Clinical data of 40 cases of advanced schistosomiasis complicated with liver cancer were analyzed in this paper.

Objective To evaluate the effects of 3 molluscicides namely 5%niclosamide ethanolamine granules,4%“Luo-wei”(Tea-seed distilled saponins,TDS)and 50%wettable powder of niclosamide ethanolamine salt(WPN)by spraying and pou-drage methods in marshland and lake regions in dry season. Methods An environment with a high snail density was chosen as the experimental field,then the spraying and poudrage experiments were carried out in the field to assess the molluscicidal effects of 5%niclosamide ethanolamine granules,TDS and WPN delivered by spraying and poudrage methods with a concentration of 30, 6 and 2 g/m2,respectively,and the molluscicidal effects of the 3 drugs by the two methods were evaluated and compared in differ-ent time. Results After the delivery for 15 d,the adjusted snail death rates of the 5%niclosamide ethanolamine granules,TDS and WPN in the spraying experiment were 79.00%,82.29%and 84.83%,respectively,and those in the poudrage experiments were 97.42%,95.27% and 96.62%,respectively. Conclusion The molluscicidal effect of poudrage method is better than the spraying method,and the former is worthy of further extension and application in the marshland in dry season.

Objective To evaluate the reliability and validity of SF-36 in patients with advanced schistosomiasis,so as to proride scientific basis for the selection of suitable tools for health measure.Methods A Chinese version of SF-36 scale was applied to evaluate the health of patients with advanced schistosomiasis by a household survey in Hanshou County of Hunan Province and Jiangling County of Hubei Province,then the reliability and validity of the scale were tested.Results Atotal of 326 patients were investigated in the two counties.The split-half reliability(with a split-half coefficient of 0.95) and the internal consistency (Cronbach'α coefficients of the eight dimensions ranged from 0.86 to 0.88)were satisfying;the convergent and discriminative validity were high with the test successful rates of 97.14%and 87.86%,respectively;the criterion validity was acceptable with a correlation coefficient between the total score of SF-36 and EQ-5D+C VAS score of 0.70.However,the construct validity seemed to be not so reasonable as only 2 dimensions out of 8 were completely in accordance with the theoretical model on factor loading.The percentages of floor effect and ceiling effect in most dimensions were not significant except RP and RE(with the percentages of floor effect of 50.31%and 48.16%,respectively).Conclusions SF-36 is appropriate to be used in patients with advanced schistosomiasis.but some items need to be improved according to the local settings of endemic areas.