1.Development of Upper Extremity Evaluation Devices (review)
Chinese Journal of Rehabilitation Theory and Practice 2014;(10):916-918
This paper discussed the application of upper extremity rehabilitation devices in rehabilitation evaluation after stroke, focused on some typical kinds of upper extremity rehabilitation systems. It was analyzed that the way to obtain multiple parameter and evaluation indices during the progress of upper extremity rehabilitation evaluation, and viewed the development and application of upper extremity rehabilitation evaluation technology.
2.Dynamic modeling and simulating of squatting-standing action of human body.
Jianhui WANG ; Xiulin XU ; Meijun AN ; Xiufang HU
Journal of Biomedical Engineering 2014;31(6):1250-1254
It is very difficult for stroke patients to complete the action of squatting-standing because their equilibrium function ability has been seriously declined. It was necessary, therefore, to do a deep research on the action of human squatting-standing and to set up an accurate model and simulation. In our modeling research, the movements of upper limbs and head was neglected, and a seven-segment model was developed to establish the coordinate system of human squatting-standing action. It calculated the knee joint moment and hip joint moment during squatting and standing by utilizing Lagrange method, and then simulated this mathematical model by utilizing Matlab. Geometric model of human squatting-standing was developed and simulated in ADAMS which proved that the established Lagrange model was reasonable. It would also provide significant theoretical references for further study and development of squatting-standing rehabilitation training equipment.
Biomechanical Phenomena
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Computer Simulation
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Hip Joint
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Humans
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Knee Joint
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Models, Theoretical
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Movement
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Posture
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Upper Extremity
3.Safety Analysis and Measurement of High-frequency Surgical Equipment
Xiufang HU ; Renling ZOU ; Xiulin XU
Chinese Medical Equipment Journal 2003;0(10):-
High-frequency surgical equipment electrical safety is analyzed based on safety testing standards for GB9706.4,and high-frequency leakage current of GD350-Btype high-frequency surgical equipment is tested by QA-ES.The safety of high-frequency surgical equipment is discussed.
4.Development of Lower Limbs Rehabilitative Training Robot (review)
Jiaojiao ZHANG ; Xiufang HU ; Xiulin XU
Chinese Journal of Rehabilitation Theory and Practice 2012;18(8):728-730
The paper overviewed the research progress of the lower limb rehabilitation training robot at home and abroad, introduced some kinds of representative lower limb rehabilitation training robots, and put forward the prospects of rehabilitation training robot
5.Diagnostic value of vascular endothelial growth factor combined with β-human chorionic gonadotropin for suspected ectopic pregnancy
Hua HU ; Xiaoning YANG ; Xiufang FU ; Jiashi GU
Chinese Journal of Postgraduates of Medicine 2011;34(15):6-9
Objective To explore the diagnostic values of vascular endothelial growth factor (VEGF) and p -human chorionic gonadotropin( β -hCG) for early ectopic pregnancy. Methods The serum levels of VEGF and β-hCG were measured in 109 patients with suspected ectopic pregnancy by ELISA and RIA respectively, receiver operating characteristic (ROC) curvers were established, the diagnostic values of VEGF and β -hCG for ectopic pregnancy were analyzed. Results One hundred and nine patients with suspected ectopic pregnancy were diagnosed in the end: 62 cases with ectopic pregnancy and 47 cases with intrauterine pregnancy. The levels of VEGF in ectopic pregnancy were significantly higher than those in intrauterine pregnancy (P < 0.05), but the levels of β -hCG were significantly lower than those in intrauterine pregnancy (P < 0.05). The areas under ROC curves of VEGF were 0.87, the areas under ROC curves of β -hCG were 0.71. In VEGF > 140 ng/L for diagnosis of ectopic pregnancy, the sensitivity and specificity were 75.8% (47/62) and 80.9% (38/47) respectively. In β-hCG < 1200 U/L for diagnosis of ectopic pregnancy, the sensitivity and specificity were 64.5%(40/62) and 61.7%(29/47) respectively. The sensitivity and specificity of combined detection of VEGF and β -hCG were 80.6%(50/62) and 57.4%( 27/47) respectively. Conclusions The diagnostic values of VEGF are better than those of β -hCG. The combined detection of VEGF and β -hCG can increase the rate of early diagnosis and shorten observation time.
6.Active control of the trajectory of the center of gravity in balance training
Renling ZOU ; Xiufang HU ; Xiulin XU ; Fang LI ; Yi WU
Chinese Journal of Physical Medicine and Rehabilitation 2011;33(2):137-140
Objective To study the impact of active control of the trajectory of the center of gravity on the effectiveness of balance training and balance assessment. Methods Two groups of subjects ( group 1 30-45 years old, group 2 45-60 years old ) were evaluated and trained using both active center of gravity trajectory control and static balance methods. Results The percentages of success in controlling the center of gravity were the same when both groups were trained using static balance. Group 1's success percentage was higher than that of group 2 after active center of gravity trajectory training. Their affected lower limbs performed better in wave trace training than after static balance training, and performance improved with increased wave trace amplitude. Conclusions Wave tracing can stimulate the lower limbs of patients with active control force and improve their balance. The wave assessment is superior to static assessment, as it can objectively reflect ability in active center of gravity control and adjust the lower limbs of subjects whose static balance ability is at the same level.
7.Control System Design and Test of Digital Comprehensive Training Treadmill for Rats.
