation Therapy
Xiufang LIU ; Fengyu LI ; Bingsheng WANG
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(08):-
0.05). The pulmonary function in M3 after radiotherapy were lower than that in M1 after radiotherapy of control group (P
7.Effect of Yiqi Huoxue Recipe on the Expression of TGF-?_1 and ?-IFN in Rats with Radiation-induced Lung Injury
Fengyu LI ; Bingsheng WANG ; Xiufang LIU
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(04):-
Objective To observe the effect of Yiqi Huoxue Recipe on the expression of TGF-?1 and ?-IFN in rats with radiation-induced lung injury in different radiation time, and discuss the prevention and curative effect of Yiqi Huoxue Recipe and its possible action mechanism. Methods One hundred and twenty Wistar rats were randomly allocated into irradiation group (n =30), irradiation with Yiqi Huoxue Recipe-treated group (n =30), irradiation with ambroxol-treated group (n =30) and normal control group (n =6). The former three groups were irradiated at right hemithorax with a dose of 30 Gy (5 Gy per week). Animals were followed for 26 weeks after the first irradiation. The levels of serum TGF-?1 and ?-IFN of 6 rats in each group were assayed by ELISA at the end of 4th, 6th, 8th, 12th and 26th week after the first irradiation. Results In Yiqi Huoxue Recipe-treated group, the levels of serum TGF-?1 were significantly lower from the 4th week than that of the irradiation group (P0.05). Conclusion Yiqi Huoxue Recipe can inhibit the excretion of TGF-?1 and promote the excretion of ?-IFN. It suggested that Yiqi Huoxue Recipe might play an important role in the prevention and curation of radiation-induced lung injury.
8.Survey on occlusion of university students
Chaoyun YAN ; Meiqing WANG ; Xiufang YAO
Journal of Practical Stomatology 1995;0(04):-
Objective: To investigate the distribution of abnormal occlusion of permanent dentition in adolescents. Methods: 304 Junior university students aged 16- 18 years old were investigated with their occlusion casts according to the Angle classification and the relationshop of over-jet and over-bite in both anterior and posterior teeth. Asymmetrical Angle category was given to those whose bilateral classifications were different. Results: 19.73% of the subjects were found with normal occlusion. Among the abnormals 58. 05%, 8. 90%, 8. 90% and 24. 15% were found with Angle Ⅰ, Ⅱ, Ⅲ and asymmetrical Angle category respectively. Anterior edge-to-edge relationship, cross-bite, deep over bite, deep-over jet and open bite were 12.71 %, 11.02 %, 5.08%, 5.08 % and 2.12% respectively, posteriorly cross-bite, reverse crosss bite and combination of the two were 19.07%, 17.37% and 0.85 % respectively. Conclusion: The asymmetrical Angle malocclusion and abnormal over-jet and over-bite of both anterior and posterior teeth stand a large ratio in Junior university students.
9.Relation of behavior of buying lottery to risk attitudes and lottery related cognitive distortions in lottery players
Zhen XIAO ; Xiufang DU ; Xiuxin WANG
Chinese Mental Health Journal 2015;(7):543-548
Objective:To explore the relationship among lottery buying behaviors,risk attitudes and lottery re-lated cognitive distortions,in order to propose suggestions about the intervention of problem lottery players and the healthy development of the lottery.Methods:Totally 228 lottery players (120 males,108 females;150 unmarried,78 married)sampled from Jinan were asked to fill out the Questionnaire of Lottery Buying Behavior (LBB),Domain Specific Risk-Taking Scale (DOSPERT)and Lottery Related Cognitive Distortions Scale (LRCD).Correlation a-nalysis and path analysis were used to analyze the data.Results:The scores of irrational behavior of LBB were posi-tively correlated with the DOSPERT total scores and its factor scores of recreation and gambling,and positively cor-related with the LRCD total scores and its factor scores except optimistic (r=0.17 -0.34,Ps<0.01 ).While the scores of rational behavior of LBB were negatively correlated with DOSPERT total scores and factor scores of rec-reation and gambling,and negatively correlated with LRCD total scores and its factor scores of illusion of control, illusory correlation,over optimistic and gamblers'fallacy (r=-0.18 --0.37,Ps<0.01 ).Path analysis showed that lottery related cognitive distortions had complete mediating effect between risk attitudes and irrational behaviorsof buying lotteries.Lottery related cognitive distortions partially mediate the relationship between risk attitudes and rational behaviors of buying lotteries.Conclusion:It suggests that the higher risk attitudes the lottery players hold, the greater cognitive distortions they will have,which in turn the irrational behaviors of buying lotteries might easily to have.
10.An immunohistochemical study of TGF-?1 in monkey mandibular condyle following gradually induced occlusal disorder
Jinwu CHEN ; Meiqing WANG ; Xiufang YAO
Journal of Practical Stomatology 1996;0(02):-
砄bjective:To elucidate the effects of gradually induced occlusal disorder on the expression of TGF ?1 in temporomandibular condyle of monkey. Methods:In a monkey after extraction of right upper first molar and left lower first molar, a fixed orthodontic appliance was used to cause the adjacent teeth inclined to the space and to occlude with opposite in coordinately. Another monkey was used as the control.8 months later, the animals were sacrificed and bilateral temporomandibular condyles were examined with histologic and immunohistochemical methods.Results:In the animal with teeth extraction, degenerative changes were found in anterior medial part of condyles, the thickness of condylar cartilage decreased significantly, especially in the anterior parts of medial and central thirds, and also the intermediate part of medial third ( P