Objective To evaluate effect of comprehensive health intervention on serum lipids in obese children.Methods Totally 67 obese children (obesity group) who were treated in Baoan People's Hospital re-ceived one-year comprehensive health interventions. Another 65 normal-body-weighted children were recruited as control group.The changes of body height,weight,BMI,blood pressure (BP),and serum lipids were recorded before and after interventions.Results Compared with the control group,the weight,BMI,BP,TG,and LDL-C in the obesity group significantly decreased (P<0.05 or P<0.01).The BMI,BP,and TG in the obesity group were significantly improved after intervention (P<0.05 or P<0.01).HDL-C was significantly higher than the pre-intervention level (P<0.05),while was significantly lower than that in the control group (P