Xiulin XU ; Guanpo MA ; Jun ZHAO ; Xiufang HU
Journal of Biomedical Engineering 2015;32(6):1233-1238
This article presents the design of a treadmill of comprehensive training experiment for rats. The treadmill is composed of six tracks and two of them were designed as conventional plane, two were designed to swing right and left, and two were designed to swing back and forth. The power was provided by six motors. The MSP430F149 is used as core to adjust the swing rate and the grade of electric shock. The IAR for MSP430 is used to design the software. The speed of the six tracks could be adjusted between 0 and 30 m/min. The swing tracks of back and forth can be swung for 3-25 times per minute and the swing tracks of right and left for 3-32 times. The electric shock can be divided into three levels, i. e. strong, middle, and weak level for each track. The digital comprehensive training treadmill can meet different training needs, and provide experimental data for mechanism research of some related diseases.
Animals
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Equipment Design
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Exercise Test
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instrumentation
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Physical Conditioning, Animal
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instrumentation
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Rats
8.Design of balloon dilatation device for achalasia of cricopharyngeal muscle
Renling ZOU ; Xiufang HU ; Xiulin XU ; Yi WU
Chinese Journal of Tissue Engineering Research 2009;13(52):10309-10312
Obstacles in pharyngoesophageal function are characterized clinically by dysphagia.At present,the treatment for dysphagia is broadly divided into two ways:balloon expansion therapy and electrical stimulation therapy.Balloon dilatation device for achalasia of cricopharyngeal muscle is design based on the principle of expansion treatment to stimulate cricopharyngeal muscle contraction and dilatation through the pressure of balloon dilation.At work,the water was filled in balloon catheter through the electronic charge pump to pressurize to reach a certain pressure of the balloon dilatation,and the drain valve drained water at prescriptive speed until it reaches a certain contraction of the balloon pressure,followed by water filling in the balloon catheter.This operation was repeated operation,resulting in a compression cycle to cricopharyngeal muscle,promote its contraction and dilatation.Patients can gradually restore autonomy of swallowing.The device is easy to operate,safe and reliable.The doctor can fill water in the balloon catheter at certain time and quantity to achieve the treatment of achalasia of cricopharyngeal muscle.
9.Epidemiological analysis of hand-foot-mouth disease in Shanghai Yangpu District during 2005-2008
Xiufang LIANG ; Huimin HUANG ; Meng XIE ; Jiaqi ZHANG ; Jin HU
Chinese Journal of Disease Control & Prevention 2008;0(06):-
Objective To know the epidemiological characteristics of hand-foot-mouth disease in Yangpu District and provide evidence for specific strategies and measures of hand-foot-mouth disease activity prevention and control. Methods Descriptive analysis of the data from hand-foot-mouth disease epidemic situation in Yangpu District from 2005 to 2008 was made. Results 1 348 cases were reported in the whole Yangpu District from 2005 to 2008, and no severe cases, no death. The average morbidity in Yangpu District was 27.48/100 000. The male to female ratio was 1.46∶1. The infection occurred to infants aged from 1 year to 5 years (85.39%). The incidence of the native population children aged 2 to 3 exceeded 10/100 000. The season peak appeared from May to July (70.18%), and outbreaks used to occur at nurseries and kindergartens. The typical clinical presentations mainly included fever and rash. The rash mainly occurred to hands, feet, mouth, buttocks and so on. Conclusions Incidence varied significantly between different sexes, seasons and ages. It can cause large-scale epidemic in a short period of time, the epidemic was very difficult to control, but the leaders attach importance to take the early warning and monitoring, accuratey deal with emergencies, health education promotion and training of comprehensive measures, the epidemic can be effectively controlled.
10.Effects of Paeonol on Aortic NF-κB Activity and Blood Lipid Levels in Rats with Atherosclerosis
Xiufang QIAN ; Changju HU ; Dan LIU ; Lieying QIANG ; Xiaosi SHI
China Pharmacist 2014;(9):1441-1443
Objective:To investigate the effects of paeonol on aortic nuclear factor-kappaB ( NF-κB) activity and blood lipid levels in the rats with atherosclerosis ( AS) . Methods:The AS rat model was established by administration of high-fat diet and vitamin D3 ( i. p. ). The rats were divided into 5 groups (n=8) randomly, namely the normal group, model group, positive control group(simvasta-tin, 10 mg·kg-1 ) and paeonol groups with the dose of 20 and 10 mg·kg-1 , respectively. After the 4-week treatment, the serum of rats was collected to determine the lipid levels. The aortic pathologic changes of AS rats were observed under a microscope, and then graded, and aortic NF-κB activity was detected by an immunohistochemistry method. Results:Administration of paeonol improved the severity of aortic pathology in AS rats. The pathologic grade in the paeonol group (20 mg·kg-1 ) showed a significant difference com-pared with that in the model group (P<0. 05). Paeonol (20 and 10 mg·kg-1) markedly decreased the TG, TC and LDL-C levels in the serum of AS rats (P<0. 05 or P<0. 01). Meanwhile, paeonol significantly inhibited the aortic NF-κB activity(IOD value) with (1. 96 ± 0. 55) and (2. 50 ± 0. 80) in 20 and 10 mg·kg-1 group, respectively, which showed significant differences compared with that in the model group (P<0. 05 or P<0. 01). Conclusion:Paeonol shows certain therapeutic effect in AS rats, and the mechanisms may be related with the regulation of lipid mobilization and the inhibition of aortic NF-κB activity.