Objective:To evaluate the value of DSA in diagnosis of intestinal vascular malformation.Methods:The clinical and DSA characters in 8 patients with small intestinal malformation were analyzed.There were 6 males and 2 females.All patients were underwent selective and supper selective superior mesenteric inferior mesenteric or colic artery angiographies.Results:The clinical fectures:1)the main sympton is acute lower gastrointestinal bleeding;(2)the results of conventional examination were generally negative;(3)the hemoglobin was dropped down to 4～6 g/ml in a short period.DSA feactures included:(1)artery-vein fistula;(2)markedly stainning in local small intestinal walls;(3)abnormal hyperplasia and distubance of small vessels.Conclusion:DSA is the most valuable method in diognosis of atute intestinal bleeding.

Objective To investigate the effects and mechanisms of extraction centipede extraction (CE) on grafting hepatocellular carcinoma (HCC) in nude mice.Methods We set up model of Bel-7404 cells heterotopic grafting HCC in nude mice,and observed the tumor growth and metastasis after intragastric administration of CE (treatment group).Immunohistochemical methods were used to detect X-chromosome linked inhibitor of apoptosis protein(XIAP),bax gene,vascular endothelial growth factor(VEGF) and angiopoietin-2(Ang-2) in tumor tissue.Results There was distinctive inhibitive effect of CE on in Bel-7404 cells heterotopic grafting HCC in nude mice.The staining cells population,staining intensity and the optical density(OD)of XIAP,VEGF and Ang-2 in the control group were higher than those in treatment group,but those of BAX were lower than that in treatment group,and there was significant difference between the 2 groups(P

砄bjective:To investigate the consistency of Streptococcus mutans and Streptococcus sobrinus isolates identified by colony morphology,biochemical tests and DNA base content analysis.Methods:46 clinical isolates (30 of S.mutans and 16 of S.sobrinus ) were identified by colony morphology,biochemical tests and determination of DNA base contents with reversed phase high performance liquid chromatography. S.mutans Ingbritt and S.sobrinus 6715 were used as the controls. Results:The DNA contents (G+C mol%) of S.mutans and S.sobrinus clinical isolates, identified by colony morphdogy and biochemical test, were 37.52 and 45.19 respectively,consistent with the expected 36～38 and 44～46 mol percent of G+C.Conclusion: S.mutans and S.sobrinus isolates,identified by colony morphology and biochemical tests ,were consistent with the DNA G+C content analysis. S.mutans and S.sobrinus can be easily and reliably identified by colony morphology and biochemical tests.

0.05). S.sobrinus strains had significantly lower initial adhesive ability to saliva coated hydroxyapatite in the absence of sucrose than S.mutans (P

Objective To determine the prevalence and clinical characteristics of orthostatic hypotension (OH) and orthostatic hypertension (OHT) in the elderly patients with hypertension.Methods 489 elderly patients with hypertension were enrolled and divided into the OH group,the OHT group and the non-OH-OHT group,which represents no or symptom.The orthostatic blood pressure was measured in supine position after resting for more than 5 minutes and at 3 min standing.Results The prevalence of OH in the 60～79 years old group was lower than that in ≥ 80 years old group.The morbility of coronary heart disease,diabetes and ischemic stroke was significantly higher in the OH and OHT group than that in the non-OH-OHT group.Conclusions OH and OHT are common disease in the elderly patients with hypertension and associated with increased risk of cardiovascular disease and diabetes mellitus.To strengthen nursing and health education for elderly patients with hypertension could prevent the incidence of malignant cardiovascular events due to OH and OHT.

ObjectiveTo study the fluoride level of preschool children influenced by fluoride toothpaste. MethodsAbout 200 children aged 3～6 years old were involved in the test. The children of test group were given fluoride toothpaste while the children of control group were given non-fluoride toothpaste. After two months, hair samples were gasified by high temperature and were tested with fluoride-specific electrode. Urinary fluoride concentration and 24h urinary fluoride excretion were also conducted by using fluoride-specific electrode.ResultsIt shows that the 24h urinary fluoride excretion and the fluoride concentration in hair and urine of children in control group were apparently lower than those of children in test group.ConclusionFluoride toothpastes used by preschool children may result in the change of fluoride level in their bodies under the stability of their daily habits and living cir cumstances. Age is likely to be one of the facts that can influence the fluoride ingestion level.

Baicalein is an important component of traditional Chinese herb, Scutellariae Radix(Huang Qin), and has various efficacies, including anti bacterial, antivirus, anti inflammation, protecting the liver function, diuresis, anti tumor, and shows good values in clinical application. It was majorly applied to acute or chronic inflammation. This article reviews developments in its pharmacological action and mechanism and provides theoretical evidences for exploiting of baicalein.

Objective To evaluate the completion of a goal in elimination of iodine deficiency disorders IDD) in the 12th five-year plan for prevention and control of endemic diseases,to analyze the present situation of IDD in prevention and to improve sustainable control strategies in the city of Wuhai in Inner Mongolia.Methods In 2015,using the specific sampling method,5 units were selected from 3 counties of Wuhai according to their subarea positions of east,south,west,north and center,and then 1 township was randomly selected from each unit,40 school children (half males and half females) aged 8-10 and 20 pregnant women were investigated in each township.Goiter of children aged 8-10 was examined by B ultrasonic,the urinary iodine levels were detected by acid digestion arsenic-cerium contact method and the salt iodine levels were measured with the method of direct titrimetric method.Results Totally 900 edible salt samples of local residents had been examined and the median iodized salt iodine was 24.2 mg/kg,the consumption rate of iodized salt was 99.56％ (896/900),the coverage rate of iodized salt was 99.78％ (896/900),and the rate of qualified iodized salt was 99.78％ (898/898).The goiter rate of children was 0.33％ (2/600),urinary iodine level (UI) median was 221.6 μg/L in 600 children aged 8-10,the ratio of urinary iodine levels between 100-199 μg/L was 31.7％ and the median of urinary iodine was 122.15 μg/L in 300 pregnant women,the ratio of urinary iodine between 150-250 μg/L was 26.7％ (80/300).Conclusion Wuhai has achieved the goal of prevention and control of endemic disease prevention andcontrol of the 12th five-year plan,and reached the continuous state of elimination of IDD.

OBJECTIVE:To provide reference for rational clinical use of drugs and sound management thereof. METH-ODS:The relative data of antihypertensive drugs applied in 34 hospitals in Wuhan city during 2011 and 2013 were analyzed sta-tistically by using the analytical method of the Defined Daily Dose(DDD)recommended by WHO. RESULTS:Both consump-tion amount and DDDs of antihypertensive drugs in Wuhan city were increasing during 2011 and 2013,where calcium-channel blockers(CCB)enjoyed the largest consumption amount and the highest DDDs,with the constituent ratio of over 40% respec-tively,followed by angiotensinⅡreceptor antagonist (ARB) and angiotensin converting enzyme inhibitors (ACEIs). The con-sumption amount and DDDs of new compound preparation also increased. Top three single drugs in terms of consumption amount were amlodipine,levamlodipine and valsartan,while amlodipine,nifedipine and felodipine ranked the top three in DDDs list. CONCLUSIONS:Wide usage of antihypertensive drugs in Wuhan City are respectively CCB,ARB,ACEI,adrener-gic receptor blockers and diuretics,which are applied in current principle of antihypertensive drugs use and basically rational in clinical application.

Objective To study the apoptosis in human gastric cancer cell BGC-823 induced by the components in serum of Banxia Xiexin prescription and different herbal fomulation. Method multiplication of cell BGC-823 was observed with MTT method. The genic expression of bcl-2 was tested by S-P immunohistochemistry tehnique. Results As for inhibition of cell BGC-823 multiplication, the groups of Xinkai, Kujiang and Xinku in Banxia Xiexin prescription and different herbal fomulation was dose-dependent and more sensitive than the groups of Xingan, Kugan, Ganbu and the intact prescription (P